Synthesis, antifungal, haemolytic and cytotoxic activities of a series of bis(alkylpyridinium)alkanes was written by Obando, Daniel;Pantarat, Namfon;Handke, Rosemary;Koda, Yasuko;Widmer, Fred;Djordjevic, Julianne T.;Ellis, David H.;Sorrell, Tania C.;Jolliffe, Katrina A.. And the article was included in Bioorganic & Medicinal Chemistry in 2009.SDS of cas: 27876-24-0 This article mentions the following:
A series of bis(alkylpyridinium)alkanes with a twelve carbon spacer between the pos. charges was synthesized and their antifungal activity has been investigated. Compounds with 2-pentyl, 4-pentyl, 4-hexyl, 4-octyl, 4-propylbenzene, 3,4-dipentyl, 4-(5′-nonyl) and 3-Me,4-pentyl head groups were the most potent antifungal agents with MICs in the range of 1.4-2.7 μM against reference strains of both Cryptococcus neoformans and Candida albicans. In the experiment, the researchers used many compounds, for example, 4-Hexylpyridine (cas: 27876-24-0SDS of cas: 27876-24-0).
4-Hexylpyridine (cas: 27876-24-0) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.SDS of cas: 27876-24-0