Category: 2215-33-0

Montes, R. published the artcileKinetic determination of nitrite in drinking water by fluorometry, Application of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Analytical Sciences (1991), 7(3), 467-71, database is CAplus.

A method for the kinetic determination of nanogram amounts of NO₂^– is based on its acceleration of the rate of bromination of pyridine-2-aldehyde 2-pyridylhydrazone in acidic medium. The reaction is followed by fluorometry while monitoring the formation of a fluorescent product using an excitation wavelength of 291 nm and an emission wavelength of 432 nm. The method was applied to drinking water anal., with a detection limit of 4.6 ng/mL and recoveries 92-105%. The relative standard deviation of the method is 2.4%. The major advantages of this method are simplicity, absence of a reagent blank, selectivity, and sensitivity.

Analytical Sciences published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Application of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Montes, Rafael published the artcileCoupling of redox and complex formation processes for the kinetic determination of palladium, Safety of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Analyst (Cambridge, United Kingdom) (1985), 110(11), 1339-41, database is CAplus.

A kinetic-spectrophotometric procedure for the determination of μg amounts of Pd(II) with pyridine-2-aldehyde 2-pyridylhydrazone (I) is described. The bromate oxidation of the dye is followed at 372 nm. The method is based on the decrease in the reaction rate produced by Pd complexation of I. A relative standard deviation of 2.5% was obtained in the range 0.5-3.2 μg/mL of Pd. Factors influencing the sensitivity and interferences from model solutions are discussed.

Analyst (Cambridge, United Kingdom) published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Safety of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Perlovich, German L. published the artcileSolubility and Transfer Processes of Some Hydrazones in Biologically Relevant Solvents, Category: pyridine-derivatives, the publication is Journal of Chemical & Engineering Data (2013), 58(9), 2659-2667, database is CAplus.

Solubility values of 20 hydrazones in water, 1-octanol and hexane were determined by the isothermal saturation method. Thermophys. characteristics of fusion processes (m.ps. and fusion enthalpies) of the selected substances were measured by DSC method. The impact of structural modification of the mols. on solubility processes in the solvents was analyzed. Transfer processes from water to 1-octanol and from water to hexane were analyzed. Correlation equations connecting the transfer coefficients with physicochem. descriptors were obtained.

Journal of Chemical & Engineering Data published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Category: pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Vantomme, Ghislaine published the artcileAdaptation in Constitutional Dynamic Libraries and Networks, Switching between Orthogonal Metalloselection and Photoselection Processes, Formula: C11H10N4, the publication is Journal of the American Chemical Society (2014), 136(26), 9509-9518, database is CAplus and MEDLINE.

Constitutional dynamic libraries of hydrazones ^aA^bB and acylhydrazones ^aA^cC undergo reorganization and adaptation in response to a chem. effector (metal cations) or a phys. stimulus (light). The set of hydrazones [¹A¹B, ¹A²B, ²A¹B, ²A²B] undergoes metalloselection on addition of zinc cations which drive the amplification of Zn(¹A²B)₂ by selection of the fittest component ¹A²B. The set of acylhydrazones [E-¹A¹C, ¹A²C, ²A¹C, ²A²C] undergoes photoselection by irradiation of the system, which causes photoisomerization of E-¹A¹C into Z-¹A¹C with amplification of the latter. The set of acyl hydrazones [E-¹A¹C, ¹A³C, ²A¹C, ²A³C] undergoes a dual adaptation via component exchange and selection in response to two orthogonal external agents: a chem. effector, metal cations, and a phys. stimulus, light irradiation Metalloselection takes place on addition of zinc cations which drive the amplification of Zn(¹A³C)₂ by selection of the fittest constituent ¹A³C. Photoselection is obtained on irradiation of the acylhydrazones that leads to photoisomerization from E-¹A¹C to Z-¹A¹C configuration with amplification of the latter. These changes may be represented by square constitutional dynamic networks that display up-regulation of the pairs of agonists (¹A²B, ²A¹B), (Z-¹A¹C, ²A²C), (¹A³C, ²A¹C), (Z-¹A¹C, ²A³C) and the simultaneous down-regulation of the pairs of antagonists (¹A¹B, ²A²B), (¹A²C, ²A¹C), (E-¹A¹C,²A³C), (¹A³C, ²A¹C). The orthogonal dual adaptation undergone by the set of acylhydrazones amounts to a network switching process.

Journal of the American Chemical Society published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C15H21BO3, Formula: C11H10N4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Asuero, Agustin G. published the artcileSpectrophotometric evaluation of acidity constants of two-step overlapping equilibria from the inflexion points of the absorbance versus pH graphs with application to the dipyridylglyoxal mono-(2-pyridyl)hydrazone system, Product Details of C11H10N4, the publication is Acta Pharmaceutica Technologica (1988), 34(3), 164-8, database is CAplus.

Some pyridylhydrazone type derivatives are being currently studied from a pharmacol. point of view. In this respect, the knowledge of acidity constants of a drug is of great worth in solving fundamental problems of pharmaceutical interest. Thus, an extension of the method of Irving, Rossotti and Harris (1955) for the evaluation of acidity constants of diprotic acids is presented. A simple method of developing the final equations given by those authors in a more usual anal. form is also presented, thus providing a rapid and convenient desk method of calculation The methods devised were applied to the evaluation of acidity constants of dipyridylglyoxal mono-(2-pyridyl)-hydrazone (DMPH). Results obtained agree well with those obtained by applying a three equation procedure.

Acta Pharmaceutica Technologica published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Product Details of C11H10N4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Shah, Sonya C. published the artcileCovalent modification of cytochrome c with a hydrazone complex of platinum(II), COA of Formula: C11H10N4, the publication is Journal of the Serbian Chemical Society (1988), 53(3), 139-48, database is CAplus.

The complex Pt(sbpaphy)Cl^– (where sbpaphy is 2-(3-sulfobenzoyl)-pyridine-2-aldehyde 2′-pyridylhydrazone) modifies selectively the histidine (His) 33 residue in horse heart cytochrome c at pH 7.0. The reaction takes place under mild conditions and the Pt(sbpaphy)His label is stable at pH 7.0. The binding site is identified by UV-vis spectrophotometry and by studies of model complexes. The labeled protein is purified readily by cation-exchange chromatog. and the inorganic chromophore in it is quantitated easily owing to its strong UV absorption bands. Cyclic voltammetry, differential-pulse voltammetry, and UV-vis spectrophotometry show that labeling does not perturb the protein.

Journal of the Serbian Chemical Society published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C6H17NO3Si, COA of Formula: C11H10N4.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Butler, Richard N. published the artcileStereoisomerization in heterocyclic hydrazones derived from 2-acylpyridines and their oxidative cyclization with mercury(II) acetate and lead tetraacetate to fused 1,2,4-triazoles and 1,2,3-triazolium systems, Recommanded Product: 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1984), 2109-16, database is CAplus.

Fourteen hydrazones I (R = H, Me, Ph; R¹ = 2-pyridyl, 4-O₂NC₆H₄, Ph, 4-BrC₆H₄, 4-MeOC₆H₄, 4-MeC₆H₄), prepared by coupling 2-formyl-, -benzoyl-, or -acetylpyridine with H₂NNHR¹ (R¹ as before), were isolated predominantly as E isomers, when the acyl substituent R was small (H = Me). When R = Ph, significant yield of Z isomers containing an intramol. H bond were also obtained. The structure of E-I (R = R¹ = Ph) was determined by x-ray crystallog. Oxidation reactions of I were not configuration dependent contrary to the report of R. Kuhn and W. Munzig (1952). A common metallo intermediate II, was obtained by oxidation of E– and Z–I (R = H, R¹ = 2-pyridyl) with Hg(OAc)₂. In Pb(OAc)₄ oxidation of the hydrazones, the product controlling factor was the nature of the methine substituent R. For the ketone derivatives I (R â‰?H), oxidation to fused 1,2,3-triazolium systems occurred via a 5-exo–tet cyclization with E- and Z-hydrazones, whereas for aldehyde systems, I (R = H), the oxidation involved dehydration to a nitrilimine and gave products by solvent addition or a 5-endo–dig cyclization to fused 1,2,4-triazolo systems. Thus, Pb(OAc)₄ oxidation of E– or Z–I (R = Ph, R¹ = 4-O₂NC₆H₄) gave 80% triazolopyridinium III, whereas similar oxidation of E– or Z–I (R = H, R¹ = 2-pyridyl) gave 73-86% triazolopyridine IV.

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Recommanded Product: 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Butler, Richard N. published the artcileDetection of a metalo intermediate and geometrical isomerizations in an oxidative cyclization of a heterocyclic hydrazone with mercury(II) acetate, Name: 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Journal of the Chemical Society, Chemical Communications (1981), 376-7, database is CAplus.

Oxidative cyclization of the (E)-hydrazone I on treatment with Hg(OAc)₂ (AcOH, 70°, 16 h) gave 37% II, via the (Z)-intermediate III. The reaction mechanism, which involves a series of cis-trans isomerizations, is discussed.

Journal of the Chemical Society, Chemical Communications published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Name: 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lee, Kum-Tatt published the artcileDetermination of serum iron and zinc by atomic absorption spectroscopy, Safety of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Mikrochimica Acta (1974), 65-72, database is CAplus and MEDLINE.

An improved, rapid, and precise method was developed for the simultaneous determination of Fe and Zn in serum by at. absorption spectroscopy. The new procedure avoided the clogging of the burner head and possible contamination from Hb Fe, which could occur in other at. absorption methods; it also yielded accurate data when the Fe concentration was <200 μg/100 ml serum, as well as in the higher ranges. The method dependend upon the efficient complexing of serum Fe and Zn with pyridine-2-aldehyde 2-pyridylhydrazone. Although these metal chelates were practically insoluble in aqueous media, by shifting the pH to the alk. side with KOH, they could be extracted quant. into an organic solvent, such as amyl alc. This organic extract could then be aspirated into the air-C2H2 flame of the spectrometer. Even in the lower ranges, the procedure yielded good reproducibility. The method can also be applied to urine samples.

Mikrochimica Acta published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Safety of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Burns, D. Thorburn published the artcileSpectrophotometric or spectrofluorimetric determination of cobalt in steels by extraction as bis[1-(2-pyridylmethylene)-2-(2-pyridyl)hydrazine]cobalt(III) dimethoxyanthracenesulfonate, Synthetic Route of 2215-33-0, the publication is Analytica Chimica Acta (1983), 151(1), 245-9, database is CAplus.

The steel sample was dissolved and Co was reacted with 1-(2-pyridylmethylene)-2-(2-pyridyl)hydrazine (PAPY) and dimethoxyanthracenesulfonate (DMAS) at pH 3 to form an ion-pair complex. The latter was extracted into 1:9 Me₂CO-1,2-dichloroethane. The absorbance and fluorescence of the organic phase was measured at 496 nm and 450 nm (λ_exc = 396 nm), resp. Beer’s law was obeyed for 0-5 μg Co/10 mL. The relative standard deviation was 1.3 and 1.5% for the spectrophotometric and fluorometric, resp., determination of 4 μg Co. The molar absorptivity of the Co(PAPY)₂DMAS ion-pair complex was 3.23 × 10⁴. The detection limit was 0.003 and 0.004 μg Co/mL for the spectrophotometric and fluorometric determination, resp. The effect of diverse ions was studied.

Analytica Chimica Acta published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Synthetic Route of 2215-33-0.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem