Application of 6602-54-6, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 6602-54-6, Name is 2-Chloronicotinonitrile, SMILES is C1=C(C(=NC=C1)Cl)C#N, belongs to pyridine-derivatives compound. In a article, author is Lou, Shao-Jie, introduce new discover of the category.
Enantioselective C-H Alkenylation of Ferrocenes with Alkynes by Half-Sandwich Scandium Catalyst
The enantioselective C-H alkenylation of ferrocenes with alkynes is, in principle, a straightforward and atom-efficient route for the construction of planar-chiral ferrocene scaffolds bearing alkene functionality but has remained scarcely explored to date. Here we report for the first time the highly enantioselective C-H alkenylation of quinoline- and pyridine-substituted ferrocenes with alkynes by a half-sandwich scandium catalyst. This protocol features broad substrate scope, high enantioselectivity, and 100% atom efficiency, selectively affording a new family of planar-chiral ferrocenes bearing N/alkene functionalities. The mechanistic details have been clarified by DFT analyses. The use of a quinoline/alkene-functionalized ferrocene product as a chiral ligand for asymmetric catalysis is also demonstrated.
Application of 6602-54-6, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 6602-54-6 is helpful to your research.
Reference:
Pyridine – Wikipedia,
,Pyridine | C5H5N – PubChem