Pyridine-derivatives

In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. For this reason, pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Safety of Pyridine-3-sulfonyl chloride.

Yu, Jiang;Zhou, Peiting;Hu, Mingxing;Yang, Liuqing;Yan, Guoyi;Xu, Ruixue;Deng, Yufang;Li, Xinghai;Chen, Yuanwei research published 《 Discovery and biological evaluation of darolutamide derivatives as inhibitors and down-regulators of wild-type AR and the mutants》, the research content is summarized as follows. Androgen receptor (AR) has been a target of prostate cancer (PC) for nearly six decades. Recently, down-regulating or degrading AR and the mutants especially the splice variant 7 (AR-V7) lacking ligand binding domain (LBD) emerged as an advantageous therapeutic approach to overcome drug resistance. Here, the structural modification of darolutamide resulted in the discovery of dual-action AR inhibitors and down-regulators. Unlike other traditional AR antagonists targeting the AR-LBD, compounds 4k and 4b not only inhibit the activities of wt-AR and AR-F876L mutant but also down-regulate the protein expression of full-length (AR-full) and AR variant 7 (AR-V7) at mRNA level. In cell proliferation assays, compounds 4k and 4b exhibited better antiproliferative activities than darolutamide and enzalutamide against AR-V7-pos. 22Rv1 cells and VCaP cells. In addition, 4k demonstrated better antitumor activity than clin. used enzalutamide in castration-resistant VCaP xenograft model. Collectively, combining the activities of AR inhibition and down-regulation, compound 4k is proposed as an advantageous lead compound to disrupt AR signaling and overcome resistance.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Safety of Pyridine-3-sulfonyl chloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. COA of Formula: C5H3BrFN.

Youn, Kyu Man;Lee, Hyuna;Yoo, Han Jong;Jung, Young Hun;Park, Jae Do;Jeong, Hyein;Lee, Jungsub;Lee, Ju Young;Kwon, Jang Hyuk research published 《 High triplet energy bipolar host materials with the combination of dibenzofuran and benziimidazobenzoimidazole moieties for blue thermally activated delayed fluorescence emitter》, the research content is summarized as follows. Two bipolar host materials were designed and synthesized for blue thermally activated delayed fluorescence (TADF) OLEDs. Both bipolar materials, 5-(4-(dibenzo[b,d]furan-2-yl)-pyridin-2-yl)-5H-benzo[d]benzo-[4,5]imidazo[1,2-a]imidazole (4-DBFBI) and 5-(5-(dibenzo[b,d]furan-2-yl)-pyridin-2-yl)-5H-benzo[d]benzo-[4,5]imidazo[1,2-a]imidazole (5-DBFBI), were constructed with a hole-transporting type of benzimidazole moiety and an electron-transporting type of dibenzofuran moiety, and these derivatives exhibit high triplet energy over 3.10 eV. To achieve a high triplet energy level, a pyridine linker was placed between the benzimidazole and dibenzofuran moieties. As a result, 4-DBFBI and 5-DBFBI showed a high triplet energy level of 3.06 eV and 2.96 eV, resp. Further, blue TADF devices were fabricated with our synthesized bipolar host materials. For our current study, we adopted 5,10-diphenyl-15-(10-(2,4,6-triisopropylphenyl)-10H-dibenzo[b,e][1,4]oxaborinin-3-yl)-10,15-dihydro-5H-diindolo[3,2-a:3′,2′-c]carbazole (PXB-DI) as the blue TADF dopant. The maximum external quantum efficiencies of the 20 wt% blue TADF devices were 31.8 and 32.5% for 4-DBFBI and 5-DBFBI, resp. Moreover, the 4-DBFBI based host device exhibited a very low efficiency roll-off of 0.93 up to 1000 cd m-2, which is attributed to its well-balanced charge transporting ability.

COA of Formula: C5H3BrFN, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , 766-11-0.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Reference of 5315-25-3.

Yoshida, Hiroto;Seki, Michinari;Kamio, Shintaro;Tanaka, Hideya;Izumi, Yuki;Li, Jialun;Osaka, Itaru;Abe, Manabu;Andoh, Hiroki;Yajima, Tomoki;Tani, Tomohiro;Tsuchimoto, Teruhisa research published 《 Direct Suzuki-Miyaura Coupling with Naphthalene-1,8-diaminato (dan)-Substituted Organoborons》, the research content is summarized as follows. The direct Suzuki-Miyaura coupling with “protected” R-B(dan) (dan = naphthalene-1,8-diaminato) (R = Ph, 4-MeOC₆H₄, 2-pyridyl) was demonstrated to smoothly occur without in situ deprotection of the B(dan) moiety. The use of KOt-Bu (Ba(OH)₂ in some cases) as a base under anhydrous conditions is the key to the successful cross-coupling, where R-B(dan) is readily converted into a transmetalation-active borate-form, regardless of the well-accepted diminished boron-Lewis acidity.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Reference of 5315-25-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. HPLC of Formula: 766-11-0.

Yoon, Sung Joon;Lee, Ho Jung;Lee, Kyung Hyung;Lee, Jun Yeob research published 《 A study on the effect of a pyridine secondary acceptor on the emission properties of thermally activated delayed fluorescence emitters》, the research content is summarized as follows. A new mol. design of thermally activated delayed fluorescence (TADF) emitters having a pyridine derived secondary acceptor was developed. Four TADF emitters were designed and synthesized to study the effect of the pyridine derived secondary acceptor on their TADF properties and device performances were studied. The 4 TADF emitters, HPy, CNPy, CF3Py and CH3Py, with a pyridine secondary acceptor decorated by functional groups were developed as an approach to manage the emission wavelength and to improve efficiency roll-off characteristics of green TADF organic light-emitting diodes by decreasing the delayed fluorescence lifetime. The pyridine secondary acceptor based TADF emitters showed short delayed fluorescence lifetimes, and the TADF emitter with the Me group functionalized pyridine secondary acceptor achieved a high external quantum efficiency (EQE) of >20% and little efficiency roll-off ≤1000 cd m^-2. Therefore, the pyridine secondary acceptor based mol. design was effective to manage the delayed fluorescence lifetime of the TADF emitters, and external quantum efficiency and efficiency roll-off of the TADF devices.

766-11-0, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , HPLC of Formula: 766-11-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Application of C6H6BrN.

Yeung, Chi-Fung;Chung, Lai-Hon;Tse, Sheung-Ying;Shek, Hau-Lam;Tse, Man-Kit;Yiu, Shek-Man;Wong, Chun-Yuen research published 《 Conventional and unconventional alkyne activations by Ru and Os for unprecedented dimetalated quinolizinium complexes》, the research content is summarized as follows. Two types of unexpected quinolizinium complexes were obtained from the reactions between pyridine-functionalized propargylic alc. HCCC(OH)(Ph)(CH₂(2-py)) (L1) and cis-[M(L-L)₂Cl₂] (M = Ru, Os; L-L = 1,1-bis(diphenylphosphino)methane (dppm), 2,2′-bipyridine (bpy)). Their mol. structures revealed that L1 can be activated by Ru and Os via the conventional vinylidene-involving or unconventional nonvinylidene-involving pathways.

Application of C6H6BrN, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., 5315-25-3.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

At 25 °C pyridine has a viscosity of 0.88 mPa/s and thermal conductivity of 0.166 W·m−1·K−1. 766-11-0, formula is C5H3BrFN, Name is 5-Bromo-2-fluoropyridine. The enthalpy of vaporization is 35.09 kJ·mol−1 at the boiling point and normal pressure.The enthalpy of fusion is 8.28 kJ·mol−1 at the melting point. Application of C5H3BrFN.

Ye, Pengqing;Shao, Yinlin;Zhang, Fangjun;Zou, Jinxuan;Ye, Xuanzeng;Chen, Jiuxi research published 《 Rare-Earth-Metal-Catalyzed Synthesis of Azaindolines and Naphthyridines via C-H Cyclization of Functionalized Pyridines》, the research content is summarized as follows. A rare-earth-metal-catalyzed insertion of a 2-pyridine C(sp²)-H bond into an intramol. unactivated vinyl bond was reported. This reaction provides streamlined access to a range of azaindolines in moderate to excellent yields. The salient features of this reaction include simple and mild reaction conditions, 100% atom efficiency, and wide substrate scope. This methodol. is also used to construct other nitrogen-containing compounds such as naphthyridine derivatives A plausible mechanism for the formation of azaindolines involving initial C-H bond activation by the lanthanide complex followed by C=C insertion into a Ln-C bond to form an alkyl lanthanide species that subsequently undergoes cyclization was proposed.

766-11-0, 5-Bromo-2-fluoropyridine is a useful research compound. Its molecular formula is C5H3BrFN and its molecular weight is 175.99 g/mol. The purity is usually 95%.
5-Bromo-2-fluoropyridine is a boronic acid that has been shown to react with iodides and form 5-bromo-2-fluoroiodobenzene. The reaction of 5-bromo-2-fluoropyridine with benzene gives the same product as the reaction with 1,3,5-trioxane. The UV absorption of 5-bromo-2-fluoropyridine is found at 230 nm and 260 nm. It also has an absorption band in the infrared region at 1625 cm−1. Vibrational progressions have been observed for this molecule, which are due to dipole moments and electron density distributions in the molecule.
5-bromo-2-fluoropyridine is used in the synthesis of heteroaromatic and aniline derivatives of piperidines as potent ligands used for vesicular acetylcholine transport. , Application of C5H3BrFN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Synthetic Route of 5315-25-3.

Yazdani, Sima;Silva, Braden E.;Cao, Thomas C.;Rheingold, Arnold L.;Grotjahn, Douglas B. research published 《 X-ray crystallography and electrochemistry reveal electronic and steric effects of phosphine and phosphite ligands in complexes Ru^II(κ⁴-bda)(PR₃)₂ and Ru^II(κ³-bda)(PR₃)₃ (bda = 2,2′-bipyridine-6,6′-dicarboxylato)》, the research content is summarized as follows. The authors have examined coordination of PR₃ = triphenylphosphine, triethylphosphine, triisopropyl phosphite, tri-Me phosphite, and 1,3,5-triaza-7-phosphaadamantane (PTA) to the fragment Ru^II(bda) to better understand how different phosphine and phosphite ligands influence the electronic and structural properties of the Ru^II complexes. PTA and P(OMe)₃ afforded complexes with three phosphorus ligands bound to Ru, with the bda being tridentate (κ³-N,N,O) in complexes 4 and 5; for the other three phosphorus ligands, even in the presence of >2 equiv, only Ru^II(κ⁴-bda)(PR₃)₂ species 1–3 were seen. Both exptl. and computational methods were used to study the complexes. Steric effects are the main factor determining whether bis- or tris(PR₃) complexes are formed. Cyclic voltammetry studies of the complexes revealed an increase in Ru^III/II potential upon having another phosphorus ligand in the equatorial position. Computational studies predict that the addnl. phosphine ligand in the equatorial plane of 4 engages in significant orbital mixing with the ruthenium center that results in lower energy bonding as compared to the axial phosphine ligands. This work provides the first evaluation of phosphorus ligand steric and electronic effects on the Ru^II(bda) fragment.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Synthetic Route of 5315-25-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Computed Properties of 1603-41-4.

Yao, Hua;Zhong, Xiaoyang;Wang, Bingqing;Lin, Sen;Yan, Zhaohua research published 《 Cyanomethylation of the Benzene Rings and Pyridine Rings via Direct Oxidative Cross-Dehydrogenative Coupling with Acetonitrile》, the research content is summarized as follows. A novel and efficient approach for the amine-directed dehydrogenative C(sp₂)-C(sp₃) coupling of arylamines RNH₂ (R = Ph, 5-chloropyridin-2-yl, pyrazin-2-yl, etc.) with acetonitrile was reported by using FeCl₂ as the catalyst. Arylamines react with inactive acetonitrile to form the corresponding arylacetonitriles R¹CH₂CN (R¹ = 2-amino-5-chloropyridin-3-yl, 2-aminophenyl, 6-amino-1,3-benzothiazol-7-yl, etc.) in moderate to good yields. This protocol features nontoxic iron catalysis, efficient atom economy, nonprefunctionalized starting materials, good regioselectivity, and excellent compatibility of functional groups and aromatic rings, providing a novel, straightforward, and green approach toward arylacetonitriles.

Computed Properties of 1603-41-4, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, 1603-41-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Category: pyridine-derivatives.

Yang, Qing;Yan, Xiao-Tong;Feng, Cheng-Tao;Chen, De-Xiang;Yan, Zhong-Zhong;Xu, Kun research published 《 Tandem Strecker/C(sp³)-H amination reactions for the construction of cyanide-functionalized imidazo[1,5-a]pyridines with NH₄SCN as a cyanating agent》, the research content is summarized as follows. An I₂O₅ promoted tandem Strecker/C(sp³)-H amination reaction of pyridine-2-carboxaldehydes, benzylamines and NH₄SCN was reported. This multicomponent reaction that allowed the single-step construction of biol. important cyano-functionalized imidazo[1,5-a]pyridines with mol. diversity was realized for the first time. Moreover, the use of safe and easy-to-handle NH₄SCN as a surrogate cyanating agent made this protocol appealing for potential applications.

Category: pyridine-derivatives, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. TThe standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Recommanded Product: Pyridine-3-sulfonyl chloride.

Yang, Chengbin;Lu, Mingzhu;Chen, Yi;Xiang, Ruiqing;Qiu, Tianze;Jia, Yu;Yang, Yongtai;Liu, Xiaofeng;Deng, Mingli;Ling, Yun;Zhou, Yaming research published 《 Development of anti-breast cancer PI3K inhibitors based on 7-azaindole derivatives through scaffold hopping: Design, synthesis and in vitro biological evaluation》, the research content is summarized as follows. Breast cancer is the cancer with the highest incidence all over the world. Phosphatidylinositol 3-kinase is an important regulator of intracellular signaling pathways, which is frequently mutated and overexpressed in majority of human breast cancers, and the inhibition of PI3K has been considered as a promising approach for the treatment of the cancer. Here, we report our design and synthesis of new 7-azaindole derivatives as PI3K inhibitors through the scaffold hopping strategy. By varying the groups at the 3-position of 7-azaindole, we identified a series of potent PI3K inhibitors, whose antiproliferative activities against two human breast cancer MCF-7 and MDA-MB-231 cell lines were evaluated. Representative derivatives FD2054 and FD2078 showed better activity than BKM120 in antiproliferation, reduced the levels of phospho-AKT and induced cell apoptosis. All these results suggested that FD2054 and FD2078 are potent PI3K inhibitors that could be considered as potential candidates for the development of anticancer agents.

16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., Recommanded Product: Pyridine-3-sulfonyl chloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem