Category: pyridine-derivatives

Billingsley, Kelvin L. published the artcileA general and efficient method for the Suzuki-Miyaura coupling of 2-pyridyl nucleophiles, Formula: C5H6BNO2, the publication is Angewandte Chemie, International Edition (2008), 47(25), 4695-4698, database is CAplus and MEDLINE.

One of the most general systems for the cross-coupling of aryl and heteroaryl bromides and chlorides R¹X (R¹ = 4-n-BuC₆H₄, 2,5-Me₂C₆H₃, 3-pyridyl, 5-pyrimidyl, 4-isoquinolinyl, etc.; X = Cl, Br) with 2-pyridyl-derived nucleophiles R²B(OCHMe₂)₃Li [R² = 2-pyridyl, 5-fluoro-2-pyridyl, 6-methoxy-2-pyridyl, 6-(1,3-dioxolan-2-yl)-2-pyridyl] with formation of 2-aryl-substituted pyridines has been developed. The best catalysts were comprised from [Pd₂(dba)₃] and either di-Ph or di(tert-butyl) phosphine oxide.

Angewandte Chemie, International Edition published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Formula: C5H6BNO2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lamers, Philip published the artcileBenzo[c]isothiazole 2-Oxides: Three-Dimensional Heterocycles with Cross-Coupling and Functionalization Potential, Name: 2-Bromopyridin-3-amine, the publication is Advanced Synthesis & Catalysis (2016), 358(22), 3649-3653, database is CAplus.

A robust method for the synthesis of benzo[c]isothiazole 2-oxides has been developed providing a range of functionalized derivatives starting from anilines and DMSO. The reaction sequence can be performed on a gram scale and leads to products that can easily be modified by standard cross-coupling reactions.

Advanced Synthesis & Catalysis published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Name: 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Cappello, Daniela published the artcileDual Emission, Aggregation, and Redox Properties of Boron Difluoride Hydrazones Functionalized with Triphenylamines, HPLC of Formula: 91-02-1, the publication is ChemPhotoChem, database is CAplus.

π-Conjugated mol. materials often exhibit interesting photoluminescence, redox, and optoelectronic properties that grant them utility as light-harvesting materials in solar cells, as the emissive component of organic light-emitting diodes, and as fluorescence sensors. Preparing dye conjugates by appending multiple dyes together to generate π-conjugated mols. is a common strategy to enhance the properties of these materials as it often imparts traits that cannot be achieved by the building blocks independently. Herein, we report mol. materials that incorporate boron difluoride hydrazone (BODIHY) and triphenylamine (TPA) units that exhibit charge-transfer character, dual-emission, and aggregation-induced emission. The title compounds have low-energy absorption bands (λ_abs=455-493 nm) that are red-shifted relative to BODIHYs with smaller π-systems and exhibit dual-emission in the solution, solid, and aggregate states. TPA-BODIHY (donor-acceptor) conjugates show multiple reversible redox events and, in combination, the data presented herein indicate that there is electronic communication throughout the donor-acceptor and acceptor-donor-acceptor π-systems. These results are rationalized with the use of computational chem. and solid-state structural anal. This study provides new opportunities for the design of mol. materials that are comprised of redox-active photoluminescent dyes, including BODIHY, and their potential applications.

ChemPhotoChem published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C12H9NO, HPLC of Formula: 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Jimenez Plaza, J. published the artcile2-Pyridylaldehyde-2-pyridylhydrazone as an analytical reagent. V. Spectrophotometric determination of copper(II), Application of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, the publication is Boletin de la Sociedad Quimica del Peru (1980), 46(1), 94-102, database is CAplus.

2-Pyridylaldehyde-2-pyridylhydrazone reacts with Cu(II) in pH 5 buffer solution (HOAc-NaOAc) to form a 1:1 complex. The reaction can be used to determine Cu(II) by measuring the absorbance of the complex at 350-370 nm. Beer’s law is obeyed for 1-6.5 ppm Cu. Tolerance levels are given for 30 ions.

Boletin de la Sociedad Quimica del Peru published new progress about 2215-33-0. 2215-33-0 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine, name is 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine, and the molecular formula is C11H10N4, Application of 2-((2-(Pyridin-2-yl)hydrazono)methyl)pyridine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Glinkerman, Christopher M. published the artcileSynthesis, Characterization, and Rapid Cycloadditions of 5-Nitro-1,2,3-triazine, COA of Formula: C11H8N2O2, the publication is Organic Letters (2018), 20(9), 2628-2631, database is CAplus and MEDLINE.

The synthesis, characterization, and a study of the cycloaddition reactions of 5-nitro-1,2,3-triazine (I) are reported. The electron-deficient nature of I permits rapid cycloaddition with a variety of electron-rich dienophiles, including amidines, enamines, enol ethers, ynamines, and ketene acetals in high to moderate yields. ¹H NMR studies of a representative cycloaddition reaction between I and an amidine revealed a remarkable reaction rate and efficiency (1 mM, <60 s, CD₃CN, 23°, >95%).

Organic Letters published new progress about 89076-64-2. 89076-64-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Nitro Compound,Benzene, name is 5-Nitro-2-phenylpyridine, and the molecular formula is C11H8N2O2, COA of Formula: C11H8N2O2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Bohme, Horst published the artcileAddition compounds of triphenylboron and thioethers or tertiary amines, Product Details of C23H20BN, the publication is Zeitschrift fuer Anorganische und Allgemeine Chemie (1957), 160-3, database is CAplus.

cf. C.A. 51, 13739e. NaBPh₄ in MeOH with Me₂SBr₂ at 5-10° precipitated Me₂SBPh₃ (I), m. 180°; with (iso-Pr)₂S and Br at 0° (iso-Pr)₂SBPh₃, m. 165° (decomposition); with tetrahydrothiophene dibromide at -5-0° unstable (C₄H₈S)₂BPh₃, m. 132-3°; and with PhCH₂SBr₂ at -70° in a closed system, PhCH₂SBPh₃, decomposed at room temperature With pyridine dibromide at 0° and with Et₃NBr₂, the products were colorless C₅H₅NBPh₃, m. 214° (decomposition), and Et₃NBPh₃, m. 177-8°, resp. Ph₂SBPh₃ could not be prepared in this way, nor could the thioether addition compounds be prepared by direct combination. I was insoluble in H₂O and most organic solvents and was not attacked in the cold by dilute acids or alkalies.

Zeitschrift fuer Anorganische und Allgemeine Chemie published new progress about 971-66-4. 971-66-4 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene, name is Triphenyl(pyridin-1-ium-1-yl)borate, and the molecular formula is C23H20BN, Product Details of C23H20BN.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Lamers, Philip published the artcileTetrahydrobenzo[c]thieno[2,1-e]isothiazole 4-Oxides: Three-Dimensional Heterocycles as Cross-Coupling Building Blocks, Related Products of pyridine-derivatives, the publication is Organic Letters (2018), 20(1), 116-118, database is CAplus and MEDLINE.

Tetrahydrobenzothienoisothiazole oxides such as I (R = H, I, Br, F, Cl, NC, MeO₂C, O₂N, F₅S, F₃C), cyclic sulfoximines, were prepared as novel heterocycles amenable to cross-coupling reactions and automated parallel synthesis. Reaction of tetrahydrothiophene with anilines such as 4-RC₆H₄NH₂ (R = H, I, Br, F, Cl, NC, MeO₂C, O₂N, F₅S, F₃C) mediated by N-chlorosuccinimide (NCS) and Et₃N in CH₂Cl₂ yielded (tetrahydrothienyl)anilines such as II (R = H, I, Br, F, Cl, NC, MeO₂C, O₂N, F₅S, F₃C) in 29-89% yields; tetrahydrothiopyran, N-Boc thiomorpholine, and 1,4-thioxane yielded thioether-substituted anilines, but the products did not undergo oxidative cyclocondensation. Further oxidation of (tetrahydrothienyl)anilines with N-chlorosuccinimide, treatment with aqueous NaOH, and oxidation with meta-chloroperbenzoic acid (mCPBA) yielded such as I (R = H, I, Br, F, Cl, NC, MeO₂C, O₂N, F₅S, F₃C). I (R = I, Br) and related tetrahydrobenzothienoisothiazole oxides underwent borylation, Sonogashira, and Suzuki coupling reactions.

Organic Letters published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Calugi, Lorenzo published the artcileSuzuki and Heck Processes for the Synthesis of New Anthraquinone-Based Glycoconjugated Dyes, Safety of 2-Pyridinylboronic acid, the publication is ChemistrySelect (2018), 3(8), 2235-2239, database is CAplus.

Starting from a bromo-anthraquinone dye, different aryl- and styril- derivates are obtained following Suzuki and Heck procedures. Bathochromic shifts are displayed for the products, if compared to the starting anthraquinone dye. Two of these dyes, coming from either the Suzuki and the Heck processes, have been glycosylated with a piperazinyl-lactose derivative, so that two naturalized species are finally obtained. Therefore, the disperse chromophores were transformed in water soluble direct species. These kinds of dyes allow to avoid azo- structures, that are object of growing criticism in the European Union due to their environmental impact.

ChemistrySelect published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Safety of 2-Pyridinylboronic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Biot, Nicolas published the artcileConcurring Chalcogen- and Halogen-Bonding Interactions in Supramolecular Polymers for Crystal Engineering Applications, Related Products of pyridine-derivatives, the publication is Chemistry – A European Journal (2020), 26(13), 2904-2913, database is CAplus and MEDLINE.

The engineering of crystalline mol. solids through the simultaneous combination of distinctive non-covalent interactions is an important field of research, as it could allow chemist to prepare materials depicting multi-responsive properties. It is in this context that, pushed by a will to expand the chem. space of chalcogen-bonding interactions, a concept is put forward for which chalcogen- and halogen-bonding interactions can be used simultaneously to engineer multicomponent co-crystals. Through the rational design of crystallizable mols., chalcogenazolo pyridine scaffold (CGP) modules were prepared that, bearing either a halogen-bond acceptor or donor at the 2-position, can interact with suitable complementary mol. modules undergoing formation of supramol. polymers at the solid state. The recognition reliability of the CGP moiety to form chalcogen-bonded dimers allows the formation of heteromol. supramol. polymers through halogen-bonding interactions, as confirmed by single-crystal X-ray diffraction anal.

Chemistry – A European Journal published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Related Products of pyridine-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem

Biot, Nicolas published the artcileProgramming Recognition Arrays through Double Chalcogen-Bonding Interactions, Safety of 2-Bromopyridin-3-amine, the publication is Chemistry – A European Journal (2018), 24(21), 5439-5443, database is CAplus and MEDLINE.

In this work, we have programmed and synthesized a recognition motif constructed around a chalcogenazolo-pyridine scaffold (CGP) that, through the formation of frontal double chalcogen-bonding interactions, associates into dimeric EX-type complexes. The reliability of the double chalcogen-bonding interaction has been shown at the solid-state by X-ray anal., depicting the strongest recognition persistence for a Te-congener. The high recognition fidelity, chem. and thermal stability and easy derivatization at the 2-position makes CGP a convenient motif for constructing supramol. architectures through programmed chalcogen-bonding interactions.

Chemistry – A European Journal published new progress about 39856-58-1. 39856-58-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Bromide,Amine, name is 2-Bromopyridin-3-amine, and the molecular formula is C5H5BrN2, Safety of 2-Bromopyridin-3-amine.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem