Application of 874-80-6 ,Some common heterocyclic compound, 874-80-6, molecular formula is C9H14BrN, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: Tributyltetradecylphosphonium bis(trifluoromethylsulfonyl)imide [P44414][NTf2] (1); 1-butyl-2,3-dimethylimidazolium bis(trifluoromethylsulfonyl)imide [BMMIM][NTf2] (3); 1-butylpyridiniumbis(trifluoromethylsulfonyl)imide [BuPy][NTf2] (2); 1-allylpyridinium bis(trifluoromethylsulfonyl)imide[AllPy][NTf2] (5); 1-allyl-2,3-dimethylimidazoliumbis(trifluoromethylsulfonyl)imide [AlldiMIM][NTf2] (7)and 1,3-diallyl-2-methylimiidazolium bis(trifluoromethylsulfonyl)imide [diAllMIM][NTf2] (6) weresynthesized by metathesis reaction using the general procedure:Pyridinium or imidazolium halide (bromide or chloride) was dissolved in water and it wastransferred to a separator funnel with dichloromethane. Subsequently, 1.1 molar equivalent of LiNTf2(80% solution in water) was added and a separator funnel was shaken vigorously. After phaseseparation, the organic phase was washed twice with water, once with 5% water solution of LiNTf2,and this procedure was repeated until water phase was completely free of halide anion. To confirmabsence of chloride anion, acidic solution of silver nitrate was added to a sample of water phase. Noprecipitate of silver chloride indicated an absence of chloride anion. Subsequently, the organic phasewas separated, evaporated and dried under high vacuum (1 mbar) in 60 C for 24 h. The structure ofobtained salts were confirmed by 1H-NMR analysis.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 874-80-6, N-butylpyridinium bromide, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Zielinski, Witold; Kukawka, Rafal; Maciejewski, Hieronim; Smiglak, Marcin; Molecules; vol. 21; 9; (2016);,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem