Category: 39856-58-1

Iqbal, Naeem published the artcileVisible-Light-Mediated Synthesis of Amides from Aldehydes and Amines via in Situ Acid Chloride Formation, Name: 2-Bromopyridin-3-amine, the publication is Journal of Organic Chemistry (2016), 81(5), 1905-1911, database is CAplus and MEDLINE.

An efficient visible-light photocatalysis-based one-pot amide synthesis method was developed; visible-light irradiation of a mixture of an aldehyde, tert-Bu hydrogen peroxide, and N-chlorosuccinimide using a Ru(bpy)₃Cl₂ photocatalyst afforded an acid chloride, which subsequently reacted with amine to yield the corresponding amide. The reaction was used to synthesize moclobemide and a D3 receptor intermediate.

Journal of Organic Chemistry published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Name: 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Chatterjee, Tanmay published the artcileVisible-light-induced regioselective synthesis of polyheteroaromatic compounds, SDS of cas: 39856-58-1, the publication is Chemical Communications (Cambridge, United Kingdom) (2016), 52(22), 4203-4206, database is CAplus and MEDLINE.

A method for visible-light-induced synthesis of polyheteroaroms. e.g., I, from 2-heteroaryl-substituted anilines and heteroarylalkynes was developed. The process, which uses fac-Ir(ppy)₃ as the photocatalyst and tBuONO as the diazotization reagent, is highly regioselective.

Chemical Communications (Cambridge, United Kingdom) published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, SDS of cas: 39856-58-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Mori-Quiroz, Luis M. published the artcileExploiting Iminoquinones as Electrophilic at Nitrogen “N+” Synthons for C-N Bond Construction, HPLC of Formula: 39856-58-1, the publication is Organic Letters (2021), 23(18), 7008-7013, database is CAplus and MEDLINE.

New methods for C-N bond construction exploiting the N-centered electrophilic character of iminoquinones were reported. Iminoquinones, generated in situ via the condensation of o-vinylanilines with benzoquinones, underwent acid-catalyzed cyclization to afford N-arylindoles I [R = H, F; R¹ = H, Me, Ph, etc.; R² = H, Me; R³ = H, Cl, CO₂Me, etc.; Ar = 3,5-di-(t-Bu)-4-OHC₆H₂, 3,5-di-Me-4-OHC₆H₂, 3,5-di-(t-Bu)-2-OHC₆H₂, 10-hydroxy-9-phenanthryl] in excellent yields. Under similar reaction conditions, homoallylic amines reacted analogously to afford N-arylpyrroles II [R⁴ = Ph, 3-MeOC₆H₄, 4-FC₆H₄, 2,6-di-FC₆H₃, 2,3-dihydrobenzofuran-5-yl; R⁵ = H, 4-MeC₆H₄; Ar = 3,5-di-(t-Bu)-4-OHC₆H₂]. Addnl., organometallic nucleophiles were shown to add to the nitrogen atom of N-alkyliminoquinones to provide amine products. Finally, iminoquinones were shown to be competent electrophiles for copper-catalyzed hydroamination.

Organic Letters published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, HPLC of Formula: 39856-58-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Li, Chaomin published the artcileRapid construction of imidazopyridines from ortho-haloaminopyridines, Computed Properties of 39856-58-1, the publication is Tetrahedron Letters (2016), 57(25), 2708-2712, database is CAplus.

A practical strategy for the preparation of imidazopyridine derivatives from ortho-haloaminopyridines using a two-step C-N coupling/cyclization reaction sequence was developed. This procedure provides rapid and efficient access to many medicinally interesting imidazopyridine compounds and related imidazopyrazine/purine heterocycles.

Tetrahedron Letters published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Computed Properties of 39856-58-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Chen, Dongsheng published the artcileOne-Pot Synthesis of Indole-3-acetic Acid Derivatives through the Cascade Tsuji-Trost Reaction and Heck Coupling, COA of Formula: C5H5BrN2, the publication is Journal of Organic Chemistry (2018), 83(12), 6805-6814, database is CAplus and MEDLINE.

A practical palladium-mediated cascade Tsuji-Trost reaction/Heck coupling of N-Ts o-bromoanilines with 4-acetoxy-2-butenoic acid derivatives using a Pd(OAc)2/P(o-tol)3/DIPEA system is described for a straightforward synthesis of indole-3-acetic acid derivs, e.g. I. This methodol. was successfully applied to synthesize various substituted indole/azaindole-3-acetic acid derivatives and Almotriptan, which is a drug for the acute treatment of migraine. Moreover, a plausible cyclization mechanism has been proposed.

Journal of Organic Chemistry published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, COA of Formula: C5H5BrN2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Potkin, V. I. published the artcile5-(Naphth-1-yl)- and 5-[(1,1′-biphenyl)-4-yl]isoxazole-3-carbaldehyde oximes: Synthesis, complexes with palladium, and application in catalysis, Safety of 2-Bromopyridin-3-amine, the publication is Russian Journal of General Chemistry (2014), 84(9), 1782-1792, database is CAplus.

1-(Naphth-1-yl)- and 1-(1,1′-biphenyl)-4-yl-3,4,4-trichloro-3-buten-1-ones were synthesized by acylation of naphthalene and biphenyl with 3,4,4-trichloro-3-butenoyl chloride. Further reaction with hydroxylamine led to 5-(naphth-1-yl)- and 5-[(1,1′-biphenyl)-4-yl]isoxazole-3-carbaldehyde oximes. The latter form complexes with palladium, which possess high catalytic activity in the Suzuki reaction in aqueous and aqueous-alc. media.

Russian Journal of General Chemistry published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Safety of 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lamers, Philip published the artcileBenzo[c]isothiazole 2-Oxides: Three-Dimensional Heterocycles with Cross-Coupling and Functionalization Potential, Name: 2-Bromopyridin-3-amine, the publication is Advanced Synthesis & Catalysis (2016), 358(22), 3649-3653, database is CAplus.

A robust method for the synthesis of benzo[c]isothiazole 2-oxides has been developed providing a range of functionalized derivatives starting from anilines and DMSO. The reaction sequence can be performed on a gram scale and leads to products that can easily be modified by standard cross-coupling reactions.

Advanced Synthesis & Catalysis published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Name: 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lamers, Philip published the artcileTetrahydrobenzo[c]thieno[2,1-e]isothiazole 4-Oxides: Three-Dimensional Heterocycles as Cross-Coupling Building Blocks, Related Products of pyridine-derivatives, the publication is Organic Letters (2018), 20(1), 116-118, database is CAplus and MEDLINE.

Tetrahydrobenzothienoisothiazole oxides such as I (R = H, I, Br, F, Cl, NC, MeO₂C, O₂N, F₅S, F₃C), cyclic sulfoximines, were prepared as novel heterocycles amenable to cross-coupling reactions and automated parallel synthesis. Reaction of tetrahydrothiophene with anilines such as 4-RC₆H₄NH₂ (R = H, I, Br, F, Cl, NC, MeO₂C, O₂N, F₅S, F₃C) mediated by N-chlorosuccinimide (NCS) and Et₃N in CH₂Cl₂ yielded (tetrahydrothienyl)anilines such as II (R = H, I, Br, F, Cl, NC, MeO₂C, O₂N, F₅S, F₃C) in 29-89% yields; tetrahydrothiopyran, N-Boc thiomorpholine, and 1,4-thioxane yielded thioether-substituted anilines, but the products did not undergo oxidative cyclocondensation. Further oxidation of (tetrahydrothienyl)anilines with N-chlorosuccinimide, treatment with aqueous NaOH, and oxidation with meta-chloroperbenzoic acid (mCPBA) yielded such as I (R = H, I, Br, F, Cl, NC, MeO₂C, O₂N, F₅S, F₃C). I (R = I, Br) and related tetrahydrobenzothienoisothiazole oxides underwent borylation, Sonogashira, and Suzuki coupling reactions.

Organic Letters published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Biot, Nicolas published the artcileConcurring Chalcogen- and Halogen-Bonding Interactions in Supramolecular Polymers for Crystal Engineering Applications, Related Products of pyridine-derivatives, the publication is Chemistry – A European Journal (2020), 26(13), 2904-2913, database is CAplus and MEDLINE.

The engineering of crystalline mol. solids through the simultaneous combination of distinctive non-covalent interactions is an important field of research, as it could allow chemist to prepare materials depicting multi-responsive properties. It is in this context that, pushed by a will to expand the chem. space of chalcogen-bonding interactions, a concept is put forward for which chalcogen- and halogen-bonding interactions can be used simultaneously to engineer multicomponent co-crystals. Through the rational design of crystallizable mols., chalcogenazolo pyridine scaffold (CGP) modules were prepared that, bearing either a halogen-bond acceptor or donor at the 2-position, can interact with suitable complementary mol. modules undergoing formation of supramol. polymers at the solid state. The recognition reliability of the CGP moiety to form chalcogen-bonded dimers allows the formation of heteromol. supramol. polymers through halogen-bonding interactions, as confirmed by single-crystal X-ray diffraction anal.

Chemistry – A European Journal published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Biot, Nicolas published the artcileProgramming Recognition Arrays through Double Chalcogen-Bonding Interactions, Safety of 2-Bromopyridin-3-amine, the publication is Chemistry – A European Journal (2018), 24(21), 5439-5443, database is CAplus and MEDLINE.

In this work, we have programmed and synthesized a recognition motif constructed around a chalcogenazolo-pyridine scaffold (CGP) that, through the formation of frontal double chalcogen-bonding interactions, associates into dimeric EX-type complexes. The reliability of the double chalcogen-bonding interaction has been shown at the solid-state by X-ray anal., depicting the strongest recognition persistence for a Te-congener. The high recognition fidelity, chem. and thermal stability and easy derivatization at the 2-position makes CGP a convenient motif for constructing supramol. architectures through programmed chalcogen-bonding interactions.

Chemistry – A European Journal published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Safety of 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem