Category: 94928-86-6

《Visible-Light-Promoted Oxo-difluoroalkylation of Alkenes with DMSO as the Oxidant》 was written by Xia, Zi-Hao; Gao, Zhong-Hua; Dai, Lei; Ye, Song. Product Details of 94928-86-6This research focused onvisible light promoted oxo difluoroalkylation alkene DMSO oxidant. The article conveys some information:

Visible-light-promoted oxo-difluoroalkylation (acetylation and acetamidation) of alkenes with DMSO as both the solvent and the oxidant was developed, affording the corresponding α,α-difluoro-γ-ketoacetates and acetamides in modest yields. Both terminal and internal alkenes worked well for the reaction. This reaction features simple starting materials, a green oxidant, mild reaction conditions, and highly functional products. The experimental part of the paper was very detailed, including the reaction process of fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Product Details of 94928-86-6)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Product Details of 94928-86-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Chen, Pu; Chen, Zan; Xiong, Bi-Quan; Liang, Yun; Tang, Ke-Wen; Xie, Jun; Liu, Yu published their research in Organic & Biomolecular Chemistry in 2021. The article was titled 《Visible-light-mediated cascade cyanoalkylsulfonylation/cyclization of alkynoates leading to coumarins via SO2 insertion》.Formula: C33H24IrN3 The article contains the following contents:

A visible-light-mediated tandem cyanoalkylsulfonylation/cyclization of alkynoates with cycloketone oxime compounds for the preparation of 3-cyanoalkylsulfonylcoumarins I [R1 = H, 6-Me, 7-OMe, etc.; R2 = Me, Ph, 2-thienyl, etc.; R3 = H, Ph, 4-MeC6H4, etc.; R4 = H, Me; R5 = H, Bn] via SO2 insertion was reported. The difunctionalization of carbon-carbon triple bonds includes a radical mechanism and involved the formation of an iminyl radical, ring-opening of the cycloketone, insertion of SO2, addition of the sulfonyl radical to carbon-carbon triple bonds, ipso-cyclization and ester migration. In the experiment, the researchers used many compounds, for example, fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Formula: C33H24IrN3)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Formula: C33H24IrN3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Wang, Yu-Zhao; Lin, Wu-Jie; Liu, Hong-Chao; Yu, Wei published an article in Organic Chemistry Frontiers. The title of the article was 《Visible-light-promoted radical amidoarylation of arylacrylamides towards amidated oxindoles》.Product Details of 94928-86-6 The author mentioned the following in the article:

A visible-light-promoted intermol. radical amidation/cyclization of arylacrylamides was realized by using N-aminopyridinium salts as the source of amidyl radicals. The reaction exhibited a broad scope and good functional group tolerance and a variety of amide-tethered-oxindoles were prepared in this way in moderate to good yields. In the experiment, the researchers used many compounds, for example, fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Product Details of 94928-86-6)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. Product Details of 94928-86-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Electric Literature of C33H24IrN3In 2021 ,《Photocatalytic Radical Ortho-Dearomative Cyclization: Access to Spiro[4.5]deca-1,7,9-trien-6-ones》 was published in Journal of Organic Chemistry. The article was written by Dong, Wuheng; Yuan, Yao; Liang, Caiyun; Wu, Feng; Zhang, Siyuan; Xie, Xiaomin; Zhang, Zhaoguo. The article contains the following contents:

A highly efficient ortho-dearomative cyclization reaction between alkynes and 2-bromo-2-(2-methoxybenzyl)malonates via visible light-induced photoredox catalysis has been reported. In the presence of 1 mol% fac-Ir(ppy)3, a variety of spiro[4.5]deca-1,7,9-trien-6-ones, e.g., I, was obtained in moderate to excellent yields under mild conditions. Under the optimized reaction conditions, a sample reaction of 3 mmol scale proceeded smoothly to give the desired products in 84% yield with a low catalyst loading of 0.1 mol%. In the experiment, the researchers used fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Electric Literature of C33H24IrN3)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Electric Literature of C33H24IrN3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Visible-Light-Induced Intermolecular Dearomative Cyclization of Furans: Synthesis of 1-Oxaspiro[4.4]nona-3,6-dien-2-one》 was written by Dong, Wuheng; Yuan, Yao; Gao, Xiaoshuang; Keranmu, Miladili; Li, Wanfang; Xie, Xiaomin; Zhang, Zhaoguo. Recommanded Product: fac-Tris(2-phenylpyridine)iridiumThis research focused onvisible light intermol dearomative cyclization furan iridium catalyst alkyne; spirolactone preparation. The article conveys some information:

A fac-Ir(ppy)3-catalyzed intermol. dearomative cyclization of 2-bromo-2-((5-bromofuran-2-yl)methyl)malonate and alkynes affording substituted spirolactones, e.g. I, in yields of 19-91% via a 5-exo-dig radical cyclization under visible light is presented. This method provides a new access to the synthesis of spirocycle skeletons applying water as an external oxygen source under mild reaction conditions. In the experiment, the researchers used fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Recommanded Product: fac-Tris(2-phenylpyridine)iridium)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Recommanded Product: fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Synthesis of Functionalized Spirocyclic Indolines by Visible Light-Induced One-Pot Sequential Difluoromethylative Dearomatization, Hydroxylation, and Substitution Reactions》 were Wang, Qiang; Qu, Yi; Liu, Yuxiu; Song, Haibin; Wang, Qingmin. And the article was published in Advanced Synthesis & Catalysis in 2019. Name: fac-Tris(2-phenylpyridine)iridium The author mentioned the following in the article:

Herein an one-pot protocol for visible light-induced synthesis of functionalized spirocyclic indolines I [R = P(O)Ph2, 2-pyrrolyl, 3-indolyl, etc.; R1 = H, 5-F, 6-Me, etc.] was described under mild conditions by means of a process involving sequential difluoromethylative dearomatization, hydroxylation and substitution reactions of indole derivatives The transformation proceeded via a hydroxylated “”acetal pool”” intermediate that could react with various nucleophiles. Several of the phosphine-oxide and indole-substituted products showed good fungicidal activity, suggesting that this protocol might be useful in the agrochem. field. The results came from multiple reactions, including the reaction of fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Name: fac-Tris(2-phenylpyridine)iridium)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Name: fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ji, Wen-Zhe; Shi, Hao-Nan; Wei, Ping; Hao, Wen-Juan; Tu, Shu-Jiang; Jiang, Bo published their research in Advanced Synthesis & Catalysis in 2021. The article was titled 《Photocatalytic Annulation-Carbohalogenation of 1,7-Enynes for Atom-Economic Synthesis of Functionalized 3,4-dihydronaphthalen-1(2H)-ones》.Reference of fac-Tris(2-phenylpyridine)iridium The article contains the following contents:

A general and efficient photocatalytic annulation-carbohalogenation of 1,7-enynes with a wide variety of alkyl halides were reported, which resulted in atom-economic synthesis of functionalized 3,4-dihydronaphthalen-1(2H)-ones with good yields and high stereoselectivity under the mild and oxidant-free conditions. The reaction demonstrated remarkable compatibility regarding alkyl halides as a bifunctional reagents, such as ethyl-2-bromo-2,2-difluoroacetate, ethyl-2,2-difluoro-2-iodoacetate, perfluorobutyl iodide, bromotrichloromethane, and diethyl-2-bromomalonate, and which provided wide substrate scope, high functional group tolerance, and 100% atom utilization.fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Reference of fac-Tris(2-phenylpyridine)iridium) was used in this study.

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Reference of fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Trifluoromethylation/Difluoromethylation-Initiated Radical Cyclization of o-Alkenyl Aromatic Isocyanides for Direct Construction of 4-Cyano-2-Trifluoromethyl/Difluoromethyl-Containing Quinolines》 was written by Mao, Shukuan; Wang, He; Liu, Lu; Wang, Xin; Zhou, Ming-Dong; Li, Lei. Name: fac-Tris(2-phenylpyridine)iridium And the article was included in Advanced Synthesis & Catalysis in 2020. The article conveys some information:

A radical-triggered cyclization of o-alkenyl aromatic isocyanides prepared from accessible starting materials was developed. The reaction provided a general and efficient method for the synthesis of 4-CN-2-CF3/CF2H-containing quinolines under copper or visible-light photoredox catalysis in a one-pot synthetic procedure. This protocol demonstrated good to high yields, broad substrate scope, and good functional group tolerance. The experimental process involved the reaction of fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Name: fac-Tris(2-phenylpyridine)iridium)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Name: fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Takashima, Chinami; Seino, Junji; Nakai, Hiromi published an article in 2021. The article was titled 《Database-assisted local unitary transformation method for two-electron integrals in two-component relativistic calculations》, and you may find the article in Chemical Physics Letters.Safety of fac-Tris(2-phenylpyridine)iridium The information in the text is summarized as follows:

This letter presents an efficient algorithm for local unitary transformation based on the spin-free infinite-order two-component relativistic method for the two-electron interaction, which is assisted by one-center relativistic two-electron integral (TEI) database. The database stores a set of TEIs, one for each element-basis set combination. The algorithm is numerically assessed for hydrogen halide chains, (HX)n (X = Cl and At), Aun, Ir(ppy)3, Pt3(C7H7)2(HCN)3, and PtCl2(NH3)2. The computational cost (time and memory size) at the Hartree-Fock level is lower than that of the conventional method, especially for small and medium-sized mols.fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Safety of fac-Tris(2-phenylpyridine)iridium) was used in this study.

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Safety of fac-Tris(2-phenylpyridine)iridium

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Formula: C33H24IrN3In 2019 ,《Merging Visible-Light Photoredox and Organoamine Catalysis for the C-3 Difluoroalkylation of Quinoxalin-2(1H)-Ones》 appeared in Asian Journal of Organic Chemistry. The author of the article were Jin, Can; Zhuang, Xiaohui; Sun, Bin; Li, Deyu; Zhu, Rui. The article conveys some information:

A mild and efficient protocol for visible-light and organoamine cocatalyzed difluoroalkylation of quinoxalin-2(1H)-ones with functionalized difluoromethyl bromides was developed. The transformation was carried out at room temperature and gave a variety of C-3 difluoroalkylated quinoxaline-2(1H)-ones in moderate to excellent yields. Moreover, mechanistic studies revealed that this transformation proceeded through a radical-type debrominative coupling process with only need of catalytic amount of diisopropylethylamine (DIPEA). This strategy featured wide functional group tolerance, excellent regioselectivity, mild conditions and operational simplicity. In the experiment, the researchers used fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6Formula: C33H24IrN3)

fac-Tris(2-phenylpyridine)iridium(cas: 94928-86-6) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Formula: C33H24IrN3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem