Category: 505084-55-9

Simple exploration of 505084-55-9

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 505084-55-9, 2-Chloro-5-(trifluoromethyl)-4-iodopyridine.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 505084-55-9, name is 2-Chloro-5-(trifluoromethyl)-4-iodopyridine. A new synthetic method of this compound is introduced below., category: pyridine-derivatives

Example 21; 5-(2-(2-methoxy-4-morpholinophenylamino)-5-(trifluoromethyl)pyridin-4- ylamino)-N-methylthiazole-4- carboxamide; 2-chloro-5-(trifluoromethyl)pyridin-4-amine; 2-chloro-4-iodo-5-(trifluoromethyl)pyridine was dissolved in 7 M Ammonia/Methanol. It was heated in a Biotage Initiator microwave synthesizer at 130 C for 1 h. A mixture of the 2- and 4-substituted products was obtained. The solvent was removed and the residue was purified by silica gel chromatography (DCM/MeOH) gradient. The pure title compound was isolated.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 505084-55-9, 2-Chloro-5-(trifluoromethyl)-4-iodopyridine.

Reference:
Patent; THE SCRIPPS RESEARCH INSTITUTE; WO2008/115369; (2008); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem