Importance of hydrophobic interactions in the single-chained cationic surfactant-DNA complexation was written by Lopez-Lopez, Manuel;Lopez-Cornejo, Pilar;Martin, Victoria Isabel;Ostos, Francisco Jose;Checa-Rodriguez, Cintia;Prados-Carvajal, Rosario;Lebron, Jose Antonio;Huertas, Pablo;Moya, Maria Luisa. And the article was included in Journal of Colloid and Interface Science in 2018.Recommanded Product: 104-73-4 This article mentions the following:
The goal of this work was to understand the key factors determining the DNA compacting capacity of single-chained cationic surfactants. Fluorescence, zeta potential, CD, gel electrophoresis and AFM measurements were carried out to study the condensation of the nucleic acid resulting from the formation of the surfactant-DNA complexes. The apparent equilibrium binding constant of the surfactants to the nucleic acid, Kapp, estimated from the exptl. results obtained in the ethidium bromide competitive binding experiments, can be considered directly related to the ability of a given surfactant as a DNA compacting agent. The plot of ln(Kapp) vs. ln(cmc), cmc being the critical micelle concentration, for all the bromide and chloride surfactants studied, is a reasonably good linear correlation. Hydrophobic interactions mainly control the surfactant DNA compaction efficiency. In the experiment, the researchers used many compounds, for example, 1-Dodecylpyridin-1-ium bromide (cas: 104-73-4Recommanded Product: 104-73-4).
1-Dodecylpyridin-1-ium bromide (cas: 104-73-4) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Recommanded Product: 104-73-4