Category: 58327-75-6

Reference of 58327-75-6, Adding some certain compound to certain chemical reactions, such as: 58327-75-6, name is 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid,molecular formula is C8H6N2O2S, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 58327-75-6.

General procedure: To the solution of appropriate 2-aminobenzoic acid in dried THF or 1,4- dioxane was added triphosgene (0.35 eq). The mixture was stirred under reflux for 4-8 hrs. Then the solvent was removed in vacuo to give the isotaic anhydride as a solid in theoretical yield. 1H NMR indicated the product was of sufficient purity and was used in the next step without further purification.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 58327-75-6, 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Huang, Guozheng; Roos, Dominika; Stadtmueller, Patricia; Decker, Michael; Tetrahedron Letters; vol. 55; 26; (2014); p. 3607 – 3609;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Reference of 58327-75-6, Adding some certain compound to certain chemical reactions, such as: 58327-75-6, name is 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid,molecular formula is C8H6N2O2S, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 58327-75-6.

General procedure: To the solution of appropriate 2-aminobenzoic acid in dried THF or 1,4- dioxane was added triphosgene (0.35 eq). The mixture was stirred under reflux for 4-8 hrs. Then the solvent was removed in vacuo to give the isotaic anhydride as a solid in theoretical yield. 1H NMR indicated the product was of sufficient purity and was used in the next step without further purification.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 58327-75-6, 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Huang, Guozheng; Roos, Dominika; Stadtmueller, Patricia; Decker, Michael; Tetrahedron Letters; vol. 55; 26; (2014); p. 3607 – 3609;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 58327-75-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 58327-75-6, name is 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid, molecular formula is C8H6N2O2S, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

A solution of 238 (17 g, 87 mmoi) in phosphoc acid (150 mL, 85% aqueous solution) is stirred at 100 C for 45 minutes. Saturated aqueous sodium bicarbonate solution is then added at room temperature to adjust to pH 8. The solid is collected by filtration and washed with EtOH (100 mL x 2) to give US as an orange solid (9.0 g, 54% yield). (MS:[M+H] 152.1)

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 58327-75-6, 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid.

Reference:
Patent; IMMUNE SENSOR, LLC; THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM; ZHONG, Boyu; SUN, Lijun; SHI, Heping; LI, Jing; CHEN, Chuo; CHEN, Zhijian; (270 pag.)WO2017/176812; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 58327-75-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 58327-75-6, name is 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid, molecular formula is C8H6N2O2S, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

A solution of 238 (17 g, 87 mmoi) in phosphoc acid (150 mL, 85% aqueous solution) is stirred at 100 C for 45 minutes. Saturated aqueous sodium bicarbonate solution is then added at room temperature to adjust to pH 8. The solid is collected by filtration and washed with EtOH (100 mL x 2) to give US as an orange solid (9.0 g, 54% yield). (MS:[M+H] 152.1)

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 58327-75-6, 3-Aminothieno[2,3-b]pyridine-2-carboxylic acid.

Reference:
Patent; IMMUNE SENSOR, LLC; THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM; ZHONG, Boyu; SUN, Lijun; SHI, Heping; LI, Jing; CHEN, Chuo; CHEN, Zhijian; (270 pag.)WO2017/176812; (2017); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem