Category: pyridine-derivatives

On September 30, 2011, Borkar, Nitin; Sawant, Sakshi published an article.Application of 132-20-7 The title of the article was Review of simultaneous determination of analytes by high performance liquid chromatography (HLPC) in multicomponent cough and cold oral drug products. And the article contained the following:

A review. The objective of this article is to review the methodologies of determination of the most widely used analytes in cough and cold preparations by HPLC. This article studies the effect of all chromatog. parameters so as to provide a fast, reliable and cost effective methodol. of testing. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).Application of 132-20-7

The Article related to review cough cold oral drug analysis hplc, Pharmaceutical Analysis: Reviews and other aspects.Application of 132-20-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On December 1, 1995, Tanaka, Shunitz; Kodama, Kokoro; Kaneta, Takashi; Nakamura, Hiroshi published an article.Application In Synthesis of Pyridine-3-sulfonic acid The title of the article was Migration behavior of niacin derivatives in capillary electrophoresis. And the article contained the following:

The migration behavior of niacin derivatives was investigated by capillary zone electrophoresis (CZE) and micellar electrokinetic chromatog. (MEKC). When the pH of the buffer solution is lower than the pKa of the pyridine ring in the niacin derivatives, they are pos. charged by protonation on the pyridine ring and migrate electrophoretically. The mobilities of niacin derivatives in CZE were controlled by the pH of the migrating buffer. Good separation of 13 niacin derivatives was achieved at pH 2.8. Further, to shorten the anal. time and to achieve a more complete separation, an investigation by MEKC using SDS micelles was performed. All 13 niacin derivatives were eluted within 30 min and a satisfactory separation was achieved. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Application In Synthesis of Pyridine-3-sulfonic acid

The Article related to niacin derivative migration capillary zone electrophoresis, micellar electrokinetic chromatog niacin derivative, Biochemical Methods: Electrical and other aspects.Application In Synthesis of Pyridine-3-sulfonic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Xing, Kai; Fan, Rui-Qing; Liu, Xiao-Yuan; Gai, Shuang; Chen, Wei; Yang, Yu-Lin; Li, Jing published an article in 2020, the title of the article was A self-calibrating dual responsive platform for the sensitive detection of sulfite and sulfonic derivatives based on a robust Hf(IV) metal-organic framework.Name: Pyridine-3-sulfonic acid And the article contains the following content:

A robust hafnium-based metal organic framework, Hf-PBTA, with sensitive and self-calibrating dual-emissive fluorescence response towards sulfite and sulfonic derivatives, including antibiotic sulfamethazine, has been developed, which shows fast detection of sulfite ions at a concentration as low as 76 ppb. The opposite response tendency from two radiative pathways towards aromatic sulfonic mols. and sulfite anions stems from the synergistic effect of the pyridine protonation effect, π-π stacking interaction and intramol. twist motion. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Name: Pyridine-3-sulfonic acid

The Article related to fluorescent sensor sulfite sulfonic derivative metal organic framework, Organic Analytical Chemistry: Determinations and other aspects.Name: Pyridine-3-sulfonic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Liu, Jian-Qiang; Li, Xue-Feng; Gu, Chu-Ying; da Silva, Julio C. S.; Barros, Amanda L.; Alves, Severino Jr.; Li, Bao-Hong; Ren, Fei; Batten, Stuart R.; Soares, Thereza A. published an article in 2015, the title of the article was A combined experimental and computational study of novel nanocage-based metal-organic frameworks for drug delivery.Quality Control of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid And the article contains the following content:

Three new metal organic frameworks (MOFs) with chem. formulas [(CH3)2NH2] [Sm3(L1)2(HCOO)2(DMF)2(H2O)]·2DMF·18H2O (1), [Cu2(L2)(H2O)2]·2.22DMA (2) and [Zn2(L1)(DMA)]·1.75DMA were synthesized and structurally characterized. 1 and 2 show a classical NbO-like topol. and have two types of interconnected cages. 3 exhibits an uncommon zzz topol. and has two types of interconnected cages. These MOFs can adsorb large amounts of the drug 5-fluorouracil (5-FU) and release it in a progressive way. 5-FU was incorporated into desolvated 1, 2 and 3 with loadings of 0.40, 0.42, and 0.45 g g-1, resp. The drug release rates were 72%, 96% and 79% of the drug after 96 h in 1, 120 h in 2 and 96 h in 3, resp. Grand Canonical Monte Carlo (GCMC) simulations were performed to investigate the mol. interactions during 5-FU adsorption to the three novel materials. The GCMC simulations reproduced the exptl. trend with respect to the drug loading capacity of each material. They also provided a structural description of drug packing within the frameworks, helping to explain the load capacity and controlled release characteristics of the materials. 5-FU binding preferences to 1, 2 and 3 reflect the diversity in pore types, chem. and sizes. The calculated drug load is more related to the mol. properties of accessible volume Vacc than to the pore size. The experimental process involved the reaction of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid(cas: 1431292-15-7).Quality Control of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid

The Article related to nanocage metal organic framework preparation 5fu drug delivery cancer, Pharmaceuticals: Formulation and Compounding and other aspects.Quality Control of 5,5′-(Pyridine-2,5-diyl)diisophthalic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Eltsova, Natalia O.; Budko, Elena V.; Yampolskii, Leonid M.; Kulikov, Alexander L. published an article in 2016, the title of the article was UPLC study of inter-component interaction in the system “naproxen – pheniramine maleate”.Computed Properties of 132-20-7 And the article contains the following content:

The anal. was performed for the two-component system “naproxen – pheniramine maleate” using the method UPLC. It is concluded that strengthening the destructive processes in the presence of pheniramine maleate with naproxen based on the chromatogram initial substances at influence of stress factors and identified degradation products. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).Computed Properties of 132-20-7

The Article related to naproxen pheniramine maleate inter component interaction uplc, Pharmaceuticals: Formulation and Compounding and other aspects.Computed Properties of 132-20-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On August 13, 2012, Zhao, Hong-Wu; Li, Hai-Long; Yue, Yuan-Yuan; Qin, Xiao; Sheng, Zhi-Hui; Cui, Jin; Su, Shi; Song, Xiu-Qing; Yan, Hong; Zhong, Ru-Gang published an article.Safety of [2,2′-Bipyridine]-3,3′-diamine The title of the article was Design, synthesis and use of novel 3,3′-disubstituted 2,2′-bipyridine-based chiral ligands: asymmetric catalysis in direct aldol reactions. And the article contained the following:

A wide range of chiral ligands based on the 2,2′-bipyridine scaffold were designed and synthesized. In complexation with metal Lewis acids, the reactivity and stereoselectivity of the prepared chiral ligands were examined in asym. catalytic direct aldol reactions, thus providing the desired products with high stereoselectivities. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Safety of [2,2′-Bipyridine]-3,3′-diamine

The Article related to bipyridine chiral ligand preparation asym aldol catalyst, General Organic Chemistry: Synthetic Methods and other aspects.Safety of [2,2′-Bipyridine]-3,3′-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Bukhari, Syed Majid Hanif; Khan, Samiullah; Rehanullah, Muhammad; Ranjha, Nazar Mohammad published an article in 2015, the title of the article was Synthesis and characterization of chemically cross-linked acrylic acid/gelatin hydrogels: effect of pH and composition on swelling and drug release.Category: pyridine-derivatives And the article contains the following content:

This present work was aimed at synthesizing pH-sensitive cross-linked AA/Gelatin hydrogels by free radical polymerization Ammonium persulfate and ethylene glycol dimethacrylate (EGDMA) were used as initiator and as crosslinking agent, resp. Different feed ratios of acrylic acid, gelatin, and EGDMA were used to investigate the effect of monomer, polymer, and degree of crosslinking on swelling and release pattern of the model drug.The swelling behavior of the hydrogel samples was studied in 0.05M USP phosphate buffer solutions of various pH values pH 1.2, pH 5.5, pH 6.5, and pH 7.5.The prepared samples were evaluated for porosity and sol-gel fraction anal. Pheniraminemaleate used for allergy treatment was loaded as model drug in selected samples. The release study of the drug was investigated in 0.05M USP phosphate buffer of varying pH values (1.2, 5.5, and 7.5) for 12 h. The release data was fitted to various kinetic models to study the release mechanism. Hydrogels were characterized by Fourier transformed IR (FTIR) spectroscopy which confirmed formation of structure. Surface morphol. of unloaded and loaded samples was studied by surface electron microscopy (SEM), which confirmed the distribution of model drug in the gel network. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).Category: pyridine-derivatives

The Article related to acrylic acid gelatin hydrogel drug delivery system, Pharmaceuticals: Formulation and Compounding and other aspects.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On March 31, 2010, Rajalakshmi, G.; Damodharan, N.; Chaudhary, Abhinav; Maheswara Reddy, D. published an article.COA of Formula: C20H24N2O4 The title of the article was Formulation and evaluation of Orodispersible tablets of Pheniramine maleate. And the article contained the following:

In the present study an attempt has been made to formulate Pheniramine maleate a selective H1 receptor antagonist into orodispersible tablet. The tablets were prepared by direct compression method using super disintegrants like croscarmellose sodium, crospovidone, sodium starch glycollate, low hydroxyl pr cellulose and pre gelatinized starch in different ratios. The blend was examined for various pre compression parameters. Tablets were evaluated by measuring hardness, friability, content uniformity, weight variation and drug release pattern. All the tablets met the pharmacopoeial requirements for phys. tests. Almost in all the formulations with increase in concentration of superdisintegrants, the drug release was rapid. Stability studies were also performed. Dissolution studies indicated that the tablets containing crospovidone and croscarmellose sodium showed rapid dissolution compared to other disintegrants releasing almost 100% of the drug in six minutes. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).COA of Formula: C20H24N2O4

The Article related to pheniramine maleate orodispersible tablet, Pharmaceuticals: Formulation and Compounding and other aspects.COA of Formula: C20H24N2O4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 1, 2020, Tozaki, Keiki; Tatara, Kazuyoshi; Nishiyama, Yugo published a patent.Product Details of 52243-87-5 The title of the patent was Heat storage material comprising viologen compound. And the patent contained the following:

The invention relates to a heat storage material capable of suppressing super cooling with only one kind of organic heat storage material. The heat storage material comprises: a viologen-based compound represented by a general formula I; where R is C3-18 aliphatic alkyl group, X is halogen or bis(trifluoromethanesulfonyl)imide. The heat storage material has ≤30°C of a m.p.-f.p. temperature difference ΔTm-Tf; where Tm is a temperature at which it melts when heated to become an isotropic liquid; and Tf is a temperature at which the isotropic liquid solidifies during cooling. The experimental process involved the reaction of 1,1′-Dipropyl-[4,4′-bipyridine]-1,1′-diium bromide(cas: 52243-87-5).Product Details of 52243-87-5

The Article related to viologen compound heat storage material, Unit Operations and Processes: Heat Transfer and other aspects.Product Details of 52243-87-5

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Petkova, Valentina; Hadzhieva, Bozhidarka Radoslavova published an article in 2021, the title of the article was Pilot study of over-the-counter drugs applied among the pediatric population in Bulgaria.Application of 132-20-7 And the article contains the following content:

Herbal medicines have evolved through their traditional use in a specific or cultural context. The pharmacol. effects of herbal medicines are not due to their “natural” origin, but to the complex character of biol. active substances. Pediatricians have begun to integrate the use of complementary / alternative medical therapies with conventional health care. The first aim of the study was to make an anal. of over-the-counter (OTC) drugs (OTCDs) with a plant component. The secondary aim was to investigate OTCDs in terms of composition and nosol. for use by the pediatric population in Bulgaria. Registered OTC drugs with a herbal component for children are prescribed for the treatment of colds, pain, gastrointestinal diseases, mild sleep disorders, neurovegetative dystonias and kinetosis, urinary tract inflammation, liver disease, and are also applied topically to inflammation, trauma, urticaria and scars. The experimental process involved the reaction of N,N-Dimethyl-3-phenyl-3-(pyridin-2-yl)propan-1-amine maleate(cas: 132-20-7).Application of 132-20-7

The Article related to herbal medicine counter drug pediatric population pain gastrointestinal disease, Placeholder for records without volume info and other aspects.Application of 132-20-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem