Synthetic Route of 886373-00-8, Adding some certain compound to certain chemical reactions, such as: 886373-00-8, name is 5-Bromo-2-ethoxypyridin-3-amine,molecular formula is C7H9BrN2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 886373-00-8.
Intermediate 61 lambda/-[5-Bromo-2-(ethyloxy)-3-pyridinyl]benzenesulfonamide A solution of 5-bromo-2-(ethyloxy)-3-pyridinamine (1.45 g) in anhydrous pyridine (15 ml) was treated with benzenesulfonyl chloride (1.03 ml) then stirred at RT for 20 hr. The reaction was evaporated to dryness and the residue was purified by column chromatography on silica, eluting with 30% hexanes in DCM, to give the title compound (1.86 g).1H NMR: deltaH (DMSOd6, 400 MHz) 10.09 (1 H, s), 8.03 (1 H, d), 7.74 (1 H, d), 7.71 (1 H, d), 7.64 (1 H, d), 7.57 (2H, d), 4.05 (2H, q), 1.07 (3H, t).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 886373-00-8, 5-Bromo-2-ethoxypyridin-3-amine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; GLAXO GROUP LIMITED; WO2009/147187; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem