Monodisperse CuPd alloy nanoparticles as efficient and reusable catalyst for the C (sp2)-H bond activation was written by Huang, Fei;Wang, Feifan;Hu, Qiyan;Tang, Lin;Xu, Dongping;Fang, Yang;Zhang, Wu. And the article was included in Applied Organometallic Chemistry in 2021.Application In Synthesis of 2-Phenoxypyridine This article mentions the following:
Metal-catalyzed selective activation of C-H bonds is very important for the construction of a variety of biol. active mols. Supported alloy nanoparticles are of great interest in various catalytic applications due to the synergistic effects between different metals. Here, well-dispersed CuPd alloy nanoparticles supported on reduced graphene oxide (rGO) were synthesized and found to be highly efficient and recyclable catalyst for the chelation-assisted C(sp2)-H bond activation. Aromatic ketones or esters were synthesized via the cross-dehydrogenative coupling (CDC) reaction between 2-arylpyridines and alcs. or acids [e.g., 2-phenylpyridine + benzyl alc. â?I (94%)]. Moreover, the catalyst was recovered and used for five times without significantly losing activity. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Application In Synthesis of 2-Phenoxypyridine).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Application In Synthesis of 2-Phenoxypyridine