Tetraalkylammonium-based ionic liquids for a RuCl3 catalyzed C-H activated homocoupling was written by Muntzeck, Maren;Pippert, Felix;Wilhelm, Rene. And the article was included in Tetrahedron in 2020.Application of 4373-61-9 This article mentions the following:
[BuEt3N][NTf2] Could be a superior ionic liquid in a RuCl3 catalyzed oxidative C-H activation reaction compared to standard imidazolium-based ionic liquids The tetraalkylammonium-based ionic liquid resulted in higher yields. This could be due to the absence of a possible C-H activation on the tetraalkylammonium-based ionic liquid itself. This side reaction could occur with imidazolium-based ionic liquids The ionic liquid could be recycled and different oxidation agents could be used in the reaction. The best results were obtained with FeCl3 · 6H2O and with a combination of LiCl under an oxygen atm. Up to 83% yield were obtained in the homocoupling of 2-arylpyridines. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Application of 4373-61-9).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Application of 4373-61-9