Category: 91-02-1

I found the field of Chemistry very interesting. Saw the article Diastereoselection and induced chirality at-metal in distorted-tetrahedralbis[(RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamino-kappa N-2,N]-Delta/?-copper(PF6)(2) published in 2020.0. COA of Formula: C12H9NO, Reprint Addresses Enamullah, M (corresponding author), Jahangirnagar Univ, Dept Chem, Dhaka, Bangladesh.. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

The enantiopure Schiff bases (RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamine (R-1= H and OCH3) are synthesized from reaction between the 2-benzoyl-pyridine andchiral-amine (RorS)-1-(p-R-1-C6H4)ethylamine, respectively. These Schiff bases react with the copper(II) acetate to give distorted-tetrahedralbis[(RorS)-1-(p-R-1-C6H4)-N-(phenyl(pyridin-2-yl)methylene)ethanamino-kappa N-2,N]-Delta/?-Cu(PF6)(2)in the presence of NH4PF6. A conformational change fromcis- totrans-isomer occurs in solution and thereby, the copper(II) coordinates to the solelytrans-form to provide the complexes. Cyclic voltammograms demonstrate two quasi-reversible one electron charge transfer processes for the Cu2+/Cu(+)and Cu+/Cu(0)couples in acetonitrile. ECD spectra reveal expected mirror-image relationships and indicate enantiopurity or enantiomeric excess of theRorS-ligands and their associated complexes in solution. Comparisons of experimental and simulated ECD spectra suggest induced chirality at-metal center, which diastereoselectively provides the Delta-Cu-Ror ?-Cu-Sdiastereomer as major product in solution. DFT/TDDFT optimized structures and excited state properties correspond well to the experimental results.

COA of Formula: C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Enamullah, M; Hossain, MA; Bindu, MM; Islam, MK; Zaman, MA or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recommanded Product: Phenyl(pyridin-2-yl)methanone. Recently I am researching about CATALYZED DENITROGENATIVE TRANSANNULATION; METAL-ORGANIC FRAMEWORK; ONE-POT SYNTHESIS; H BONDS; COUPLING REACTION; BENZYLIC HALIDES; GENERAL-METHOD; ARYL BROMIDES; ARYLATION; FUNCTIONALIZATION, Saw an article supported by the IIT Madras (IRDA project) [CHY/17-18/RFIR/GSEK]; UGC, New DelhiUniversity Grants Commission, India; IIT Madras. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Chandrasekar, S; Sangeetha, S; Sekar, G. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

A simple, effortless, and efficacious protocol for the synthesis of highly fluorescing imidazo[1,5-a]pyridines via copper catalyzed inter-/intramolecular C-N bond formation between readily available pyridyl alcohols with either benzyl amines or amino acids has been developed. This domino reaction is involved with alcohol oxidation/condensation/oxidative amination sequence to synthesize imidazo[1,5-a]pyridines in good to excellent yields. The fluorescence studies of these compounds indicated a bathochromic shift for the electron donating substituents, whereas a hypsochromic shift for the electron withdrawing substituents. Synthetic modification of the groups attached to the heterocyclic core showed a profound impact on the emission properties when subjected to pH and solvent polarity change.

Recommanded Product: Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Chandrasekar, S; Sangeetha, S; Sekar, G or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Development of Bronsted Base-Photocatalyst Hybrid Systems for Highly Efficient C-C Bond Formation Reactions of Malonates with Styrenes WOS:000574920200025 published article about CATALYTIC RADICAL-ADDITION; PHOTOCHEMICAL MONOALKYLATION; ALKENES; SUBSTITUTION; REACTIVITY in [Bas, Sebastian; Yamashita, Yasuhiro; Kobayashi, Shu] Univ Tokyo, Sch Sci, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan in 2020, Cited 31. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1. Application In Synthesis of Phenyl(pyridin-2-yl)methanone

Bronsted base-photocatalyst hybrid systems have been developed for reactions of malonates with styrene derivatives. The concept of this process lies in the photo-oxidation of catalytic amounts of the enolate to form reactive radicals that react with alkene double bonds under mild reaction conditions. This is an example of visible-light-activated C-C bond formation reactions of malonates with alkenes to realize high atom economy under very mild reaction conditions without using any transition-metal catalysts.

Application In Synthesis of Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Bas, S; Yamashita, Y; Kobayashi, S or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Dasgupta, S; Karim, S; Banerjee, S; Saha, M; Saha, KD; Das, D in ROYAL SOC CHEMISTRY published article about NI-II COMPLEXES; MOLECULAR-STRUCTURE; HYDROLYSIS; MECHANISM; LIGANDS; ESTERS; DRUGS; COBALT(III); DERIVATIVES; KINETICS in [Dasgupta, Sanchari; Karim, Suhana; Das, Debasis] Univ Calcutta, Dept Chem, 92 APC Rd, Kolkata 700009, India; [Banerjee, Saswati; Saha, Moumita; Saha, Krishna Das] CSIR Indian Inst Chem Biol, Canc Biol & Inflammatory Disorder Div, 4 Raja SC Mullick Rd, Kolkata 700032, India in 2020.0, Cited 48.0. Quality Control of Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Three asymmetric tridentate acyl hydrazone Schiff base ligands namely L1, L2 and L3 were prepared via condensation of 4-methoxybenzohydrazide with picolinaldehyde, 1-(pyridin-2-yl)ethanone and phenyl(pyridin-2-yl)methanone respectively. Three bio-relevant mononuclear zinc(ii) complexes [Zn(L1)Cl-2]2H(2)O (1), [Zn(L2)Cl-2] (2) and [Zn(L3)Cl-2] (3) were synthesized by treatment of zinc(ii) chloride with the corresponding Schiff base ligands and characterised by the usual physicochemical techniques. The solid state structures of complexes 1 and 3 were evaluated by single crystal X-ray analysis. All complexes were able to hydrolyse the P-O bond of the phosphate monoester in 90% (v/v) DMSO-water medium using 4-nitrophenylphosphate (4-NPP) as the model substrate and the trend in their activity is 1 approximate to 2 > 3. On considering the highly efficient hydrolysis properties, complexes 1-3 were tested as potential therapeutic agents for cancer using HCT116 (human colorectal carcinoma), HepG2 (human hepatocellular carcinoma) and A549 (human non-small lung carcinoma) cells. Complex 2 showed the highest IC50 values for anti-cancer activity towards all three cell lines among the three complexes and complex 3 showed the least activity as observed in the phosphatase activity study. The internucleosomal degradation of DNA during apoptosis can be detected by cell death detection ELISA. DNA fragmentation that leads to cell death was examined and when induced by complex 2 in HepG2 cells a significant level of DNA fragmentation was observed at regular intervals of time.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Dasgupta, S; Karim, S; Banerjee, S; Saha, M; Saha, KD; Das, D or concate me.. Quality Control of Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Transfer hydrogenation of ketones catalyzed by 2,6-bis(triazinyl) pyridine ruthenium complexes: The influence of alkyl arms WOS:000484876900003 published article about ASYMMETRIC TRANSFER HYDROGENATION; LIGAND; EXTRACTION; SEPARATION; BEARING; ENANTIOSELECTIVITY; PALLADIUM; ACTINIDES in [Wang, Liandi; Liu, Tingting] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Liaoning, Peoples R China; [Liu, Tingting] Henan Acad Sci, Inst Chem, Zhengzhou 450002, Henan, Peoples R China in 2019.0, Cited 42.0. COA of Formula: C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

The transfer hydrogenation of ketones catalyzed by transition metal complexes has attracted much attention. A series of ruthenium(11) complexes bearing 2,6-bis(5,6-dialkyl-1,2,4-triazin-3-yl)pyridine ligands (R-BTPs) were synthesized and characterized by NMR analysis and X-ray diffraction. These ruthenium (II) complexes were applied in the transfer hydrogenation of ketones. Their different catalytic activity were attributed to the alkyl arms on the 2,6-bis(5,6-dialkyl-1,2,4-triazin-3-yl)pyridine. As the length of the alkyl arms rising, the catalytic activities of the complex catalysts decreased. By means of 0.4 mol % catalyst RuCl2(PPh3)(3-methylbutyl-BTP) in refluxing 2-propanol, a variety of ketones were reduced to their corresponding alcohols with >95% conversion over a period of 3 h. (C) 2019 Elsevier Science. All rights reserved. (C) 2019 Elsevier Ltd. All rights reserved.

COA of Formula: C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Wang, LD; Liu, TT or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recently I am researching about TRANSITION-METAL-COMPLEXES; CATIONIC IRIDIUM COMPLEXES; ELECTROLUMINESCENT DEVICES; PALLADIUM(II) COMPLEXES; HIGH-BRIGHTNESS; SOLID-STATE; WHITE-LIGHT; LOW-VOLTAGE; CYCLOMETALATED PALLADIUM(II); QUANTUM EFFICIENCY, Saw an article supported by the NSERCNatural Sciences and Engineering Research Council of Canada (NSERC) [DG 2018-04255]; Iran National Science FoundationIran National Science Foundation (INSF) [97017697]. Safety of Phenyl(pyridin-2-yl)methanone. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Emami, M; Shahroosvand, H; Bikas, R; Lis, T; Daneluik, C; Pilkington, M. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

For the first time, square planar Pd(II) complexes of hydrazone ligands have been investigated as the emissive components of light-emitting electrochemical cells (LECs). The neutral transition metal complex, [Pd(L-1)(2)]center dot 2CH(3)OH (1), (HL1 = (E)-N’-(phenyl(pyridin-2-yl) methylene)isonicotinhydrazide), was prepared and structurally characterized. Complex 1 displays quasireversible redox properties and is emissive at room temperature in solution with a lambda(max) of 590 nm. As a result, it was subsequently employed as the emissive material of a single-layer LEC with configuration FTO/1/Ga/In, where studies reveal that it has a yellow color with CIE(x, y) = (0.33, 0.55), a luminance of 134 cd cm(-2), and a turn-on voltage of 3.5 V. Protonation of the pendant pyridine nitrogen atoms of L-1 afforded a second ionic complex [Pd((LH)-H-1)(2)](ClO4)(2) (2) which is also emissive at room temperature with a lambda(max) of 611 nm, resulting in an orange LEC with CIE(x, y) = (0.43, 0.53). The presence of mobile anions and cations in the second inorganic transition metal complex resulted in more efficient charge injection and transport which significantly improved the luminance and turn-on voltage of the device to 188.6 cd cm(-2) and 3 V, respectively. This study establishes Pd(II) hydrazone complexes as a new class of materials whose emissive properties can be chemically tuned and provides proof-of-concept for their use in LECs, opening up exciting new avenues for potential applications in the field of solid state lighting.

Safety of Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Emami, M; Shahroosvand, H; Bikas, R; Lis, T; Daneluik, C; Pilkington, M or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recommanded Product: 91-02-1. In 2020.0 EUR J ORG CHEM published article about HORIUTI-POLANYI MECHANISM; STABILIZED PALLADIUM NANOPARTICLES; COPD BIOMARKER DESMOSINE; HETEROGENEOUS CATALYSIS; CARBOXYLIC-ACIDS; IONIC LIQUIDS; AMINES; WATER; HYDRODEHALOGENATION; TRANSFORMATION in [Tanaka, Nao; Usuki, Toyonobu] Sophia Univ, Dept Mat & Life Sci, Fac Sci & Technol, Chiyoda Ku, 7-1 Kioicho, Tokyo 1028554, Japan in 2020.0, Cited 79.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

Hydrogenation of over a dozen aromatic compounds, including both heteroarenes and arenes, over palladium on carbon (Pd/C, 1-100 mol%) with H-2-balloon pressure at room temperature is reported. Analyses using pyridine as a model substrate revealed that acetic acid was the best solvent, as using only 1 mol% Pd/C provided piperidine quantitatively. Substrate scope analysis and density functional theory calculations indicated that reaction rates are highly dependent on frontier molecular orbital characteristics and the steric bulkiness of substituents. Moreover, the established method was used for the concise synthesis of the anti-Alzheimer drug donepezil (Aricept (R)).

Recommanded Product: 91-02-1. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Tanaka, N; Usuki, T or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

I found the field of Chemistry very interesting. Saw the article Electrochemical benzylic oxidation of C-H bonds published in 2019.0. Formula: C12H9NO, Reprint Addresses Liu, W (corresponding author), Miami Univ, Dept Chem & Biochem, Oxford, OH 45056 USA.. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

Oxidized products have become increasingly valuable as building blocks for a wide variety of different processes and fine chemistry, especially in the benzylic position. We report herein a sustainable protocol for this transformation through C-H functionalization and is performed using electrochemistry as the main power source and tert-butyl hydroperoxide as the radical source for the C-H abstraction. The temperature conditions reported here do not increase above 50 degrees C and use an aqueous-based medium. A broad substrate scope is explored, along with bioactive molecules, to give comparable and increased product yields when compared to prior reported literature without the use of electrochemistry.

Formula: C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Marko, JA; Durgham, A; Bretz, SL; Liu, W or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

An article Chirality-Economy Catalysis: Asymmetric Transfer Hydrogenation of Ketones by Ru-Catalysts of Minimal Stereogenicity WOS:000471212600085 published article about ENANTIOSELECTIVE TRANSFER HYDROGENATION; LIGAND BIFUNCTIONAL CATALYSIS; ACHIRAL BENZOPHENONE LIGAND; RUTHENIUM(II) COMPLEXES; AROMATIC KETONES; DIAMINE; REDUCTION; MECHANISM; ALCOHOLS; NETWORK in [Chen, Fumin; He, Dongxu; Chang, Xiaoyong; Xu, Chen; Xing, Xiangyou] Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518055, Peoples R China; [Chen, Fumin; He, Dongxu; Chang, Xiaoyong; Xu, Chen; Xing, Xiangyou] Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China; [Chen, Li; Wang, David Zhigang] Peking Univ, Shenzhen Grad Sch, Sch Chem Biol & Biotechnol, Shenzhen 518055, Peoples R China; [Chen, Li] Danzao Subbur Adm Social Insurance Fund Fushan Na, Foshan 528216, Peoples R China; [Wang, David Zhigang] Shenzhen UV ChemTech, Shenzhen 518057, Peoples R China in 2019.0, Cited 36.0. Safety of Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

This manuscript describes the design and synthesis of Ru catalysts that feature only a single stereogenic element, yet this minimal chirality resource is demonstrated to be competent for effecting high levels of stereoinduction in the asymmetric transfer hydrogenation over a broad range of ketone substrates, including those that are not accommodated by known catalyst systems. The single stereogenic center of the (1-pyridine-2-yl)methanamine) is the only point-chirality in the catalysts, which simplifies this catalyst system relative to existing literature protocols.

Safety of Phenyl(pyridin-2-yl)methanone. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Chen, FM; He, DX; Chen, L; Chang, XY; Wang, DZ; Xu, C; Xing, XY or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recently I am researching about ASYMMETRIC HYDROGENATION; NITRIC-ACID; CHEMISTRY; SYSTEM; GENERATION; CONVERSION; NITRATION; ARYL, Saw an article supported by the Shanghai Post-doctoral Excellence Program, Shanghai Sailing Program [20YF1410400]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21572056]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities; 111 projectMinistry of Education, China – 111 Project [B07023]; Open Project of State Key Laboratory of Chemical Engineering [SKL-ChE-17C01]. HPLC of Formula: C12H9NO. Published in SPRINGER in NEW YORK ,Authors: Sun, ML; Li, JC; Liang, CM; Shan, C; Shen, XY; Cheng, RH; Ma, YY; Ye, JX. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone

2-Pyridyl ketones widely appear in bioactive molecules, natural products, and are employed as precursors of chiral 2-pyridine alky/aryl alcohols or 2-aminoalkyl pyridine ligands for asymmetric catalysis. Herein, a practical method for the rapid synthesis of 2-pyridyl ketone library in continuous flow is reported, in which the 2-lithiopyridine formed by Br/Li exchange reacts with commercially available esters to obtain 2-pyridyl ketones in a good yield at short reaction time. This protocol functions broadly on a variety of esters and has been applied to the synthesis of TGF-beta type 1 receptor inhibitor LY580276 intermediate in an environmentally friendly method. It is rapid, reliable, and cost-efficient to afford diverse kinds of 2-pyridyl ketones in the compound library.

HPLC of Formula: C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Sun, ML; Li, JC; Liang, CM; Shan, C; Shen, XY; Cheng, RH; Ma, YY; Ye, JX or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem