The selenium dioxide oxidation of 2,3- and 3,4-dimethylpyridines was written by Dunn, A. D.. And the article was included in Organic Preparations and Procedures International in 1999.Application In Synthesis of Methyl 3-methylpicolinate This article mentions the following:
The SeO2 oxidation of 2,3-dimethylpyridine gave 3-methyl-2-pyridinecarboxaldehyde and 3-methyl-2-pyridinecarboxylic acid, isolated as its Me ester. The aldehyde was converted to its oxime which was dehydrated to the carbonitrile. 3,4-Dimethylpyridine similarly gave 3-methylisonicotinaldehyde and the acid and nitrile. In the experiment, the researchers used many compounds, for example, Methyl 3-methylpicolinate (cas: 59718-84-2Application In Synthesis of Methyl 3-methylpicolinate).
Methyl 3-methylpicolinate (cas: 59718-84-2) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Application In Synthesis of Methyl 3-methylpicolinate