Introduction of a new synthetic route about 62020-02-4

Statistics shows that 62020-02-4 is playing an increasingly important role. we look forward to future research findings about 4-Nitropicolinamide.

Application of 62020-02-4, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.62020-02-4, name is 4-Nitropicolinamide, molecular formula is C6H5N3O3, molecular weight is 167.12, as common compound, the synthetic route is as follows.

99A was hydrogenated in MeOH with 10% Pd/C (40 mg) with a hydrogen balloon for 8 h. The Pd/C was removed by filtration. The filtrate was condensed to give 99B (80 mg, 87% yield). 1H NMR (400 MHz, Methanol-d4) delta ppm 6.65 (dd, J=5.71, 2.64 Hz, 1H) 7.27 (d, J=2.20 Hz, 1H) 8.03 (d, J=5.71 Hz, 1 H).

Statistics shows that 62020-02-4 is playing an increasingly important role. we look forward to future research findings about 4-Nitropicolinamide.

Reference:
Patent; Bristol-Myers Squibb Company; US2010/227894; (2010); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem