1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.COA of Formula: C7H7ClN2
Synthesis of 3-aminochromenes: the Zincke reaction revisited was written by Costa, Marta;Rodrigues, Ana I.;Proenca, Fernanda. And the article was included in Tetrahedron in 2014.COA of Formula: C7H7ClN2 This article mentions the following:
3-(Amino)coumarin derivatives and 2-(imino)-3-chromenamine derivatives were efficiently prepared by a Zincke-reaction-ring-opening reaction of the corresponding 2H-chromene-3-pyridinium chlorides using N-methylpiperazine. This methodol. unravels the marked potential of pyridinium salts as protective groups for primary amines. These scaffolds can be considered important building blocks for N-[7-[[3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-α-L–lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-buten-1-yl)benzamide (novobiocin) analogs and similar heterocyclic compounds The synthesis of the target compounds was achieved by a cyclization (heterocyclization, Zincke reaction) of 2-hydroxybenzoic acid derivatives with 1-(cyanomethyl)pyridinium chloride. The title compounds thus formed included 1-(2-imino-2H-1-benzopyran-3-yl)pyridinium chloride derivatives (chromene-imine derivatives) and 1-(2-oxo-2H-1-benzopyran-3-yl)pyridinium chloride derivatives (coumarin derivatives). These compounds was intermediates for 3-amino-2H-1-benzopyran-2-one derivatives (amine-coumarin derivatives) and 2-(imino)-2H-1-benzopyran-3-amine derivatives In the experiment, the researchers used many compounds, for example, 1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3COA of Formula: C7H7ClN2).
1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.COA of Formula: C7H7ClN2
Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem