Category: 70411-83-5

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 70411-83-5, name is 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile, the common compound, a new synthetic route is introduced below. name: 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile

[0151] To a stirred solution of compound 11(1.67 g; 11.9 mmol; 1 eq) in methanol (80 mL) was added concentrated HC1 (1 mL) followed by 10% Pd/C (1.6 g) and the resulting mixture was stirred under hydrogen atmosphere at a pressure of 50 psi for 4 h in a Parr autoclave. The mixture was filtered through a Celite bed, washed with methanol and solvent of the filtrate was removed in vacuo to obtain the title compound (2 g, 92%). 1H NMR (DMSO-d6) oe 8.55 (brs, iH), 7.72 (d, iH, J= 7Hz), 6.46 (s, iH), 6.31 (dd, iH, J= 2,7 Hz,), 3.86 (m, 2H), 3.40 (s, 3H).

The synthetic route of 70411-83-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ASANA BIOSCIENCES, LLC; THOMPSON, Scott; VENKATESAN, Aranapakam; PRIESTLEY, Tony; KUNDU, Mrinal; SAHA, Ashis; WO2015/95128; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 70411-83-5, name is 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile, the common compound, a new synthetic route is introduced below. name: 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile

[0151] To a stirred solution of compound 11(1.67 g; 11.9 mmol; 1 eq) in methanol (80 mL) was added concentrated HC1 (1 mL) followed by 10% Pd/C (1.6 g) and the resulting mixture was stirred under hydrogen atmosphere at a pressure of 50 psi for 4 h in a Parr autoclave. The mixture was filtered through a Celite bed, washed with methanol and solvent of the filtrate was removed in vacuo to obtain the title compound (2 g, 92%). 1H NMR (DMSO-d6) oe 8.55 (brs, iH), 7.72 (d, iH, J= 7Hz), 6.46 (s, iH), 6.31 (dd, iH, J= 2,7 Hz,), 3.86 (m, 2H), 3.40 (s, 3H).

The synthetic route of 70411-83-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ASANA BIOSCIENCES, LLC; THOMPSON, Scott; VENKATESAN, Aranapakam; PRIESTLEY, Tony; KUNDU, Mrinal; SAHA, Ashis; WO2015/95128; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 70411-83-5, name is 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 70411-83-5

1- Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile (302 mg), it was heated under reflux for 3 hours a mixture of 50% hydroxylamine aqueous solution (160 muL) and ethanol (2.0 mL). The reaction mixture wasconcentrated under reduced pressure to give the title compound (366 mg) as a colorless solid.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 70411-83-5, 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile.

Reference:
Patent; TAISHO PHARMACEUTICAL COMPANY LIMITED; KONISHI, KAZUHIDE; KANUMA, KOSUKE; NAKAMURA, TOSHIO; AMADA, HIDEAKI; YAMAMOTO, SHUJI; KASHIWA, SHUHEI; MASUDA, SEIJI; OKADA, KUMIKO; KAWAMOTO, HIROSHI; (74 pag.)JP2015/78127; (2015); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 70411-83-5, name is 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 70411-83-5

1- Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile (302 mg), it was heated under reflux for 3 hours a mixture of 50% hydroxylamine aqueous solution (160 muL) and ethanol (2.0 mL). The reaction mixture wasconcentrated under reduced pressure to give the title compound (366 mg) as a colorless solid.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 70411-83-5, 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile.

Reference:
Patent; TAISHO PHARMACEUTICAL COMPANY LIMITED; KONISHI, KAZUHIDE; KANUMA, KOSUKE; NAKAMURA, TOSHIO; AMADA, HIDEAKI; YAMAMOTO, SHUJI; KASHIWA, SHUHEI; MASUDA, SEIJI; OKADA, KUMIKO; KAWAMOTO, HIROSHI; (74 pag.)JP2015/78127; (2015); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 70411-83-5, name is 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 70411-83-5

1- Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile (302 mg), it was heated under reflux for 3 hours a mixture of 50% hydroxylamine aqueous solution (160 muL) and ethanol (2.0 mL). The reaction mixture wasconcentrated under reduced pressure to give the title compound (366 mg) as a colorless solid.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 70411-83-5, 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile.

Reference:
Patent; TAISHO PHARMACEUTICAL COMPANY LIMITED; KONISHI, KAZUHIDE; KANUMA, KOSUKE; NAKAMURA, TOSHIO; AMADA, HIDEAKI; YAMAMOTO, SHUJI; KASHIWA, SHUHEI; MASUDA, SEIJI; OKADA, KUMIKO; KAWAMOTO, HIROSHI; (74 pag.)JP2015/78127; (2015); A;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem