Reference of 884494-69-3, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 884494-69-3, name is 3-Fluoro-2-methoxypyridine. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of 3-fluoro-2-methoxypyridine (20g, 157.48mmol), sodium acetate (25.74g, 314.0 mmol) inAcOH (6OmL) was added dropwise a solution of Br2 (20.32mL, 393.70mmol) in AcOH (40 mL) at 10Cand the RM stirred at RT for 16h.The RM was quenched into ice water (200mL) and then basified with 6N NaOH solution to pH 9 and filtered the solid. The solid was dissolved in Et2O (300mL), washed with brine, dried (Na2SO4), filtered, concentrated under reduced pressure to give 5-bromo-3-fluoro-2- methoxypyridine (20g, 61%) as white solid
According to the analysis of related databases, 884494-69-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GRUeNENTHAL GMBH; SCHUNK, Stefan; REICH, Melanie; JAKOB, Florian; DAMANN, Nils; HAURAND, Michael; KLESS, Achim; ROGERS, Marc; SUTTON, Kathy; WO2015/158427; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem