Reference of 22620-34-4, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 22620-34-4, name is (5-Chloro-3-pyridinyl)methanol. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of (5-chloropyridin-3-yl)methanol (292 mg, 2.03 mmol) in dry DCM (10 ml) Mn02 (3.54 g, 40.6 mmol) was added. The mixture was stirred at rt o.n. The solid was filtered (washing with DCM) and the solution was evaporated to dryness to give the title compound (128 mg, 0.9 mmol, purity: 85 % by NIVIR, recovery: 44 %). MS (m/z) 142, 144(M+H).
According to the analysis of related databases, 22620-34-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; ANDERSON, Niall Andrew; BANDYOPADHYAY, Deepak; DAUGAN, Alain Claude-Marie; DONCHE, Frederic G.; EIDAM, Patrick M.; FAUCHER, Nicolas Eric; GEORGE, Nicolas S.; HARRIS, Philip Anthony; JEONG, Jae U.; KING, Bryan W.; SEHON, Clark A.; WHITE, Gemma Victoria; WISNOSKI, David Duff; (177 pag.)WO2016/185423; (2016); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem