Diastereoselective Cyclization of 1,5-Dienes with the C-H Bond of Pyridine Catalyzed by a Cationic Mono(phosphinoamide) Alkyl Scandium Complex was written by Chen, Yanhui;Song, Di;Li, Jing;Hu, Xiaoyan;Bi, Xianjia;Jiang, Tao;Hou, Zhaomin. And the article was included in ChemCatChem in 2018.Name: 2-Isopropylpyridine This article mentions the following:
Novel rare-earth dialkyl complexes bearing a phosphinoamide anion and demonstrate that the combination of a mono(phosphinoamido)-ligated scandium dialkyl complex with B(C6F5)3 results in an excellent catalyst for the cis-selective cyclization of 1,5-dienes with the ortho-C(sp2)-H bond of pyridines to afford a new family of pyridyl-functionalized 1,3-disubstituted cyclopentane derivatives containing monocyclic, bicyclic, spirocyclic, and heterocyclic skeletons in moderate to excellent yields with high diastereoselectivities (cis/trans up to 99:1). In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Name: 2-Isopropylpyridine).
2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Name: 2-Isopropylpyridine