Category: 500-22-1

Name: 3-Pyridinecarboxaldehyde. I found the field of Chemistry very interesting. Saw the article 2-Hydroxyethyl-1-ammonium 3-hydroxypropane-1-sulfonate: a biodegradable and recyclable ionic liquid for the one-pot synthesis of 2-amino-3-cyano-4H-pyrans published in 2019.0, Reprint Addresses Honarmand, M (corresponding author), Birjand Univ Technol, Fac Min Civil & Chem Engn, Dept Chem Engn, Birjand 97175569, Iran.. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde.

2-Hydroxyethyl-1-ammonium 3-hydroxypropane-1-sulfonate HAHS’ was synthesized as a novel ionic liquid and characterized by various techniques. HAHS’ ionic liquid was efficiently applied as a multifunctional promoter for the three-component synthesis of 2-amino-3-cyano-4H-pyrans. The 2-amino-3-cyano-4H-pyrans were produced not only in high to excellent yields but also no toxic solvent or catalyst was used. HAHS’ ionic liquid was recovered and reused four times without the considerable decreasing in its activity. The effect of hydroxyl groups in the structure of HAHS’ ionic liquid on its catalytic activity was studied. Moreover, the biodegradability potential of the ionic liquid was examined using the 5-day biological oxygen demand closed bottle test and the results showed that HAHS’ has remarkable biodegradability potential.

Name: 3-Pyridinecarboxaldehyde. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Honarmand, M; Tzani, A; Detsi, A or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Light and oxygen-enabled sodium trifluoromethanesulfinate-mediated selective oxidation of C-H bonds WOS:000545862800029 published article about PHOTOREDOX CATALYSIS; CARBOXYLIC-ACIDS; TRIFLUOROMETHYLATION; ACTIVATION; ALCOHOLS; ALKYLATION; ALDEHYDES; CLEAVAGE; ESTERS in [Zhu, Xianjin; Liu, Yong; Liu, Can; Yang, Haijun; Fu, Hua] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing 100084, Peoples R China in 2020, Cited 59. Quality Control of 3-Pyridinecarboxaldehyde. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1

Visible light-induced organic reactions are important chemical transformations in organic chemistry, and their efficiency highly depends on suitable photocatalysts. However, the commonly used photocatalysts are precious transition-metal complexes and elaborate organic dyes, which hamper large-scale production due to high cost. Here, for the first time, we report a novel strategy: light and oxygen-enabled sodium trifluoromethanesulfinate-mediated selective oxidation of C-H bonds, allowing high-value-added aromatic ketones and carboxylic acids to be easily prepared in high-to-excellent yields using readily available alkyl arenes, methyl arenes and aldehydes as materials. The mechanistic investigations showed that the treatment of inexpensive and readily available sodium trifluoromethanesulfinate with oxygen under irradiation of light couldin situform a pentacoordinate sulfide intermediate as an efficient photosensitizer. The method represents a highly efficient, economical and environmentally friendly strategy, and the light and oxygen-enabled sodium trifluoromethanesulfinate photocatalytic system represents a breakthrough in photochemistry.

About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Zhu, XJ; Liu, Y; Liu, C; Yang, HJ; Fu, H or concate me.. Quality Control of 3-Pyridinecarboxaldehyde

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Computed Properties of C6H5NO. In 2020 J HETEROCYCLIC CHEM published article about FLUORESCENCE in [Horak, Radim; Koristek, Kamil; Samsulova, Veronika; Slaninova, Ludmila; Grepl, Martin; Kvapil, Lubomir; Funk, Petr; Hradil, Pavel; Soural, Miroslav] Palacky Univ, Dept Organ Chem, Fac Sci, 17 Listopadu, Olomouc, Czech Republic in 2020, Cited 37. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1.

Compounds bearing [1,3]dioxolo-quinoline scaffolds have been found in quinoline-based natural products; the only exception is the [1,3]dioxolo[4,5-c]quinoline moiety with a rare occurrence in both natural and synthetic derivatives. In this article, we report the preparation of diversely substituted and functionalized [1,3]dioxolo[4,5-c]quinolines using [1,3]dioxolo[4,5-c]quinoline-4-carbaldehyde (DQC) as the common intermediate. DQC was synthesized on a large scale from anthranilic acid and chloroacetone as the starting materials, with the rearrangement of acetonyl-anthranilate as the key step. The developed method allows for the simple preparation of [1,3]dioxolo[4,5-c]quinolines with various C2 substituents on the quinoline scaffold. Additionally, the synthetic route was successfully applied to the preparation of 3-hydroxyquinoline-4(1H)-ones. The target compounds were tested against representative Gram-positive/negative bacteria, and two derivatives exhibited submicromolar minimum inhibitory concentrations against Micrococcus luteus.

Computed Properties of C6H5NO. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Horak, R; Koristek, K; Samsulova, V; Slaninova, L; Grepl, M; Kvapil, L; Funk, P; Hradil, P; Soural, M or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

I found the field of Chemistry very interesting. Saw the article Umpolung Difunctionalization of Carbonyls via Visible-Light Photoredox Catalytic Radical-Carbanion Relay published in 2020.0. SDS of cas: 500-22-1, Reprint Addresses Konig, B (corresponding author), Univ Regensburg, Fac Chem & Pharm, Inst Organ Chem, D-93040 Regensburg, Germany.. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde

The combination of photoredox catalysis with the Wolff-Kishner (WK) reaction allows the difunctionalization of carbonyl groups by a radical-carbanion relay sequence (photo-Wolff-Kishner reaction). Photoredox initiated radical addition to N-sulfonylhydrazones yields alpha-functionalized carbanions following the WK-type mechanism. With sulfur-centered radicals, the carbanions are further functionalized by reaction with electrophiles including CO2 and aldehydes, whereas CF3 radical addition furnishes a wide range of gem-difluoroalkenes through beta-fluoride elimination of the generated alpha-CF3 carbanions. More than 80 substrate examples demonstrate the broad applicability of this reaction sequence. A series of investigations including radical inhibition, deuterium labeling, fluorescence quenching, cyclic voltammetry, and control experiments support the proposed radical-carbanion relay mechanism.

About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Wang, S; Cheng, BY; Srsen, M; Konig, B or concate me.. SDS of cas: 500-22-1

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Ramu, S; Srinath, S; Kumar, AA; Baskar, B; Ilango, K; Balasubramanian, KK in [Ramu, S.; Srinath, S.; Kumar, A. Aswin; Baskar, B.] SRM Inst Sci & Technol, Dept Chem, Lab Sustainable Chem, Kattankulatur 603203, Tamil Nadu, India; [Ilango, K.] SRM Inst Sci & Technol, IIISM, Kattankulathur 603203, Tamil Nadu, India; [Ilango, K.] SRM Inst Sci & Technol, SRM Coll Pharm, Dept Pharmaceut Chem, Kattankulathur 603203, Tamil Nadu, India; [Balasubramanian, K. K.] Indian Inst Technol Madras, Dept Biotechnol, Chennai 600036, Tamil Nadu, India published Metal free one pot synthesis of beta-carbolines via a domino Pictet-Spengler reaction and aromatization in 2019.0, Cited 79.0. Formula: C6H5NO. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1.

A convenient and efficient metal free, atom economical flexible synthesis of beta-carbolines involving a domino Pictet-Spengler reaction and aromatization in oxygen atmosphere in N-methyl-2-pyrollidone (NMP) is described. Variety of aryl, heteroaryl and aliphatic aldehydes were found to be good substrates for this methodology. Several beta-carbolines (6a-6t) and beta-carboline methyl esters (7a-7e) were synthesized using this methodology. The same reaction carried out in argon atmosphere in the presence of catalytic amount of acid in NMP furnished, tetrahydro-beta-carbolines (4a-4g).

About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Ramu, S; Srinath, S; Kumar, AA; Baskar, B; Ilango, K; Balasubramanian, KK or concate me.. Formula: C6H5NO

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Name: 3-Pyridinecarboxaldehyde. Siddiqui, IR; Neha, S; Waseem, MA; Sagir, H in [Siddiqui, I. R.; Neha, Shamshun; Waseem, Malik Abdul; Sagir, Hozeyfa] Univ Allahabad, Dept Chem, Lab Green Synth, Allahabad 211002, Uttar Pradesh, India published Aqua mediated multicomponent reaction under phase transfer catalysis: A novel and green approach to access fused pyrazoles in 2019.0, Cited 71.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1.

An environmentally benign multicomponent strategy for the synthesis of fused pyrazole derivatives has been developed. The present strategy provides a rapid access to construct a diversity-oriented library of fused pyrazoles by using three simple and readily available substrates viz. aromatic aldehyde, tetronic acid and aryl hydrazine as amine source. Further, the employment of molecular iodine, phase transfer catalyst and water altogether served as a green attribute to the present protocol. (C) 2015 The Authors. Published by Elsevier B.V. on behalf of King Saud University.

Name: 3-Pyridinecarboxaldehyde. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Siddiqui, IR; Neha, S; Waseem, MA; Sagir, H or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

HPLC of Formula: C6H5NO. In 2020.0 MOLECULES published article about BIOLOGICAL EVALUATION; MOLECULAR DOCKING; CRYSTAL-STRUCTURE; PYRAZOLINES; ANTICANCER; ANTIBACTERIAL; ANALOGS in [Shaik, Afzal B.] Jawaharlal Nehru Technol Univ, Vignan Pharm Coll, Dept Pharmaceut Chem, Vadlamudi 522213, India; [Bhandare, Richie R.; Edis, Zehra] Ajman Univ, Coll Pharm & Hlth Sci, Dept Pharmaceut Sci, POB 346, Ajman, U Arab Emirates; [Tangirala, N. Ravikiran] Jawaharlal Nehru Technol Univ, Narasaraopeta Inst Pharmaceut Sci, Dept Pharmaceut Chem, Narsaraopet 522601, India; [Shahanaaz, Shaik] Victoria Coll Pharm, Dept Pharmaceut Chem, Nallapadu 522001, India; [Rahman, M. Mukhlesur] Univ East London, Sch Hlth Sports & Biosci, Med Res Grp, Stratford Campus,Water Lane, London E15 4LZ, England in 2020.0, Cited 47.0. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1.

Infectious diseases caused by fungi and mycobacteria pose an important problem for humankind. Similarly, cancer is one of the leading causes of death globally. Therefore, there is an urgent need for the development of novel agents to combat the deadly problems of cancer, tuberculosis, and also fungal infections. Hence, in the present study, we designed, synthesized, and characterized 30 compounds including 15 chalcones (2-16) and 15 dihydropyrazoles (17-31) containing dichlorophenyl moiety and also screened these compounds for their antifungal, antitubercular, and antiproliferative activities. Among these compounds, the dihydropyrazoles showed excellent antifungal and antitubercular activities whereas the chalcones exhibited promising antiproliferative activity. Among the dihydropyrazoles, compound31containing 2-thienyl moiety showed promising antifungal activity (MIC 5.35 mu M), whereas compounds22and24containing 2,4-difluorophenyl and 4-trifluoromethyl scaffolds revealed significant antitubercular activity with the MICs of 3.96 and 3.67 mu M, respectively. Compound16containing 2-thienyl moiety in the chalcone series showed the highest anti-proliferative activity with an IC(50)value of 17 +/- 1 mu M. The most active compounds identified through this study could be considered as starting points in the development of drugs with potential antifungal, antitubercular, and antiproliferative activities.

HPLC of Formula: C6H5NO. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Shaik, AB; Bhandare, RR; Nissankararao, S; Edis, Z; Tangirala, NR; Shahanaaz, S; Rahman, MM or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Product Details of 500-22-1. Leijendekker, LH; Weweler, J; Leuther, TM; Kratz, D; Streuff, J in [Leijendekker, Leonardus H.; Weweler, Jens; Leuther, Tobias M.; Streuff, Jan] Albert Ludwigs Univ Freiburg, Inst Organ Chem, Albertstr 21, D-79104 Freiburg, Germany; [Kratz, Daniel] Albert Ludwigs Univ Freiburg, Inst Anorgan & Analyt Chem, Albertstr 21, D-79104 Freiburg, Germany published Development, Scope, and Applications of Titanium(III)-Catalyzed Cyclizations to Aminated N-Heterocycles in 2019, Cited 121. The Name is 3-Pyridinecarboxaldehyde. Through research, I have a further understanding and discovery of 500-22-1.

The exceptionally mild conditions of a titanium(III)-catalyzed cyclization reaction paired with a convenient acid/base extraction have enabled the straightforward synthesis, isolation, and direct N-functionalization of amino heterocycles such as 3-aminoindoles and -pyrroles. The unprotected heterocycles are ideal building blocks for the installation of aminated indoles and pyrroles into target molecules, but their sensitivity has previously impeded their synthesis by modern catalytic methods. This full paper presents the development and extended scope of the new cyclization methodology. The transformation of the products into fused bis-indoles is also demonstrated along with the discovery of an unusual palladium-catalyzed reductive biphenyl coupling reaction. The titanium(III)-catalyzed cyclization has also been applied to the synthesis of substituted 3-iminoindolines, which are of potential interest for applications in natural product synthesis and exhibit tunable blue-to-green fluorescence properties.

About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Leijendekker, LH; Weweler, J; Leuther, TM; Kratz, D; Streuff, J or concate me.. Product Details of 500-22-1

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Quality Control of 3-Pyridinecarboxaldehyde. Recently I am researching about SOLVENT-FREE HYDROBORATION; COMPLEXES SYNTHESES; MAGNESIUM, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21772093]; Natural Science Foundation of Jiangsu Province, ChinaNatural Science Foundation of Jiangsu Province [BK20181421]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Wang, WF; Lu, K; Qin, Y; Yao, WW; Yuan, DD; Pullarkat, SA; Xu, L; Ma, MT. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde

Simple, commercially available Grignard reagents have been used as highly efficient precatalysts for the hydroboration of a wide range of aldehydes and ketones. The reaction employs very low catalyst loadings (aldehydes: 0.05 mol%, ketones: 0.5 mol%), and proceeds rapidly (aldehydes: 10 min, ketones: 20 min) under neat condition at room temperature. The Grignard reagent catalyst demonstrated good substrate scope, functional group tolerance, and high chemoselectivity in the carbonyl hydroboration. DFT calculations were performed to investigate the possible reaction mechanism. In contrast to the traditional stoichiometric use of Grignard reagents, this newly developed protocol provides a catalytic application of these reagents for molecular transformations. (C) 2020 Elsevier Ltd. All rights reserved.

Quality Control of 3-Pyridinecarboxaldehyde. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Wang, WF; Lu, K; Qin, Y; Yao, WW; Yuan, DD; Pullarkat, SA; Xu, L; Ma, MT or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Formula: C6H5NO. I found the field of Chemistry very interesting. Saw the article A Ba/Pd Catalytic System Enables Dehydrative Cross-Coupling and Excellent E-Selective Wittig Reactions published in 2019.0, Reprint Addresses Xie, PZ; Loh, TP (corresponding author), Nanjing Tech Univ, Sch Chem & Mol Engn, Inst Adv Synth, Nanjing 211816, Jiangsu, Peoples R China.; Loh, TP (corresponding author), Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore.. The CAS is 500-22-1. Through research, I have a further understanding and discovery of 3-Pyridinecarboxaldehyde.

A Ba/Pd cooperative catalysis system was developed to enable the dehydrative cross-coupling of allylic alcohols with P-ylides to occur directly and promote a subsequent Wittig reaction in one pot. A variety of multisubstituted 1,4-dienes were isolated in good to excellent yields with broad P-ylides (stabilized by both ester and ketone carbonyl groups) and aldehyde (aliphatic and aromatic) substrates with excellent E selectivity.

Formula: C6H5NO. About 3-Pyridinecarboxaldehyde, If you have any questions, you can contact Xie, PZ; Fu, WS; Cai, XY; Sun, ZL; Wu, Y; Li, SS; Gao, CQ; Yang, XB; Loh, TP or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem