Category: 91-02-1

Safety of Phenyl(pyridin-2-yl)methanone. Chen, S; Hou, P; Sun, JW; Wang, HJ; Liu, L in [Chen, Song; Hou, Peng; Sun, Jingwen; Wang, Haijun; Liu, Lei] Qiqihar Med Univ, Coll Pharm, 333 Bukui St, Qiqihar 161006, Heilongjiang, Peoples R China published Imidazo[1,5-alpha]pyridine-based fluorescent probe with a large Stokes shift for specific recognition of sulfite in 2020.0, Cited 35.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

By taking advantage of the intramolecular charge transfer (ICT) process, we presented a novel fluorescent probe IPY-SO2 based on imidazo[1,5-alpha]pyridine derivative for detecting SO32- with a low detection limit (70 nM). Combining its favorable turn-on fluorescence feature (75-fold), rapid response (5 min), high selectivity, large Stokes shift (174 nm) and low cytotoxicity, IPY-SO2 was successfully applied to imaging SO32 in living MCF-7 cells and zebrafish. (C) 2019 Elsevier B.V. All rights reserved.

Safety of Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Chen, S; Hou, P; Sun, JW; Wang, HJ; Liu, L or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Formula: C12H9NO. I found the field of Chemistry; Crystallography very interesting. Saw the article Structurally characterized mononuclear isostructural Ni(II), Cu(II) and Zn (II) complexes as a functional model for phenoxazinone synthase activity published in 2019.0, Reprint Addresses Ghosh, R (corresponding author), Univ Burdwan, Dept Chem, Burdwan 713104, W Bengal, India.. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone.

Three new mononuclear complexes of the type [M(L)(2)](ClO4)(2), with Ni(II) (1), Cu(II) (2) and Zn(II) (3) ions, have been synthesized and structurally characterized, using the N,N,O donor Schiff base ligand 2-[(phenyl-pyridine-2-yl-methylene)-amino]-ethanol]. An X-ray diffraction study reveals identical crystallization patterns for each of the complexes, in the monoclinic crystal system with the C2/c space group. Interestingly, the synthesized complexes are isostructural in nature. The complexes showed biomimetic phenoxazinone synthase-like activity for the aerial oxidation of o-aminophenol to phenoxazine-2-one, separately in methanol (MeOH) and acetonitrile (ACN) solutions. For each of the complexes, the turnover numbers were found to be higher in MeOH than in ACN. The highest catalytic activity between among the three complexes was found to be for complex 2. (C) 2019 Elsevier Ltd. All rights reserved.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Chatterjee, A; Khan, S; Ghosh, R or concate me.. Formula: C12H9NO

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recently I am researching about LARGE STOKES SHIFT; TURN-ON PROBE; CELLULAR THIOLS; LIVING CELLS; REDOX; HOMOCYSTEINE; CONJUGATE; HYDRAZINE; APOPTOSIS; ROLES, Saw an article supported by the Natural Science Foundation of Heilongjiang Province of ChinaNatural Science Foundation of Heilongjiang Province [LH2019B033]. Published in ELSEVIER SCIENCE SA in LAUSANNE ,Authors: Hou, P; Sun, JW; Wang, HJ; Liu, L; Zou, LW; Chen, S. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone. HPLC of Formula: C12H9NO

A novel fluorescent probe, TCF-IPY, has been designed and developed for highly selective and ratiometric detection of GSH based on the extend of the pi-conjugation system of imidazo[1,5-alpha]pyridine IPY-CHO. Upon addition of GSH, TCF-IPY displayed remarkable fluorescence variations (approximate 949-fold ratio changes) from 603 nm to 475 nm, thereby enabling GSH detection in a fine ratiometric manner. Moreover, TCF-IPY exhibited excellent selectivity toward GSH over other biologically related species including Cys and Hcy. The huge blue shifts both in absorption (259 nm) and emission spectra (128 nm), low cytotoxicity, high sensitivity (97 nM) and rapid response (240 s) of TCF-IPY make it a robust molecular tool for endogenous GSH investigation. Furthermore, TCF-IPY was also successfully used for ratiometric imaging of endogenous GSH in living MCF-7 cells and zebrafish.

HPLC of Formula: C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Hou, P; Sun, JW; Wang, HJ; Liu, L; Zou, LW; Chen, S or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Computed Properties of C12H9NO. In 2021 TETRAHEDRON LETT published article about SELECTIVE OXIDATION; N-BROMOSUCCINIMIDE; SULFATED POLYBORATE; BENZYLIC ALCOHOLS; EFFICIENT; CATALYST; ALDEHYDES; COMPLEX; DERIVATIVES; WATER in [Palav, Amey; Misal, Balu; Ganwir, Prerna; Chaturbhuj, Ganesh] Inst Chem Technol, Mumbai 400019, Maharashtra, India; [Palav, Amey; Misal, Balu] Loba Chem Pvt Ltd, Res & Dev Ctr, Tarapur 401506, Thane, India; [Badani, Purav] Univ Mumbai, Dept Chem, Mumbai 400098, Maharashtra, India in 2021, Cited 42. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

Chlorine is the 20th most abundant element on the earth compared to bromine, iodine, and fluorine, a sulfonimide reagent, N-chloro-N-(phenylsulfonyl)benzenesulfonamide (NCBSI) was identified as a mild and selective oxidant. Without activation, the reagent was proved to oxidize primary and secondary alcohols as well as their symmetrical and mixed ethers to corresponding aldehydes and ketones. With recoverable PS-TEMPO catalyst, selective oxidation over chlorination of primary and secondary alcohols and their ethers with electron-donating substituents was achieved. The reagent precursor of NCBSI was recovered quantitatively and can be reused for synthesizing NCBSI. (C) 2021 Elsevier Ltd. All rights reserved.

Computed Properties of C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Palav, A; Misal, B; Ganwir, P; Badani, P; Chaturbhuj, G or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Quality Control of Phenyl(pyridin-2-yl)methanone. In 2019.0 J MOL STRUCT published article about CRYSTAL-STRUCTURE; SPECTROSCOPIC CHARACTERIZATION; INTERMOLECULAR INTERACTIONS; ANTIBACTERIAL ACTIVITY; COORDINATION BEHAVIOR; BIOLOGICAL-ACTIVITY; CHEMICAL ACTIVITY; DIAZO-COMPOUNDS; SCHIFF-BASES; X-RAY in [Cinarli, Murat] Ahi Evran Univ, Cent Res & Applicat Lab, TR-40100 Kirsehir, Turkey; [Cinarli, Esra] Ahi Evran Univ, Fac Sci, Dept Biol, TR-40100 Kirsehir, Turkey; [Ataol, Cigdem Yuksektepe] Cankiri Karatekin Univ, Fac Sci, Dept Phys, TR-18100 Cankiri, Turkey; [Idil, Onder] Amasya Univ, Fac Educ, Dept Basic Educ, TR-05000 Amasya, Turkey; [Kariptas, Ergin] Ahi Evran Univ, Fac Med, Dept Microbiol, TR-40100 Kirsehir, Turkey in 2019.0, Cited 65.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

The NNO tridentate Schiff base ligand of 2-benzoyl pyridine sulfonyl hydrazone (HL) and its transition metal complexes [CoL2] (1), [NiL2] (2) and [ZnL2] (3) have been synthesized and characterized by analytical and spectroscopic studies. The molecular structures of HL and [NiL2] (2) have been investigated by X-ray diffraction and DET/B3LYP methods. Based on the optimized structures, a single point energy calculation was made for HL and (2) in the different solvent media. The stability of the molecular structures was investigated in different solvent environments by calculating the molecular orbital energies and total energies of the molecular structures. The global reactivity parameters were obtained and the interactions between the molecules with DNA bases such as adenine, cytosine, guanine, and thymine were investigated by using the ECT (electrophilicity-based charge transfer) method and Delta N (charge transfer). Hirshfeld surfaces of HL and (2) complex were investigated and the interaction energies between the molecules participating in C-H center dot center dot center dot O/pi interactions in the molecular structures were calculated by using the CE-HF energy model. From elemental analysis data, the metal-ligand ratio of the complexes was found to be 1:2. All compounds were examined for their antimicrobial activity against pathogenic microorganisms by the well-diffusion method. DNA cleavage studies of compounds were screened by the agarose gel electrophoresis method. The results showed that complex (3) showed highly nicking activity, while HL, (1) and (2) complexes didn’t show any nicking activity. (C) 2019 Elsevier B.V. All rights reserved.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Cinarli, M; Cinarli, E; Ataol, CY; Idil, O; Kariptas, E or concate me.. Quality Control of Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article TBAB-Catalyzed Csp(3)-N Bond Formation by Coupling Pyridotriazoles with Anilines: A New Route to (2-Pyridyl)alkylamines WOS:000466513300004 published article about SELECTIVE REDUCTIVE AMINATION; DENITROGENATIVE TRANSANNULATION; N-TOSYLHYDRAZONES; AMINES SYNTHESIS; HYDRAZONES; REAGENTS in [Lamaa, Diana; Lin, Hsin-Ping; Bzeih, Tourin; Alami, Mouad; Hamze, Abdallah] Univ Paris Saclay, Univ Paris Sud, CNRS, BioCIS,Equipe Labellisee Ligue Canc, F-92290 Chatenay Malabry, France; [Retailleau, Pascal] CNRS, Inst Chim Subst Nat, UPR 2301, F-91198 Gif Sur Yvette, France in 2019.0, Cited 52.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. COA of Formula: C12H9NO

A new metal-free procedure allowing Csp(3)-N bond formation through coupling of pyridotriazoles and weakly nucleophilic anilines has been developed. This sustainable reaction shows high tolerance towards functional groups (ketones, free alcohols) leading to 2-picolylamine derivatives. The key to our success is the use of a catalytic amount of TBAB and water as a co-solvent leading to the formation of pyridylalkylamine derivatives. As this coupling tolerates the presence of Csp(2)-Br bond on both partners of the reaction, we performed a sequential one-pot reaction between functionalized triazolopyridines and anilines followed by a second coupling with N-tosylhydrazones leading to the formation of Csp(3)-N and Csp(2)-Csp(2) bonds.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Lamaa, D; Lin, HP; Bzeih, T; Retailleau, P; Alami, M; Hamze, A or concate me.. COA of Formula: C12H9NO

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Yu, H; Zhao, QX; Wei, ZY; Wu, ZK; Li, Q; Han, S; Wei, YG in ROYAL SOC CHEMISTRY published article about C-H OXIDATION; AEROBIC OXIDATION; POLYOXOMETALATE; OXYGEN; ACTIVATION; REMOTE in [Yu, Han; Zhao, Qixin; Wei, Zheyu; Wu, Zhikang; Han, Sheng] Shanghai Inst Technol, Sch Chem & Environm Engn, Shanghai 201418, Peoples R China; [Yu, Han; Li, Qi; Wei, Yongge] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China; [Yu, Han; Wei, Yongge] Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China in 2019.0, Cited 48.0. Recommanded Product: Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

An efficient oxidation and functionalization of C-H bonds with an inorganic-ligand supported iron catalyst and hydrogen peroxide to prepare the corresponding ketones was achieved using the bromide ion as a promoter. Preliminary mechanistic investigations indicated that the bromide ion can bind to FeMo6 to form a supramolecular species (FeMo6 center dot 2Br), which can effectively catalyze the reaction.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Yu, H; Zhao, QX; Wei, ZY; Wu, ZK; Li, Q; Han, S; Wei, YG or concate me.. Recommanded Product: Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Category: pyridine-derivatives. I found the field of Pharmacology & Pharmacy very interesting. Saw the article Novel [1,2,3] triazolo[1,5-a]pyridine derivatives are trypanocidal by sterol biosynthesis pathway alteration published in 2019, Reprint Addresses Maya, JD (corresponding author), Univ Chile, Fac Med, Inst Ciencias Biomed ICBM, Clin & Mol Pharmacol Program, Independencia 1027, Santiago 1027, Chile.. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone.

Aim: To study a new series of [1,2,3] triazolo[1,5-alpha] pyridine derivatives as trypanocidal agents because current antichagasic pharmacologic therapy is only partially effective. Materials & methods: The effect of the series upon Trypanosoma cruzi epimastigotes and murine macrophages viability, cell cycle, cell death and on the metabolites of the sterol biosynthesis pathway was measured; also, docking in 14 alpha-demethylase was analyzed. Results: Compound 16 inhibits 14 alpha-demethylase producing an imbalance in the cholesterol/ergosterol synthesis pathway, as suggested by a metabolic control and theoretical docking analysis. Consequently, it prevented cell proliferation, stopping the cellular cycle at the G2/M phase, inducing cell death. Conclusion: Although the exact cell death mechanism remained elusive, this series can be used for the further rational design of novel antiparasitic molecules.

Category: pyridine-derivatives. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Lapier, M; Ballesteros-Garrido, R; Guzman-Rivera, D; Gonzalez-Herrera, F; Aguilera-Venegas, B; Moncada-Basualto, M; Ballesteros, R; Abarca, B; Pesce, B; Kemmerling, U; Olea-Azar, C; Maya, JD or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recently I am researching about ONE-POT SYNTHESIS; N-TOSYLHYDRAZONES; CATALYZED TRANSANNULATION; ASYMMETRIC HYDROGENATION; ETHYL DIAZOACETATE; C(SP(3))-H BONDS; DIAZO-COMPOUNDS; ARYLATION; DISCOVERY; NITRILES, Saw an article supported by the NSFCNational Natural Science Foundation of China (NSFC) [21302095]; Jiangsu Provincial NSF [BK20130924]; Nanjing Tech University. Application In Synthesis of Phenyl(pyridin-2-yl)methanone. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Dong, C; Wang, X; Pei, ZB; Sheno, RW. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

Pyridotriazoles are utilized as robust building blocks to access alpha-secondary and alpha-tertiary pyridines via the development of a simple yet practically useful metal-free denitrogenative C-C cross-coupling with boronic acids. The reaction shows a high level of functional tolerance, broad substrate scope, and facile scalability. The synthetic potential of the method is demonstrated by the strurctural modification of a bioactive molecule and concise synthesis of pheniramine analogs.

Application In Synthesis of Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Dong, C; Wang, X; Pei, ZB; Sheno, RW or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Enamullah, M; Hossain, MA; Bindu, MM; Islam, MK; Zaman, MA in [Enamullah, Mohammed; Hossain, Mohammad Anwar; Bindu, Mortuza Mamun; Islam, Mohammad Khairul; Zaman, Mohammad Al-Moktadir] Jahangirnagar Univ, Dept Chem, Dhaka, Bangladesh published Diastereoselection and induced chirality at-metal in distorted-tetrahedralbis[(RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamino-kappa N-2,N]-Delta/?-copper(PF6)(2) in 2020.0, Cited 41.0. Application In Synthesis of Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

The enantiopure Schiff bases (RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamine (R-1= H and OCH3) are synthesized from reaction between the 2-benzoyl-pyridine andchiral-amine (RorS)-1-(p-R-1-C6H4)ethylamine, respectively. These Schiff bases react with the copper(II) acetate to give distorted-tetrahedralbis[(RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamino-kappa N-2,N]-Delta/?-Cu(PF6)(2)in the presence of NH4PF6. A conformational change fromcis- totrans-isomer occurs in solution and thereby, the copper(II) coordinates to the solelytrans-form to provide the complexes. Cyclic voltammograms demonstrate two quasi-reversible one electron charge transfer processes for the Cu2+/Cu(+)and Cu+/Cu(0)couples in acetonitrile. ECD spectra reveal expected mirror-image relationships and indicate enantiopurity or enantiomeric excess of theRorS-ligands and their associated complexes in solution. Comparisons of experimental and simulated ECD spectra suggest induced chirality at-metal center, which diastereoselectively provides the Delta-Cu-Ror ?-Cu-Sdiastereomer as major product in solution. DFT/TDDFT optimized structures and excited state properties correspond well to the experimental results.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Enamullah, M; Hossain, MA; Bindu, MM; Islam, MK; Zaman, MA or concate me.. Application In Synthesis of Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem