Category: 91-02-1

Recently I am researching about GOLD-BASED DRUGS; CRYSTAL-STRUCTURE; ANTICANCER AGENTS; 2-SUBSTITUTED PYRIDINES; SOLUTION CHEMISTRY; CARBENE COMPLEXES; CYTOTOXICITY; REACTIVITY; DERIVATIVES; INHIBITION, Saw an article supported by the University of Kentucky; UK Igniting Research Collaboration (IRC). Recommanded Product: 91-02-1. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Gukathasan, S; Parkin, S; Awuah, SG. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

The synthesis of a novel class of cyclometalated gold(III) complexes supported by benzoylpyridine, benzylpyridine, and (1R,2R)-(+)-1,2-diaminocyclohexane (DACH) ligands, along with their crystal structures, is reported. These compounds provide a new scaffold to investigate biological properties of gold(III) complexes. The six complexes were prepared and characterized, following reactions of (C,N) cyclometalated gold(III) scaffolds, [Au(C boolean AND N)Cl-2] with DACH, which yielded a new series of cyclometaled gold(III), 3-5, of the type [Au(C boolean AND NH)(DACH)(2)](+) and the nitrogen substituted cyclometalated Au(III), 6-8, of the type [Au-(C boolean AND N)(DACH)](2+). Antiproliferative activity of these complexes in a panel of cancer cells showed promising results with IC50 in the micromolar range and selectivity over normal epithelial cells, MRCS. Whereas 8 shows minimal interaction with superhelical DNA except at high gold concentrations of 500 mu M, complex 5 does not show interaction even at 1000 mu M. The complexes display significant uptake in OVCAR8 cancer cells within 200-1200 pmol/million cells with the exception of complex 4. Differential cellular uptake was observed for the complexes; for example, while 3 and 8 display significant uptake, 4 showed minimal uptake. The compounds proved to be stable under physiological conditions and were minimally affected by either glutathione or sodium ascorbate. Cell cycle studies reveal a G1 arrest induced by representative complexes. The results reveal that enhanced Au(III) stabilization promoted by combined cyclometalated and DACH ligands may offer ligand tuning insights for novel anticancer drug design.

Recommanded Product: 91-02-1. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Gukathasan, S; Parkin, S; Awuah, SG or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Mn(III) active site in hydrotalcite efficiently catalyzes the oxidation of alkylarenes with molecular oxygen WOS:000604626700006 published article about LAYERED DOUBLE HYDROXIDES; LIQUID-PHASE OXIDATION; SELECTIVE OXIDATION; AEROBIC OXIDATION; AROMATIC KETONES; MEDIATED OXIDATION; MN; NI; ACETOPHENONE; ETHYLBENZENE in [Wang, Anwei; Zhou, WeiYou; Sun, Zhonghua; Zhang, Zhong; Zhang, Zhihui; He, MingYang; Chen, Qun] Changzhou Univ, Jiangsu Key Lab Adv Catalyt Mat & Technol, Changzhou 213164, Peoples R China in 2021, Cited 73. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Quality Control of Phenyl(pyridin-2-yl)methanone

Developing efficient heterogeneous catalytic systems based on easily available materials and molecular oxygen for the selective oxidation of alkylarenes is highly desirable. In the present research, NiMn hydrotalcite (Ni2Mn-LDH) has been found as an efficient catalyst in the oxidation of alkylarenes using molecular oxygen as the sole oxidant without any additive. Impressive catalytic performance, excellent stability and recyclability, broad applicable scope and practical potential for the catalytic system have been observed. Mn3+ species was proposed to be the efficient active site, and Ni2+ played an important role in stabilizing the Mn3+ species in the hydrotalcite structure. The kinetic study showed that the aerobic oxidation of diphenylmethane is a first-order reaction over Ni2Mn-LDH with the activation energy (E-a) and pre-exponential factor (A(0)) being 85.7 kJ mol(-1) and 1.8 x 109 min(-1), respectively. The Gibbs free energy (Delta G(not equal)) was determined to be -10.4 kJ mol(-1) K-1 for the oxidation based on Eyring-Polanyi equation, indicating the reaction is exergonic. The mechanism study indicated that the reaction proceeded through both radical and carbocation intermediates. The two species were then trapped by molecular oxygen and H2O or hydroxyl species, respectively, to yield the corresponding products. The present research might provide information for constructing highly efficient and stable active site for the catalytic aerobic oxidation based on available and economic material.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Wang, AW; Zhou, WY; Sun, ZH; Zhang, Z; Zhang, ZH; He, MY; Chen, Q or concate me.. Quality Control of Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Chirality-Economy Catalysis: Asymmetric Transfer Hydrogenation of Ketones by Ru-Catalysts of Minimal Stereogenicity WOS:000471212600085 published article about ENANTIOSELECTIVE TRANSFER HYDROGENATION; LIGAND BIFUNCTIONAL CATALYSIS; ACHIRAL BENZOPHENONE LIGAND; RUTHENIUM(II) COMPLEXES; AROMATIC KETONES; DIAMINE; REDUCTION; MECHANISM; ALCOHOLS; NETWORK in [Chen, Fumin; He, Dongxu; Chang, Xiaoyong; Xu, Chen; Xing, Xiangyou] Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518055, Peoples R China; [Chen, Fumin; He, Dongxu; Chang, Xiaoyong; Xu, Chen; Xing, Xiangyou] Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China; [Chen, Li; Wang, David Zhigang] Peking Univ, Shenzhen Grad Sch, Sch Chem Biol & Biotechnol, Shenzhen 518055, Peoples R China; [Chen, Li] Danzao Subbur Adm Social Insurance Fund Fushan Na, Foshan 528216, Peoples R China; [Wang, David Zhigang] Shenzhen UV ChemTech, Shenzhen 518057, Peoples R China in 2019.0, Cited 36.0. Product Details of 91-02-1. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

This manuscript describes the design and synthesis of Ru catalysts that feature only a single stereogenic element, yet this minimal chirality resource is demonstrated to be competent for effecting high levels of stereoinduction in the asymmetric transfer hydrogenation over a broad range of ketone substrates, including those that are not accommodated by known catalyst systems. The single stereogenic center of the (1-pyridine-2-yl)methanamine) is the only point-chirality in the catalysts, which simplifies this catalyst system relative to existing literature protocols.

Product Details of 91-02-1. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Chen, FM; He, DX; Chen, L; Chang, XY; Wang, DZ; Xu, C; Xing, XY or concate me.

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Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

In 2019.0 CHEMELECTROCHEM published article about C-H FUNCTIONALIZATION; CATALYZED TRANSANNULATION; EFFICIENT SYNTHESIS; COUPLING REACTIONS; PYRIDOTRIAZOLES; METAL; STRATEGIES; HYDRAZONES; OXIDATION; PYRIDINES in [Xu, Pin; Xu, Hai-Chao] Xiamen Univ, State Key Lab Phys Chem Solid Surfaces, Coll Chem & Chem Engn, Xiamen 361005, Fujian, Peoples R China in 2019.0, Cited 61.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Computed Properties of C12H9NO

The synthesis of [1,2,3]triazolo[1,5-a]pyridines through electrochemical dehydrogenative cyclization of hydrazones of 2-acylpyridines is presented. The reactions are carried out under mild conditions without oxidizing reagents or transition-metal catalysts.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Xu, P; Xu, HC or concate me.. Computed Properties of C12H9NO

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Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

SDS of cas: 91-02-1. In 2019.0 TRANSIT METAL CHEM published article about SUZUKI-MIYAURA REACTION; NITROGEN DOUBLE-BONDS; OXIDATIVE ADDITION; ARYL CHLORIDES; (NHC)PD(ALLYL)CL NHC; HETEROARYL HALIDES; CONVENIENT ACCESS; PYRIDINE HALIDES; PD(II) COMPLEXES; BORONIC ACIDS in [Boubakri, L.; Hamdi, N.] Univ Carthage, Higher Inst Environm Sci & Technol, Res Lab Environm Sci & Technol LR16ES09, Hammam Lif, Tunisia; [Al-Ayed, Abdullah S.; Hamdi, N.] Qassim Univ, Coll Arts & Sci, Dept Chem, Al Rass, Saudi Arabia; [Mansour, L.; Harrath, A. A.; Al-Tamimi, J.] King Saud Univ, Coll Sci, Dept Zool, POB 2455, Riyadh 11451, Saudi Arabia; [Ozdemir, I.; Yasar, S.] Inonu Univ, Fac Sci & Art, Dept Chem, Malatya, Turkey in 2019.0, Cited 86.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

The carbonylative Suzuki cross-coupling of 2-bromopyridine with various boronic acids to prepare unsymmetrical arylpyridine ketones has been carried out using palladium/N-heterocyclic carbene complexes as catalysts prepared in situ. The selectivity and the rate of these reactions are highly dependent on the conditions, i.e., nature of the palladium catalyst precursor, solvent, temperature and CO pressure. The main side-products arise from direct, non-carbonylative cross-coupling. Under the optimum conditions, arylpyridine ketones are recovered in high yields (60-88%). The antibacterial activities of the corresponding benzimidazole salts 2 were tested against Gram positive and negative bacteria using the agar dilution procedure, and their IC50 values have been determined.

SDS of cas: 91-02-1. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Boubakri, L; Al-Ayed, AS; Mansour, L; Harrath, AA; Al-Tamimi, J; Ozdemir, I; Yasar, S; Hamdi, N or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Recyclable Heterogeneous Copper(II)-Catalyzed Oxidative Cyclization of 2-Pyridine Ketone Hydrazones Towards [1,2,3]Triazolo[1,5-a]pyridines WOS:000498564900018 published article about N BOND-FORMATION; SP(3) C-H; CATALYZED DENITROGENATIVE TRANSANNULATION; CROSS-COUPLING REACTIONS; ONE-POT SYNTHESIS; EFFICIENT SYNTHESIS; COORDINATION-COMPOUNDS; MAGNETIC-PROPERTIES; CRYSTAL-STRUCTURE; MOLECULAR-OXYGEN in [Jiang, Gan; Lin, Yang; Zhao, Hong] Guangdong Pharmaceut Univ, Guangdong Cosmet Engn & Technol Res Ctr, Sch Chem & Chem Engn, Guangzhou 510006, Guangdong, Peoples R China; [Cai, Mingzhong] Jiangxi Normal Univ, Coll Chem & Chem Engn, Nanchang 330022, Jiangxi, Peoples R China in 2019.0, Cited 99.0. Computed Properties of C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

The heterogeneous copper(II)-catalyzed oxidative cyclization of 2-pyridine ketone hydrazones was achieved in ethyl acetate at room temperature in the presence of an MCM-41-anchored bidentate 2-aminoethylamino copper(II) catalyst [MCM-41-2N-Cu(OAc) (2) ], in the presence of air as the oxidant, yielding a wide variety of [1,2,3]triazolo[1,5- a ]pyridines in mostly good to high yields. The present method was also applied to the direct one-pot synthesis of [1,2,3]triazolo[1,5- a ]pyridines from 2-acylpyridine derivatives and hydrazine monohydrate. Importantly, this supported copper(II) catalyst could be conveniently obtained via a simple procedure from easily available and inexpensive reagents, recovered by filtration of the reaction mixture, and reused at least seven times without a significant loss of catalytic activity.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Jiang, G; Lin, Y; Cai, MZ; Zhao, H or concate me.. Computed Properties of C12H9NO

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recently I am researching about TURN-ON; AQUEOUS-MEDIUM; ALUMINUM; SENSOR; DIARYLETHENE; WATER; IONS, Saw an article supported by the CSIR, New Delhi, IndiaCouncil of Scientific & Industrial Research (CSIR) – India [01(2992)/19/EMR-II]; Dr. D. S. Kothari fellowship (UGC); UGC-IndiaUniversity Grants Commission, India. Name: Phenyl(pyridin-2-yl)methanone. Published in ELSEVIER SCIENCE SA in LAUSANNE ,Authors: Gharami, S; Aich, K; Ghosh, P; Patra, L; Murmu, N; Mondal, TK. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

A new coumarin based fluorescent switch (HCBP) has been fabricated which displays high selective sensing towards Al3+ among other metal cations at physiological pH. On gradual addition of Al3+ specifically, HCBP shows a brilliant turn-on emission enhancement of about similar to 13-fold with about 50 nm red shift at 481 nm in MeOH/H2O (1/1, v/v) solution. The fluorescent switch is proven to be a reversible probe by addition of EDTA gradually into the HCBP-Al3+ solution. Detection limit as well as Binding constant values have been calculated and found to be in the order of 10(-9) M and 10(3) M-1 respectively. DFT and TDDFT studies are conducted with the probe to establish a similarity between theoretical and experimental outcomes. We can also use this new fluorescent switch as a biomarker kit as it has shown a brilliant potential in the application of live cell imaging using gastric cancer cell (AGS cell).

Name: Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Gharami, S; Aich, K; Ghosh, P; Patra, L; Murmu, N; Mondal, TK or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Solvent-free microwave-assisted synthesis of imidazo[1,5-a]pyridine and -quinoline derivatives WOS:000481164400001 published article about RATIOMETRIC FLUORESCENT-PROBE; COMPLEXES; EFFICIENT; LIGHT; TRANSANNULATION; ALDEHYDES; EMISSION; LIGANDS; IMIDAZO; SHIFT in [Herr, Jasmin Martha; Roessiger, Carina; Goettlich, Richard] Justus Liebig Univ Giessen, Inst Organ Chem, Heinrich Buff Ring 17, D-35392 Giessen, Germany; [Herr, Jasmin Martha; Roessiger, Carina; Albrecht, Georg; Goettlich, Richard] Justus Liebig Univ Giessen, Ctr Mat Res LaMa, Giessen, Germany; [Albrecht, Georg] Justus Liebig Univ Giessen, Inst Appl Phys, Giessen, Germany; [Yanagi, Hisao] NAIST, Dept Mat Sci, Nara, Japan in 2019.0, Cited 39.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Safety of Phenyl(pyridin-2-yl)methanone

A quick and highly efficient microwave-assisted preparation of imidazopyridines and -quinolines is described, starting from the corresponding ketones and amines. The method requires no solvent and uses activated MnO2 as an oxidant. A mechanism for the cyclization is proposed and discussed.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Herr, JM; Rossiger, C; Albrecht, G; Yanagi, H; Gottlich, R or concate me.. Safety of Phenyl(pyridin-2-yl)methanone

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Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Application In Synthesis of Phenyl(pyridin-2-yl)methanone. Singh, YP; Patel, SK in [Singh, Yogendra Pratap; Patel, Satish Kumar] APS Univ, Dept Chem, Rewa 486003, MP, India published Molecular structures, spectral, electrochemical, DFT and antioxidant activities of copper(II) complexes with NNO donor Schiff base ligand in 2021.0, Cited 72.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

The synthesis and solid state structural, spectral and electrochemical solution characterization of [Cu(L)(acpy)]ClO4 1 and [Cu(L)(NO3)]( )2 [where L = N'[(E)-phenyl(pyridin-2-yl)methylideneithiophene-2-carbohydrazide and acpy = 2,6-Diacetylpyridine] have been done by elemental analysis, UV-vis, FTIR, electrochemical techniques (CV and DPV) and electron paramagnetic resonance (epr) spectroscopy. The single crystal structures were solved by the X-ray diffraction technique. In complex 1, copper ion is in a distorted octahedral environment. The geometry of copper(II) in complex 2 is distorted square pyramidal (tau = 0.201). The mono deprotonated, HL ligand act as a tridentate to a copper(II) ion. On the basis of density functional theory (DFT) calculation, the electronic excitations involve transitions mainly from metal ligand bonding mostly the alpha-LUMO within the dominant Cu d(xy) character and to alpha-LUMO+1. Epr spectra for polycrystalline samples showed the copper(II) hyperfine features as well as half-field signal which are appropriate for Delta M-s = +/- 2 of dimers. Presence of half-field signal in 1 is due to solid-solid interaction (intra-molecular) where as in 2 the nature of interaction is intra-molecular. The antioxidant superoxide measurements show that the both complexes 1 and 2 behave as superoxide mimic in alkaline nitro blue tetrazolium chloride assay. (C) 2020 Elsevier B.V. All rights reserved.

Application In Synthesis of Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Singh, YP; Patel, SK or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Synthesis of a crystallochromic indolizine dye by a base- and catalyst-free photochemical route WOS:000485913000014 published article about CONFORMATIONAL POLYMORPHISM; PHOTOPHYSICAL PROPERTIES; EFFICIENT SYNTHESIS; OPTICAL-PROPERTIES; CASCADE APPROACH; COLOR; CHROMOPHORES; HETEROCYCLES in [Dohmen, Christoph; Ihmels, Heiko; Kreienmeier, Rouven] Univ Siegen, Dept Chem Biol Organ Chem 2, Adolf Reichwein Str 2, D-57068 Siegen, Germany; [Patrick, Brian O.] Univ British Columbia, Dept Chem, Struct Chem Facil, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada in 2019.0, Cited 64.0. Computed Properties of C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Indolizine derivatives are obtained by irradiation of 2-benzoyl-N-benzylpyridinium derivatives and dimethyl acetylene dicarboxylate, thus providing a competitive and complementary base- and catalyst-free synthesis. With this method, the first example of a crystallochromic indolizine is presented, whose color in the solid state depends on the out-of-plane torsion of the benzoyl substituent.

Computed Properties of C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Dohmen, C; Ihmels, H; Kreienmeier, R; Patrick, BO or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem