Adding a certain compound to certain chemical reactions, such as: 15197-75-8, 3-(2-Pyridyl)propionic Acid, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C8H9NO2, blongs to pyridine-derivatives compound. Computed Properties of C8H9NO2
General procedure: In air, a round bottom flask was charged with [Pd(mu-Cl)(Cl)(NHC)]2 (0.2 mmol, 225 mg), 2-pyridylacetic acid hydrochloride(0.4 mmol, 70 mg), KOtBu (1.0 mmol, 112 mg) and THF(2.0 mL). After stirring for 6 h at room temperature, the mixturewas condensed under vacuum. The solid residue was filtered byflash chromatography on short silica gel with CH2Cl2 and recrystallizedfrom n-hexane/CH2Cl2 to provide the desired products.
The synthetic route of 15197-75-8 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Chen, Wei; Yang, Jin; Journal of Organometallic Chemistry; vol. 872; (2018); p. 24 – 30;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem