Pyridine-derivatives

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Formula: C6H6BrN.

Zhang, Shi-Qi;Guo, Bin;Xu, Ze;Li, Hong-Xi;Li, Hai-Yan;Lang, Jian-Ping research published 《 Ligand-controlled phosphine-free Co(II)-catalysed cross-coupling of secondary and primary alcohols》, the research content is summarized as follows. Cobalt(II) complexes (5 mol% Co) bearing phosphine-free N N N pincer ligands efficiently catalyze C-C coupling of secondary and primary alcs. to selectively form α-alkylated ketones with a good functional group compatibility using NaOH (20 mol%) as a base at 120 °C. The NH group on the N N N-Co(II) precatalyst controlled the activity and selectivity. This simple catalytic system was also involved in the synthesis of 2-aryl quinolines, e.g., I, via the dehydrogenative annulation of 2-aminobenzyl alcs. with secondary alcs.

Formula: C6H6BrN, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Recommanded Product: 2-Amino-5-methylpyridine.

Zhang, Ruizhong;Cheng, Jun;Yang, Liuqing;Wong, Jonathan M.;Ralph Adsetts, Jonathan;Wang, Ruiyao;Liu, Jiyan;Ding, Zhifeng;Wang, Hong-Bo research published 《 Optimizing the Electrochemiluminescence of Readily Accessible Pyrido[1,2-α]pyrimidines through “Green” Substituent Regulation》, the research content is summarized as follows. Bright and low-cost emitting organic mols. are very desirable for electrochemiluminescence (ECL). Here, we report a facile one-step, three-component reaction of readily available precursors to synthesize pyrido[1,2-α]pyrimidine derivatives (1-4), all which give off green photoluminescence (PL). In contrast, the electrochem. and ECL properties of these luminophores are affected by the extent of the conjugation and the nature of the peripheral substituents. D. functional theory (DFT) calculations identified the aromatic chain substitution could extend the conjugation of pyrido[1,2-α]pyrimidine core and stabilize the electrogenerated radicals required for generation of an excited state, affording pyrido[1,2-α]pyrimidine 3 the highest ECL activity among the studied samples. ECL in annihilation route confirmed weak emission, but great improvement was made using oxidizing co-reactant species (benzoate radical from benzoyl peroxide, BPO) with an efficiency of 43% relative to that of Ru(bpy)₃(PF₆)₂. The pyrido[1,2-α]pyrimidine 3/BPO system is more robust than those of reducing co-reactant species [tri-n-propylamine radical or 2-(dibutylamino) ethanol radical] and is one of the highest among the reported organic electrochemiluminophores. ECL spectroscopy revealed that the monomeric excited states were the main species to emit light. Their straightforward, one-step, green synthesis, and their structure tunability represent significant advantages in the development of readily accessible dyes for PL and especially ECL applications.

1603-41-4, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, Recommanded Product: 2-Amino-5-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Safety of 5-Bromopicolinaldehyde.

Zhang, Min;Fan, Shiyong;Zhou, Xinbo;Xie, Fei;Li, Song;Zhong, Wu research published 《 Design, synthesis and biological evaluation of 2-hydrazinyladenosine derivatives as A_2A adenosine receptor ligands》, the research content is summarized as follows. To obtain potential A_2A adenosine receptor agonists, a series of 2-hydrazinyladenosine derivatives were synthesized and assayed for adenosine receptors activity using radioligand binding activity assays. The binding activity of the subtypes was examined, and the structure-activity relationship of this class of compounds at the A_2A receptor was investigated. A fragment-based computer-aided design method was used to modify the 2-position side chain structures with different structural fragments, and the newly generated mols. were docked to the A_2A receptor to assess scoring and screening activity. To synthesize compounds with better scoring activity, the newly synthesized compounds were tested for in vitro receptor binding activity. 2-Hydrazinyladenosine derivatives of 32 new structural types were designed and synthesized, with the most potent adenosine derivative I exhibiting a K_i value of 1.8 nM for A_2AAR and significant selectivity for the A_2A receptor compared to the A₁ receptor. In addition to, other compounds also exhibited potent A_2A receptor selectivity, with Ki values for the A_2A receptor of 6.4, 20, 67 and 6.3 nM, resp. We also found that compound II has a high A₁ receptor selectivity, with a K_i value for the A₁ receptor of 4.5 nM. Further functional assays also demonstrated that these compounds have potent A_2A receptor agonist activity. The study shows the applicability of an in silico fragment-based mol. design for rational lead optimization in A_2AAR.

Safety of 5-Bromopicolinaldehyde, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. HPLC of Formula: 16133-25-8.

Zhang, Mao-feng;Luo, Xiao-yu;Zhang, Cheng;Wang, Chao;Wu, Xi-shan;Xiang, Qiu-ping;Xu, Yong;Zhang, Yan research published 《 Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia》, the research content is summarized as follows. BRD4 plays a key role in the regulation of gene transcription and has been identified as an attractive target for cancer treatment. In this study, we designed 26 new compounds by modifying 3-ethyl-benzo[d]isoxazole core with sulfonamides. Most compounds exhibited potent BRD4 binding activities with ΔT_m values exceeding 6 °C. Two crystal structures of N-(3-Ethyl-6-methoxybenzo[d]isoxazol-5-yl)-2methoxybenzenesulfonamide and N-(3-Ethyl-6-methoxybenzo[d]isoxazol-5-yl)-4methoxybenzenesulfonamide in complex with BRD4(1) were obtained to characterize the binding patterns. Compounds N-(3-Ethyl-6-methoxybenzo[d]isoxazol-5-yl)-2methoxybenzenesulfonamide and N-(3-Ethyl-6-methoxybenzo[d]isoxazol-5-yl)-4methoxybenzenesulfonamide were effective for BRD4(1) binding and showed remarkable anti-proliferative activity against MV4-11 cells with IC₅₀ values of 0.78 and 0.87 μM. Furthermore, N-(3-Ethyl-6-methoxybenzo[d]isoxazol-5-yl)-4methoxybenzenesulfonamide (0.5-10 μM) concentration-dependently inhibited the expression levels of oncogenes including c-Myc and CDK6 in MV4-11 cells. Moreover, N-(3-Ethyl-6-methoxybenzo[d]isoxazol-5-yl)-4methoxybenzenesulfonamide (0.5-10 μM) concentration-dependently blocked cell cycle in MV4-11 cells at G₀/G₁ phase and induced cell apoptosis. Compound N-(3-Ethyl-6-methoxybenzo[d]isoxazol-5-yl)-4methoxybenzenesulfonamide may serve as a new lead compound for further drug development.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., HPLC of Formula: 16133-25-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The critical parameters of pyridine are pressure 6.70 MPa, temperature 620 K and volume 229 cm3·mol−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. In the temperature range 340–426 °C its vapor pressure p can be described with the Antoine equation.. Category: pyridine-derivatives.

Zhang, Lin;Yamazaki, Ken;Leitch, Jamie A.;Manzano, Ruben;Atkinson, Victoria A. M.;Hamlin, Trevor A.;Dixon, Darren J. research published 《 Dual catalytic enantioselective desymmetrization of allene-tethered cyclohexanones》, the research content is summarized as follows. The construction of enantioenriched azabicyclo[3.3.1]nonan-6-one heterocycles I [R = H, Ph, prop-2-en-1-yl, benzyl, etc.; X = O, 4-H₃CC₆H₄S(O)₂NH, NHS(O)₂Me, etc.] via an enantioselective desymmetrization of allene-linked cyclohexanones II, enabled through a dual catalytic system, that provides synchronous activation of the cyclohexanone with a chiral prolinamide and the allene with a copper(I) co-catalyst to deliver the stereodefined bicyclic core, is described. Successful application to oxygen analogs was also achieved, thereby providing a new enantioselective synthetic entry to architecturally complex bicyclic ethereal frameworks. The mechanistic pathway and the origin of enantio- and diastereoselectivities have been uncovered using d. functional theory (DFT) calculations

Category: pyridine-derivatives, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Name: 5-Bromo-2-fluoropyridine.

Zhang, Lei;Butler, Christopher R.;Maresca, Kevin P.;Takano, Akihiro;Nag, Sangram;Jia, Zhisheng;Arakawa, Ryosuke;Piro, Justin R.;Samad, Tarek;Smith, Deborah L.;Nason, Deane M.;O’Neil, Steven;McAllister, Laura;Schildknegt, Klaas;Trapa, Patrick;McCarthy, Timothy J.;Villalobos, Anabella;Halldin, Christer research published 《 Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity》, the research content is summarized as follows. Monoacylglycerol lipase (MAGL), a serine hydrolase extensively expressed throughout the brain, serves as a key gatekeeper regulating the tone of endocannabinoid signaling. Preclinically, inhibition of MAGL is known to provide therapeutic benefits for a number of neurol. disorders. The availability of a MAGL-specific positron emission tomog. (PET) ligand would considerably facilitate the development and clin. characterization of MAGL inhibitors via noninvasive and quant. PET imaging. Herein, we report the identification of the potent and selective irreversible MAGL inhibitor 7 (PF-06809247) as a suitable radioligand lead, which upon radiolabeling was found to exhibit a high level of MAGL specificity; this enabled cross-species measurement of MAGL brain expression (B_max), assessment of in vivo binding in the rat, and nonhuman primate PET imaging.

Name: 5-Bromo-2-fluoropyridine, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , 766-11-0.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Quality Control of 766-11-0.

Zhang, Lei;Hu, Xile research published 《 Nickel catalysis enables convergent paired electrolysis for direct arylation of benzylic C-H bonds》, the research content is summarized as follows. Convergent paired electrosynthesis is an energy-efficient approach in organic synthesis; however, it is limited by the difficulty to match the innate redox properties of reaction partners. Here we use nickel catalysis to cross-couple the two intermediates generated at the two opposite electrodes of an electrochem. cell, achieving direct arylation of benzylic C-H bonds. This method yields a diverse set of diarylmethanes, which are important structural motifs in medicinal and materials chem. Preliminary mechanistic study suggests oxidation of a benzylic C-H bond, Ni-catalyzed C-C coupling, and reduction of a Ni intermediate as key elements of the catalytic cycle.

766-11-0, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , Quality Control of 766-11-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Related Products of 1603-41-4.

Zhang, Jie;Zhang, Yufeng;Zhang, Jian;Wu, Qingguo;Yang, Haifeng research published 《 Synthesis of C3-Cyanomethylated Imidazo[1,2-a]pyridines via Ultrasound-Promoted Three-Component Reaction under Catalyst- and Oxidant-Free Conditions》, the research content is summarized as follows. An efficient synthesis of C3-cyanomethylated imidazo[1,2-a]pyridines via ultrasound-promoted three-component reaction under catalyst-free, oxidant-free, and mild conditions has been developed. A series of C3-cyanomethylated imidazo[1,2-a]pyridines were rapidly prepared with satisfactory yields and good functional group compatibility. This strategy cloud also be applied to the synthesis of zolpidem and alpidem in short steps.

1603-41-4, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, Related Products of 1603-41-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Application In Synthesis of 16133-25-8.

Zhang, Jiawei;Kong, Kaimin;Li, Xiangjun;Zhang, Qian research published 《 Kemp-type elimination of 1-arylsulfonyl-3-iodo-1H-indazoles》, the research content is summarized as follows. An intriguing ring-opening reaction of 1-arylsulfonyl-3-iodo-1H-indazoles, which can afford the corresponding ortho-(arylsulfonylamino)benzonitriles under base catalysis, was obtained unexpectedly. Herein, the optimal reaction conditions were explored and the results showed that high temperature and aprotic polar solvent are favorable to the ring-opening reaction. Most of the substrates studied can provide the corresponding ring-opening products in moderate to good yields after stirring in DMSO with K₂CO₃ at 120°C for 18 h, suggesting the excellent compatibility of functional groups and the broad substrate scope of this reaction. Furthermore, the control experiments implied that 1-arylsulfonyl-3-iodoindazoles go through an E2 elimination mechanism similar to Kemp elimination.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Application In Synthesis of 16133-25-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. HPLC of Formula: 5315-25-3.

Zhang, Hong-Tao;Su, Xiao-Jun;Xie, Fei;Liao, Rong-Zhen;Zhang, Ming-Tian research published 《 Iron-Catalyzed Water Oxidation: O-O Bond Formation via Intramolecular Oxo-Oxo Interaction》, the research content is summarized as follows. Herein, we report the importance of structure regulation on the O-O bond formation process in binuclear iron catalysts. Three complexes, [Fe₂(μ-O)(OH₂)₂(TPA)₂]⁴⁺ (1), [Fe₂(μ-O)(OH₂)₂(₆-HPA)]⁴⁺ (2) and [Fe₂(μ-O)(OH₂)₂(BPMAN)]⁴⁺ (3), have been designed as electrocatalysts for water oxidation in 0.1 M NaHCO₃ solution (pH 8.4). We found that 1 and 2 are mol. catalysts and that O-O bond formation proceeds via oxo-oxo coupling rather than by the water nucleophilic attack (WNA) pathway. In contrast, complex 3 displays negligible catalytic activity. DFT calculations suggested that the anti to syn isomerization of the two high-valent Fe=O moieties in these catalysts takes place via the axial rotation of one Fe=O unit around the Fe-O-Fe center. This is followed by the O-O bond formation via an oxo-oxo coupling pathway at the Fe^IVFe^IV state or via oxo-oxyl coupling pathway at the Fe^IVFe^V state. Importantly, the rigid BPMAN ligand in complex 3 limits the anti to syn isomerization and axial rotation of the Fe=O moiety, which accounts for the negligible catalytic activity.

HPLC of Formula: 5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem