Category: 197958-29-5

Bagherzadeh, Nastaran published the artcileSustainable and recyclable magnetic nanocatalyst of 1,10-phenanthroline Pd(0) complex in green synthesis of biaryls and tetrazoles using arylboronic acids as versatile substrates, Application of 2-Pyridinylboronic acid, the publication is Molecular Catalysis (2021), 111489, database is CAplus.

A magnetic nanocatalyst was purveyed as a heterogeneous recoverable palladium-based catalyst anchored on green, sustainable and phosphine free support. Resulted Fe3O4@SiO2-Phen-Pd(0) nanocatalyst bearing powerful phenanthroline ligand was thoroughly characterized by physicochem. approaches like UV-vis, FT-IR, EDX, XRD, TGA, ICP, VSM, DLS, FESEM, and TEM analyses. After finding trustable data, the obtained magnetic catalyst was considered to be applied in the Suzuki-Miyaura type C-C couplings and getting corresponding tetrazoles using arylboronic acid derivatives as alternate precursors of aromatic halides and stupendous data were observed

Molecular Catalysis published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Application of 2-Pyridinylboronic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Gavhane, Dinesh S. published the artcileNano Copper Catalyzed Microwave Assisted Coupling of Benzene Boronic Acids with Thiophenols, Category: pyridine-derivatives, the publication is Letters in Organic Chemistry (2019), 16(6), 491-494, database is CAplus.

A proficient, microwave mediated methodol. using CuFe₂O₄ nanoparticle as the catalyst for S-arylation of substituted benzene boronic acids with thiophenol was developed. In this method, the substituted thioethers were easily obtained through a C-S bond formation using microwave irradiation technique as well as conventional heating in the presence of CuFe₂O₄ nanoparticles with modest to excellent yields with the less reaction time. The ligand free microwave technique helped in the preparation of substituted thioethers in measurable amount within 10 mins. The same results were obtained with conventional heating in 12h. The reported method was economically efficient and an alternative to the initial existing method for the preparation of substituted thioethers.

Letters in Organic Chemistry published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Zeng, Qingbei published the artcileSynthesis and SAR studies of benzimidazolone derivatives as histamine H₃-receptor antagonists, Related Products of pyridine-derivatives, the publication is Bioorganic & Medicinal Chemistry Letters (2013), 23(21), 6001-6003, database is CAplus and MEDLINE.

A novel series of benzimidazolone-containing histamine H₃-receptor antagonists were prepared and their structure-activity relationship was explored. These benzimidazolone analogs demonstrate potent H₃-receptor binding affinities, no P 450 enzyme inhibition, and strong H₃ functional activity. Compound I exhibits the best overall profile with H₃K_i = 0.95 nM and rat AUC = 12.9 μM h.

Bioorganic & Medicinal Chemistry Letters published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C19H21N3O3S, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Aharon, Cheryl published the artcileUsing fluoroform for constructing aromatic and heterocyclic trifluoromethylselenyl compounds, Recommanded Product: 2-Pyridinylboronic acid, the publication is Journal of Fluorine Chemistry (2021), 109866, database is CAplus.

Fluoroform is used to prepare CuCF₃ according to literature procedures. This nucleophilic trifluoromethyl moiety was reacted with aromatic and heterocyclic selenium cyanide derivatives 3-R-4-N(R₁)(R₂)-5-R³C₆H₂SeCN (R = H, Me, Br; R¹ = H, Et, Ac; R² = H, Et, Ac; R³ = H, Me), 3-R⁴-4-R⁵-C₆H₃SeCN (R⁴ = H, Me; R⁵ = Me, t-Bu, Cl, etc.), I (R⁶ = H, Br; R⁷ = H, SeCN; R⁸ = H, SeCN) and II (X = O, S) resp. to form the corresponding trifluoromethylselenium compounds 3-R-4-N(R₁)(R₂)-5-R³C₆H₂SeCF₃, 3-R⁴-4-R⁵-C₆H₃SeCF₃, III (R⁹ = H, SeCF₃; R¹⁰ = H, SeCF₃) and IV. Selenium cyanides were made with 1,3-dicyanotriselenide prepared in situ from malononitrile and selenium dioxide. The electrophilicity of the reagent (^δ+SeCN) was enough to attack aniline derivatives 3-R-4-N(R₁)(R₂)-5-R³C₆H₃ at the para position, but with other aromatics it was advantageous to use the corresponding boronic acids 3-R⁴-4-R⁵-C₆H₃B(OH)₂, V (R¹¹ = H, B(OH)₂; R¹² = H, B(OH)₂) and VI as the moiety was easily displaced by the selenium cyanate moiety.

Journal of Fluorine Chemistry published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Recommanded Product: 2-Pyridinylboronic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lavit, Kseniya published the artcileZooming in on the hydrated imidazoline ring expansion: Factors influencing the rate of N â†?N’ aroyl migration in N-aroyl-N-(hetero)aryl ethylenediamines, Related Products of pyridine-derivatives, the publication is Tetrahedron Letters (2020), 61(42), 152423, database is CAplus.

The influence of electronic factors on the rates of N â†?N’ aroyl migration in N-aroyl-N-(hetero)aryl ethylenediamines was examined Electron-withdrawing substituents on the aroyl group weakly accelerate the reaction (in linear correlation with the Hammett σ_p constants). Much stronger influence came from the nitrogen-bound aromatic group which gave a strong linear correlation with the Hammett σ^–_p constants For electron-deficient heteroaromatics and nitroaroms., the migration was nearly instantaneous in basic medium. These findings will significantly impact the planning of mechanistically related transformations of N-(2-aminoethyl) lactams through the hydrated imidazoline ring expansion (HIRE) process.

Tetrahedron Letters published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Fernandez, Estefania published the artcileBase-Controlled Heck, Suzuki, and Sonogashira Reactions Catalyzed by Ligand-Free Platinum or Palladium Single Atom and Sub-Nanometer Clusters, Category: pyridine-derivatives, the publication is Journal of the American Chemical Society (2019), 141(5), 1928-1940, database is CAplus and MEDLINE.

The assumption that oxidative addition is the key step during the cross-coupling reaction of aryl halides has led to the development of a plethora of increasingly complex metal catalysts, thereby obviating in many cases the exact influence of the base, which is a simple, inexpensive, and necessary reagent for this paramount transformation. Here, a combined exptl. and computational study shows that the oxidative addition is not the single kinetically relevant step in different cross-coupling reactions catalyzed by sub-nanometer Pt or Pd species, since the reactivity control is shifted toward subtle changes in the base. The exposed metal atoms in the cluster cooperate to enable an extremely easy oxidative addition of the aryl halide, even chlorides, and allow the base to bifurcate the coupling. With sub-nanometer Pd species, amines drive to the Heck reaction, carbonate drives to the Sonogashira reaction, and phosphate drives to the Suzuki reaction, while for Pt clusters and single atoms, good conversion is only achieved using acetate as a base. This base-controlled orthogonal reactivity with ligand-free catalysts opens new avenues in the design of cross-coupling reactions in organic synthesis.

Journal of the American Chemical Society published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Zurwerra, Didier published the artcileSynthesis and Stability of Boratriazaroles, Safety of 2-Pyridinylboronic acid, the publication is Organic Letters (2015), 17(1), 74-77, database is CAplus and MEDLINE.

We describe the synthesis and stability anal. of novel boratriazaroles that can be viewed as bioisosteres of imidazoles or pyrazoles. These heterocycles could conveniently be obtained by condensing a boronic acid and amidrazone 1 in various solvents. A detailed stability anal. of selected compounds at different pH values as a function of time led to the identification of steric hindrance around the boron atom as a key element for stabilization.

Organic Letters published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C10H9ClN2O, Safety of 2-Pyridinylboronic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Bhaskar, Boyapally published the artcileTamarindus indica seed ash extract for C-C coupling under added organics and volatile organic solvent-free conditions: a waste repurposing technique for Suzuki-Miyaura reaction, COA of Formula: C5H6BNO2, the publication is Environmental Science and Pollution Research, database is CAplus and MEDLINE.

A tremendous research has been appeared on Pd-catalyzed Suzuki-Miyaura cross-coupling (SMC) during the last four decades due to its high prominence in constructing biaryl motifs of several complexes as well as simple organic compounds of high biol. and com. significance. The use of organic solid waste-derived materials for SMC in benign solvents like water/aqueous media is a very good achievement in these cases. We report in this article the usability of water extract of Tamarindus indica seeds ash (WETS) as a renewable base and reaction medium for Pd(OAc)₂-catalyzed SMC reaction at room temperature (RT). The WETS has been characterized using powder XRD, EDAX, SEM, and FTIR anal. Furthermore, this process is highly environmentally beneficial by the waste repurposing to prominent chem. transformation along with the advantages such as ambient condition and avoids non-renewable chems. like volatile organic solvents, ligands, promoters, and bases. Based on these merits and the quick reactions with high yields of products, this method can attain the interest of the scientific community in exploring the waste-derived ashes to significant chem. transformations.

Environmental Science and Pollution Research published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, COA of Formula: C5H6BNO2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lakshmidevi, Jangam published the artcileA quick and low E-factor waste valorization procedure for CuCl-catalyzed oxidative self-coupling of (hetero)arylboronic acid in pomegranate peel ash extract, Category: pyridine-derivatives, the publication is Green Chemistry Letters and Reviews (2022), 15(3), 538-545, database is CAplus.

The application of waste biomass-derived materials to synthetic chem. is a remarkable achievement, and the use of aqueous media is further advancement. The switch towards earth’s abundant metals like cobalt/copper/iron/nickel from precious palladium in C-C coupling reactions is also a high throughput in the global sustainability perspective. Herein, we describe a CuCl-catalyzed homocoupling of (hetero)arylboronic acids (HABAs) in water extract of pomegranate ash (WEPA) with low E-factor of 1.25 without including the column chromatog. separation of products, which helped in understanding the effectiveness of this method on comparison to reported protocols lacking amounts of silica gel and eluents, however, it was 171.64 by including column purification The reactions are conducted at room temperature to deliver self-coupling products with 90-99% yields in 10-45 min under precious metal, ligand, non-renewable base, toxic/problematic organic solvent and added oxidant-free conditions. A wide range of substrates were screened with aryl and heteroaryl moieties containing diversified functional groups. The substitution of earth’s rare metals-based catalysts by abundant copper, exploration of waste to state-of-the-art C-C coupling, use of biorenewable base, aqueous media, ambient conditions, operational simplicity, excellent yields of biaryls and quick reactions are the noteworthy advantages of this protocol.

Green Chemistry Letters and Reviews published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Rao, H. Surya Prakash published the artcileCopper-catalyzed C(sp³)-C(sp²) cross-coupling. Synthesis of 4-aryl-2-alkyl-amino-3-nitro-4H-chromenes, COA of Formula: C5H6BNO2, the publication is European Journal of Organic Chemistry (2014), 2014(17), 3646-3655, database is CAplus.

Inexpensive copper(II) acetate effectively catalyzes cross-coupling of electron-deficient as well as electron-rich arylboronic acids with 4-methylsulfanyl-2-alkylamino-3-nitro-4H-chromenes under near neutral conditions at room temperature to furnish a range of 4-aryl-4H-chromenes. This new strategy enabled substitution of the C(4)SMe group present on a sp³ hybridized carbon of the 4H-chromenes with aryl/heteroaryl groups. Mechanistic probing revealed that the Cu(I)-Cu(III) cycle is involved in catalysis. One-pot sequential substitution of C(4)SMe followed by C(6)Br with aryl groups was achieved through Cu(OAc)₂ and Pd₂(dba)₃ (Suzuki coupling) catalysis. © 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

European Journal of Organic Chemistry published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, COA of Formula: C5H6BNO2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem