Mohamed, Yasser M. A. published the artcileSynthesis, antibacterial evaluation, and docking studies of azaisoflavone analogues generated by palladium-catalyzed cross coupling, Application of 2-Pyridinylboronic acid, the publication is Monatshefte fuer Chemie (2018), 149(10), 1857-1864, database is CAplus.
Palladium-catalyzed, cross-coupling reaction of N-methyl-3-iodo-4-quinolone with boronic acids or N-methyliminodiacetic acid boronates to obtain azaisoflavone derivatives was investigated through conventional Suzuki-Miyuara coupling or by slow release strategy. It was observed that a slow release approach was a highly successful. In addition, a series of novel azaisoflavones containing alkynyl group were synthesized via Sonogashira reaction. The antibacterial activities of the all synthesized compounds were screened against series of bacterial strains. Furthermore, a mol. docking study was carried out for the most active compounds using Leadit 2.1.8 docking software, and the results were in good agreement with the exptl. data. The details of synthetic methods, spectroscopic data, and biol. results were reported.
Monatshefte fuer Chemie published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Application of 2-Pyridinylboronic acid.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem