Category: 91-02-1

Recently I am researching about LARGE STOKES SHIFT; FLUORESCENT-PROBE; SELECTIVE DETECTION; CYSTEINE; GLUTATHIONE; SENSOR; HOMOCYSTEINE; ROLES, Saw an article supported by the Natural Science Foundation of Heilongjiang Province of ChinaNatural Science Foundation of Heilongjiang Province [LH2019B033]. Published in MDPI in BASEL ,Authors: Chen, S; Hou, P; Sun, JW; Wang, HJ; Liu, L. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone. Name: Phenyl(pyridin-2-yl)methanone

A new cyan fluorescent probe, MIPY-DNBS, using an imidazo[1,5-alpha]pyridine derivative as the fluorophore and 2,4-dinitrobenzensufonate as the recognition site for the selective detection of thiols (Cys, GSH, and Hcy), was designed and synthesized. Probe MIPY-DNBS exhibited a 172 nm Stokes shift, a fast response time (400 s), low cytotoxicity, low detection limits (12.7 nM for Cys), and excellent selectively in the detection of thiols. In addition, MIPY-DNBS was successfully applied to imaging thiols in living MCF-7 cells and zebrafish.

Name: Phenyl(pyridin-2-yl)methanone. Welcome to talk about 91-02-1, If you have any questions, you can contact Chen, S; Hou, P; Sun, JW; Wang, HJ; Liu, L or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recommanded Product: 91-02-1. In 2019.0 ADV SYNTH CATAL published article about C-H HYDROXYLATION; C(SP(2))-H BOND HYDROXYLATION; CARBOXYLIC-ACIDS; OXYGENATION; RUTHENIUM; FUNCTIONALIZATION; ACYLATION; PHENOL; DERIVATIVES; HETEROCYCLES in [Saha, Rajib; Perveen, Naziya; Nihesh, Naorem; Sekar, Govindasamy] Indian Inst Technol Madras, Dept Chem, Chennai 600036, India in 2019.0, Cited 61.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

An efficient, reusable and stable binaphthyl stabilized Pd-nanoparticles (Pd-BNP) catalyzed the direct ortho-C-H hydroxylation of acetophenone oxime ethers under neutral and phosphine ligand-free condition has been developed. A readily available, economic, safe and greener oxidant oxone has been used in this direct ortho-hydroxylation. The scope of the reaction has been studied with various acetophenone oxime ethers including electron rich to electron deficient system and the reaction afforded only mono hydroxylated products in a highly regioselective manner. Several control experiment results confirmed that the oxone is the hydroxyl source. The Pd-BNP catalyst has been reused up to five times. The heterogeneous test confirmed that the reaction is catalyzed by the heterogeneous Pd-BNP catalyst.

Recommanded Product: 91-02-1. Welcome to talk about 91-02-1, If you have any questions, you can contact Saha, R; Perveen, N; Nihesh, N; Sekar, G or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Kim, JH; Ofori, S; Parkin, S; Vekaria, H; Sullivan, PG; Awuah, SG in ROYAL SOC CHEMISTRY published article about in [Kim, Jong Hyun; Ofori, Samuel; Parkin, Sean; Awuah, Samuel G.] Univ Kentucky, Dept Chem, Lexington, KY 40506 USA; [Awuah, Samuel G.] Univ Kentucky, Coll Pharm, Ctr Pharmaceut Res & Innovat, Lexington, KY 40536 USA; [Awuah, Samuel G.] Univ Kentucky, Coll Pharm, Dept Pharmaceut Sci, Lexington, KY 40536 USA; [Vekaria, Hemendra; Sullivan, Patrick G.] Univ Kentucky, Spinal Cord & Brain Injury Res Ctr, Lexington, KY USA; [Sullivan, Patrick G.] Univ Kentucky, Dept Neurosci, Lexington, KY USA; [Sullivan, Patrick G.] Lexington Vet Affairs Healthcare Syst, Lexington, KY USA in 2021.0, Cited 75.0. Name: Phenyl(pyridin-2-yl)methanone. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Expanding the chemical diversity of metal complexes provides a robust platform to generate functional bioactive reagents. To access an excellent repository of metal-based compounds for probe/drug discovery, we capitalized on the rich chemistry of gold to create organometallic gold(III) compounds by ligand tuning. We obtained novel organogold(III) compounds bearing a 1,2-bis(diphenylphosphino)benzene ligand, providing structural diversity with optimal physiological stability. Biological evaluation of the lead compound AuPhos-89 demonstrates mitochondrial complex I-mediated alteration of the mitochondrial electron transport chain (ETC) to drive respiration and diminish cellular energy in the form of adenosine triphosphate (ATP). Mechanism-of-action efforts, RNA-Seq, quantitative proteomics, and NCI-60 screening reveal a highly potent anticancer agent that modulates mitochondrial ETC. AuPhos-89 inhibits the tumor growth of metastatic triple negative breast cancer and represents a new strategy to study the modulation of mitochondrial respiration for the treatment of aggressive cancer and other disease states where mitochondria play a pivotal role in the pathobiology.

Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.. Name: Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Singh, PR; Maji, A; Singh, O; Singh, UP; Ghosh, K in [Singh, Prasoon Raj; Maji, Ankur; Singh, Ovender; Singh, Udai P.; Ghosh, Kaushik] IIT Roorkee, Dept Chem, Roorkee 247667, Uttarakhand, India published Transfer hydrogenation via generation of hydride intermediate and base-free alcohol oxidation activity studies on designed ruthenium complexes derived from NNN pincer type ligands in 2020.0, Cited 59.0. COA of Formula: C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

Ruthenium complexes(1-3) have been synthesized using pincer-type ligands L-1 = (E)-2-((2-phenyl-2-(pyridin-2-yl)hydrazono)methyl)pyridine, L-2 = (E)-2-(1-phenyl-2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)pyridine, L-3 = (E)-2-(phenyl(2-phenyl-2-(pyridin-2-yl)hydrazono) methyl)pyridine. The molecular structures of all the complexes 1, 2 and 3 were determined by using single crystal X-ray diffraction. These complexes showed excellent catalytic activities such as transfer hydrogenation and alcohol oxidation. Theoretical calculations have been performed to understand the electronic properties of all the complexes using B3LYP as a function and LANL2DZ as a basis set.

Welcome to talk about 91-02-1, If you have any questions, you can contact Singh, PR; Maji, A; Singh, O; Singh, UP; Ghosh, K or send Email.. COA of Formula: C12H9NO

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Product Details of 91-02-1. In 2019 FUTURE MED CHEM published article about CELL-PROLIFERATION; STRUCTURAL-BASIS; DRUG CANDIDATES; CHOLESTEROL; 14-ALPHA-DEMETHYLASE; INHIBITION; INSIGHTS; BINDING; CYP51; CHAIN in [Lapier, Michel; Guzman-Rivera, Daniela; Gonzalez-Herrera, Fabiola; Pesce, Barbara; Maya, Juan D.] Univ Chile, Fac Med, Inst Ciencias Biomed ICBM, Clin & Mol Pharmacol Program, Independencia 1027, Santiago 1027, Chile; [Ballesteros-Garrido, Rafael; Ballesteros, Rafael; Abarca, Belen] Univ Valencia, Fac Pharm, Dept Organ Chem, Avda Vicent Andres Estelles S-N, E-46100 Valencia, Spain; [Aguilera-Venegas, Benjamin; Moncada-Basualto, Mauricio; Olea-Azar, Claudio] Univ Chile, Fac Chem & Pharmaceut Sci, Free Rad & Antioxidants Lab, Inorgan & Analyt Dept, Santos Dumt 964, Santiago, Chile; [Moncada-Basualto, Mauricio] Univ Santiago Chile, Fac Chem & Biol, Dept Environm Sci, Santiago, Chile; [Kemmerling, Ulrike] Univ Chile, Fac Med, Inst Ciencias Biomed ICBM, Anat & Dev Biol Program, Independencia 1027, Santiago, Chile in 2019, Cited 38. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

Aim: To study a new series of [1,2,3] triazolo[1,5-alpha] pyridine derivatives as trypanocidal agents because current antichagasic pharmacologic therapy is only partially effective. Materials & methods: The effect of the series upon Trypanosoma cruzi epimastigotes and murine macrophages viability, cell cycle, cell death and on the metabolites of the sterol biosynthesis pathway was measured; also, docking in 14 alpha-demethylase was analyzed. Results: Compound 16 inhibits 14 alpha-demethylase producing an imbalance in the cholesterol/ergosterol synthesis pathway, as suggested by a metabolic control and theoretical docking analysis. Consequently, it prevented cell proliferation, stopping the cellular cycle at the G2/M phase, inducing cell death. Conclusion: Although the exact cell death mechanism remained elusive, this series can be used for the further rational design of novel antiparasitic molecules.

About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Lapier, M; Ballesteros-Garrido, R; Guzman-Rivera, D; Gonzalez-Herrera, F; Aguilera-Venegas, B; Moncada-Basualto, M; Ballesteros, R; Abarca, B; Pesce, B; Kemmerling, U; Olea-Azar, C; Maya, JD or concate me.. Product Details of 91-02-1

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Recently I am researching about OLD YELLOW ENZYME; COMBINING PHOTOCATALYSIS; BIOCATALYTIC REDUCTION; RADICALS; BOND; DISSOCIATION; REDOX; HETEROCYCLES; BIOREDUCTION; COMPLEXES, Saw an article supported by the NSFNational Science Foundation (NSF) [1846861]; Searle Scholar Program; Sloan Scholar Program; Princeton UniversityPrinceton University; Australian GovernmentAustralian GovernmentCGIAR; DOE Office of ScienceUnited States Department of Energy (DOE) [DE-SC0012704]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Nakano, Y; Black, MJ; Meichan, AJ; Sandoval, BA; Chung, MM; Biegasiewicz, KF; Zhu, TY; Hyster, TK. The CAS is 91-02-1. Through research, I have a further understanding and discovery of Phenyl(pyridin-2-yl)methanone. COA of Formula: C12H9NO

Flavin-dependent ‘ene’-reductases (EREDs) are highly selective catalysts for the asymmetric reduction of activated alkenes. This function is, however, limited to enones, enoates, and nitroalkenes using the native hydride transfer mechanism. Here we demonstrate that EREDs can reduce vinyl pyridines when irradiated with visible light in the presence of a photoredox catalyst. Experimental evidence suggests the reaction proceeds via a radical mechanism where the vinyl pyridine is reduced to the corresponding neutral benzylic radical in solution. DFT calculations reveal this radical to be dynamically stable, suggesting it is sufficiently long-lived to diffuse into the enzyme active site for stereoselective hydrogen atom transfer. This reduction mechanism is distinct from the native one, highlighting the opportunity to expand the synthetic capabilities of existing enzyme platforms by exploiting new mechanistic models.

COA of Formula: C12H9NO. Bye, fridends, I hope you can learn more about C12H9NO, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Saha, R; Perveen, N; Nihesh, N; Sekar, G in WILEY-V C H VERLAG GMBH published article about C-H HYDROXYLATION; C(SP(2))-H BOND HYDROXYLATION; CARBOXYLIC-ACIDS; OXYGENATION; RUTHENIUM; FUNCTIONALIZATION; ACYLATION; PHENOL; DERIVATIVES; HETEROCYCLES in [Saha, Rajib; Perveen, Naziya; Nihesh, Naorem; Sekar, Govindasamy] Indian Inst Technol Madras, Dept Chem, Chennai 600036, India in 2019.0, Cited 61.0. HPLC of Formula: C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

An efficient, reusable and stable binaphthyl stabilized Pd-nanoparticles (Pd-BNP) catalyzed the direct ortho-C-H hydroxylation of acetophenone oxime ethers under neutral and phosphine ligand-free condition has been developed. A readily available, economic, safe and greener oxidant oxone has been used in this direct ortho-hydroxylation. The scope of the reaction has been studied with various acetophenone oxime ethers including electron rich to electron deficient system and the reaction afforded only mono hydroxylated products in a highly regioselective manner. Several control experiment results confirmed that the oxone is the hydroxyl source. The Pd-BNP catalyst has been reused up to five times. The heterogeneous test confirmed that the reaction is catalyzed by the heterogeneous Pd-BNP catalyst.

Welcome to talk about 91-02-1, If you have any questions, you can contact Saha, R; Perveen, N; Nihesh, N; Sekar, G or send Email.. HPLC of Formula: C12H9NO

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Cinarli, M; Cinarli, E; Ataol, CY; Idil, O; Kariptas, E in ELSEVIER published article about CRYSTAL-STRUCTURE; SPECTROSCOPIC CHARACTERIZATION; INTERMOLECULAR INTERACTIONS; ANTIBACTERIAL ACTIVITY; COORDINATION BEHAVIOR; BIOLOGICAL-ACTIVITY; CHEMICAL ACTIVITY; DIAZO-COMPOUNDS; SCHIFF-BASES; X-RAY in [Cinarli, Murat] Ahi Evran Univ, Cent Res & Applicat Lab, TR-40100 Kirsehir, Turkey; [Cinarli, Esra] Ahi Evran Univ, Fac Sci, Dept Biol, TR-40100 Kirsehir, Turkey; [Ataol, Cigdem Yuksektepe] Cankiri Karatekin Univ, Fac Sci, Dept Phys, TR-18100 Cankiri, Turkey; [Idil, Onder] Amasya Univ, Fac Educ, Dept Basic Educ, TR-05000 Amasya, Turkey; [Kariptas, Ergin] Ahi Evran Univ, Fac Med, Dept Microbiol, TR-40100 Kirsehir, Turkey in 2019.0, Cited 65.0. Computed Properties of C12H9NO. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

The NNO tridentate Schiff base ligand of 2-benzoyl pyridine sulfonyl hydrazone (HL) and its transition metal complexes [CoL2] (1), [NiL2] (2) and [ZnL2] (3) have been synthesized and characterized by analytical and spectroscopic studies. The molecular structures of HL and [NiL2] (2) have been investigated by X-ray diffraction and DET/B3LYP methods. Based on the optimized structures, a single point energy calculation was made for HL and (2) in the different solvent media. The stability of the molecular structures was investigated in different solvent environments by calculating the molecular orbital energies and total energies of the molecular structures. The global reactivity parameters were obtained and the interactions between the molecules with DNA bases such as adenine, cytosine, guanine, and thymine were investigated by using the ECT (electrophilicity-based charge transfer) method and Delta N (charge transfer). Hirshfeld surfaces of HL and (2) complex were investigated and the interaction energies between the molecules participating in C-H center dot center dot center dot O/pi interactions in the molecular structures were calculated by using the CE-HF energy model. From elemental analysis data, the metal-ligand ratio of the complexes was found to be 1:2. All compounds were examined for their antimicrobial activity against pathogenic microorganisms by the well-diffusion method. DNA cleavage studies of compounds were screened by the agarose gel electrophoresis method. The results showed that complex (3) showed highly nicking activity, while HL, (1) and (2) complexes didn’t show any nicking activity. (C) 2019 Elsevier B.V. All rights reserved.

Computed Properties of C12H9NO. About Phenyl(pyridin-2-yl)methanone, If you have any questions, you can contact Cinarli, M; Cinarli, E; Ataol, CY; Idil, O; Kariptas, E or concate me.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Authors Yang, SL; Yan, BX; Zhong, L; Jia, CQ; Yao, D; Yang, CL; Sun, K; Li, G in ROYAL SOC CHEMISTRY published article about BOND FUNCTIONALIZATION; CARBOXYLIC-ACIDS; TERT-ALKYLATION; ARENES; ACTIVATION; ARYLATION; RUTHENIUM(II); OLEFINATION; INHIBITORS; NITRATION in [Yang, Suling; Yan, Bingxu; Zhong, Lei; Yao, Dan; Yang, Chunli; Sun, Kai; Li, Gang] Anyang Normal Univ, Coll Chem & Chem Engn, Henan Prov Key Lab New Optoelect Funct Mat, Anyang 455002, Peoples R China; [Jia, Chunqi] Huaqiao Univ, Sch Biomed Sci, Key Lab Xiamen Marine & Gene Drugs, Engn Res Ctr Mol Med,Minist Educ,Key Lab Fujian M, Xiamen 361021, Peoples R China in 2020.0, Cited 75.0. SDS of cas: 91-02-1. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1

Themeta-C-Ar-H alkylation of arenes with radicals produced from AIBN in the presence of a RuCl(3)catalyst is presented. This development not only confirmed that ruthenium-catalyzedmeta-C-Ar-H bond functionalization is a radical process, but also provided an efficient and practical strategy for the preparation of aromatic compounds containing a nitrile group, which are prevalent in a diverse range of biologically active molecules and other functional materials.

SDS of cas: 91-02-1. Welcome to talk about 91-02-1, If you have any questions, you can contact Yang, SL; Yan, BX; Zhong, L; Jia, CQ; Yao, D; Yang, CL; Sun, K; Li, G or send Email.

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem

Name: Phenyl(pyridin-2-yl)methanone. In 2020.0 APPL ORGANOMET CHEM published article about ASYMMETRIC TRANSFER HYDROGENATION; N-HETEROCYCLIC CARBENE; PYRAZOLYL-IMIDAZOLYL LIGAND; CATALYTIC-ACTIVITY; BEARING; KETONES; EFFICIENT; CONSTRUCTION; NITRILES; IMPACT in [Singh, Prasoon Raj; Maji, Ankur; Singh, Ovender; Singh, Udai P.; Ghosh, Kaushik] IIT Roorkee, Dept Chem, Roorkee 247667, Uttarakhand, India in 2020.0, Cited 59.0. The Name is Phenyl(pyridin-2-yl)methanone. Through research, I have a further understanding and discovery of 91-02-1.

Ruthenium complexes(1-3) have been synthesized using pincer-type ligands L-1 = (E)-2-((2-phenyl-2-(pyridin-2-yl)hydrazono)methyl)pyridine, L-2 = (E)-2-(1-phenyl-2-(1-(pyridin-2-yl)ethylidene)hydrazinyl)pyridine, L-3 = (E)-2-(phenyl(2-phenyl-2-(pyridin-2-yl)hydrazono) methyl)pyridine. The molecular structures of all the complexes 1, 2 and 3 were determined by using single crystal X-ray diffraction. These complexes showed excellent catalytic activities such as transfer hydrogenation and alcohol oxidation. Theoretical calculations have been performed to understand the electronic properties of all the complexes using B3LYP as a function and LANL2DZ as a basis set.

Welcome to talk about 91-02-1, If you have any questions, you can contact Singh, PR; Maji, A; Singh, O; Singh, UP; Ghosh, K or send Email.. Name: Phenyl(pyridin-2-yl)methanone

Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem