Pyridine-derivatives

Pyridine is colorless, but older or impure samples can appear yellow. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. SDS of cas: 31181-90-5.

Yang, Chaofu;Feng, Yan;Yang, Xu;Sun, Mingxia;Li, Zhenwang;Liu, Xuan;Lu, Liang;Sun, Xianyu;Zhang, Jiwen;He, Xinhua research published 《 Synthesis and evaluation of 4-(1,3,4-oxadiazol-2-yl)-benzenesulfonamides as potent carbonic anhydrase inhibitors》, the research content is summarized as follows. Human carbonic anhydrases (hCA) I and II are targets for agents treating acute altitude sickness. Twenty-one 4-(1,3,4-oxadiazol-2-yl) benzenesulfonamides were synthesized and screened against these two isoforms. 4-(5-(2,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide , 4-(5-(2,3-dichlorophenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide, 4-(5-(4-(dimethylamino) phenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide, 4-(5-(naphthalen-2-yl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide were more potent against both hCA I and II than clin. drug AAZ. In particular, the value of compound 4-(5-(2,4-dimethylphenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide with hCA I (18.08 nM) was over 84-fold more than of AAZ with hCA I. The data of docking simulations were also in accord with the tendency of inhibitive activities. Furthermore, methanesulfonate of 4-(5-(4-(dimethylamino) phenyl)-1,3,4-oxadiazol-2-yl) benzenesulfonamide, showed better anti-hypoxia activity than AAZ in vivo, making it interesting lead compound

SDS of cas: 31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Recommanded Product: Pyridine-3-sulfonyl chloride.

Yang, Cai-Yun;Li, Xia;Liu, Bo;Huang, Guo-Li research published 《 I₂-Promoted Direct C-H Sulfenylation of Isoquinolin-1(2H)-ones with Sulfonyl Chlorides》, the research content is summarized as follows. A simple, efficient, and green method for the iodine-promoted regioselective C-4 sulfenylation of isoquinolin-1(2H)-ones using com. available aryl sulfonyl chlorides as the sulfur source was described under metal- and solvent-free conditions. The reaction proceeded smoothly under simple conditions to obtain 4-arylthioisoquinolin-1(2H)-ones, e.g. I, in moderate to good yields, and showed high regioselectivity, broad substrate scope, and good functional group tolerance. A radical reaction mechanism involving ArS^. radicals as key intermediates is proposed for the present transformation.

Recommanded Product: Pyridine-3-sulfonyl chloride, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. For this reason, pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Application of C6H4BrNO.

Yang, Bo;Yu, Shang-Bo;Zhang, Pan-Qing;Wang, Ze-Kun;Qi, Qiao-Yan;Wang, Xu-Qing;Xu, Xun-Hui;Yang, Hai-Bo;Wu, Zong-Quan;Liu, Yi;Ma, Da;Li, Zhan-Ting research published 《 Self-Assembly of a Bilayer 2D Supramolecular Organic Framework in Water》, the research content is summarized as follows. Accurate control of the layer number of orderly stacked 2D polymers has been an unsettled challenge in self-assembly. Herein we describe the fabrication of a bilayer 2D supramol. organic framework from a monolayer 2D supramol. organic framework in water by utilizing the cooperative coordination of a rod-like bipyridine ligands to zinc porphyrin subunits of the monolayer network. The monolayer supramol. framework is prepared from the co-assembly of an octacationic zinc porphyrin monomer and cucurbit[8]uril (CB[8]) in water through CB[8]-encapsulation-promoted dimerization of 4-phenylpyridiunium subunits that the zinc porphyrin monomer bear. The bilayer 2D supramol. organic framework exhibits structural regularity in both solution and the solid state, which is characterized by synchrotron small-angle X-ray scattering and high-resolution transmission electron microscopic techniques. Atomic force microscopic imaging confirms that the bilayer character of the 2D supramol. organic framework can be realized selectively on the micrometer scale.

Application of C6H4BrNO, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Related Products of 16133-25-8.

Yan, Qiuli;Cui, Wenwen;Song, Xiuyan;Xu, Guiyun;Jiang, Min;Sun, Kai;Lv, Jian;Yang, Daoshan research published 《 Sulfonylation of Aryl Halides by Visible Light/Copper Catalysis》, the research content is summarized as follows. An efficient visible-light-assisted, copper-catalyzed sulfonylation of aryl halides with sulfinates was reported. In this protocol, a single ligand CuI photocatalyst formed in-situ was used in the photocatalytic transformation. Diverse organosulfones were obtained in moderate to good yields. This strategy demonstrated a promising approach toward the synthesis of diverse and useful organosulfones.

Related Products of 16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Application of C6H4BrNO.

Yan, Qing;Qiao, Zhu;Zhao, Weizhen;Ren, Jun;Wang, Yun;Yang, Wanmei;Wang, Sheng research published 《 All-visible-light triggered solid-state dual-color fluorescence switching of phenanthroimidazole-based bisthienylethene》, the research content is summarized as follows. All-visible-light controlled fluorescence switching is more promising for bioimaging. Constructing dual-color fluorescent bisthienylethene (BTE) systems are quite challenging. Here, all-visible-light triggered dual-color fluorescence switching was achieved in a color-specific switching manner in a solid-state by associating the photochromic BTE core with a blue emissive phenanthroimidazole (PI) unit. Unique emission behavior caused by J-aggregation of the coplanar PI unit was crucial, which suggested a novel strategy for constructing dual-color fluorescent photoswitching. Moreover, a ‘turn-off’ fluorescence photoswitching was demonstrated in solution and PMMA films owing to the energy transfer from the PI moiety to a ring-closed isomer of the BTE moiety. Remarkably, an all-visible-light patterning application for information storage medium was developed with these compounds BTE-P1 was successfully utilized in cellular imaging for efficient fluorescence switching.

31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., Application of C6H4BrNO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 16133-25-8, formula is C5H4ClNO2S, Name is Pyridine-3-sulfonyl chloride. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Electric Literature of 16133-25-8.

Yan, Nicholas L.;Santos-Martins, Diogo;Nair, Reji;Chu, Alan;Wilson, Ian A.;Johnson, Kristen A.;Forli, Stefano;Morgan, Gareth J.;Petrassi, H. Michael;Kelly, Jeffery W. research published 《 Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design》, the research content is summarized as follows. In Ig light-chain (LC) amyloidosis, transient unfolding or unfolding and proteolysis enable aggregation of LC proteins, causing potentially fatal organ damage. A drug that kinetically stabilizes LCs could suppress aggregation; however, LC sequences are variable and have no natural ligands, hindering drug development efforts. We previously identified high-throughput screening hits that bind to a site at the interface between the two variable domains of the LC homodimer. We hypothesized that extending the stabilizers beyond this initially characterized binding site would improve affinity. Here, using protease sensitivity assays, we identified stabilizers that can be divided into four substructures. Some stabilizers exhibit nanomolar EC₅₀ values, a 3000-fold enhancement over the screening hits. Crystal structures reveal a key π-π stacking interaction with a conserved tyrosine residue that was not utilized by the screening hits. These data provide a foundation for developing LC stabilizers with improved binding selectivity and enhanced physicochem. properties.

Electric Literature of 16133-25-8, Pyridine-3-sulfonyl chloride is a useful research compound. Its molecular formula is C5H4ClNO2S and its molecular weight is 177.61 g/mol. The purity is usually 95%.
Pyridine-3-sulfonyl chloride is a reagent used in the synthesis of pyrimidine derivatives with anti-proliferative activity against negative breast cancer cells.
Pyridine-3-sulfonyl chloride is a chemical compound that binds to the active site of cytochrome P450 enzymes. It can be used to study the effects of matrix effect on reaction solution. Pyridine-3-sulfonyl chloride has been shown to have an UV absorption spectrum with a maximum at 280 nm and a p450 activity that is proportional to the concentration of human serum. This compound has been shown to inhibit kinase domain in vitro assays, which may have clinical relevance in the treatment of obesity., 16133-25-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Computed Properties of 1603-41-4.

Yamaguchi, Koji;Miyaguchi, Hajime;Hirakawa, Keiko;Ohno, Youkichi;Kanawaku, Yoshimasa research published 《 Qualitative analysis of zolpidem and its metabolites M-1 to M-4 in human blood and urine using liquid chromatography-tandem mass spectrometry》, the research content is summarized as follows. The aim of this study was to develop the method for the qual. anal. of zolpidem and its metabolites M-1 to M-4 using liquid chromatog.-tandem mass spectrometry (LC-MS/MS) in human blood and urine. To obtain anal. standards, a method for synthesizing zolpidem metabolites M-1 to M-4 was developed. A combination of a copper-catalyzed three-component coupling reaction and pyrrolidine-catalyzed imine formation was adopted to synthesize the Me esters of M-1 (M-1-Me) and M-2 (M-2-Me), which were hydrolyzed to afford M-1 and M-2, resp. M-3 and M-4 were also synthesized. The LC-MS/MS conditions were optimized using authentic standards M-1 to M-4 were analyzed in human blood and urine. M-1 to M-4 were successfully synthesized. The mass spectra of M-1 and M-2 were almost identical, but their peaks were chromatog. separated using a octadecyl silica column. Likewise, mass spectra of M-3 and M-4 were similar, but their peaks were chromatog. separated The peak intensities of the metabolites in human blood and urine were M-1 > M-2, and M-4 > M-3; M-3 was detected only in urine. The presence of other hydroxyzolpidems was also revealed. Chromatog. separation of M-1 and M-2 and that of M-4 and other hydroxyzolpidems is necessary to analyze zolpidem metabolites in biol. matrixes because their mass spectra are quite similar. This study is the first to analyze zolpidem and M-1 to M-4 simultaneously using LC-MS/MS, which can provide more compelling evidence of zolpidem intake.

Computed Properties of 1603-41-4, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, 1603-41-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. 1603-41-4, formula is C6H8N2, Name is 2-Amino-5-methylpyridine. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell. Name: 2-Amino-5-methylpyridine.

Yadav, Ravi Kant;Sharma, Richa;Gautam, Deepak;Joshi, Jyoti;Chaudhary, Sandeep research published 《 Lewis Acid/Oxidant as Rapid Regioselective Halogenating Reagent System for Direct Halogenation of Fused Bi-/Tri-cyclic Hetero-Aromatic Congeners viaC(sp2) -H bond Functionalization》, the research content is summarized as follows. Herein, the identification of new and fast halogenating reagent system consisting of Lewis acid AlX₃ [X=Cl, Br, I] as a halogen source in the presence of tert-Bu hydroperoxide (TBHP) which was utilized for the direct regioselective halogenation on various fused bi-/tri-cyclic hetero-aromatic congeners I [R¹ = H; R² = H, 6-Cl, 6-Me, etc.; R³ = H, 2,4-di-Cl, 4-Ph, etc.], II [R⁴ = H; R⁵ = H, 4-Cl, 3-OMe, etc.], caffeine and quinoline viaC_(sp²) -H bond functionalization was reported. The operationally simple protocol was quite fast and does not require the external halogenation source at 110°C in 20-60 min and furnished halogenated fused heterocycles I [R¹ = Cl, Br, I; R² = H, 6-Cl, 6-Me, etc.; R³ = H, 2,4-di-Cl, 4-Ph, etc.], II [R⁴ = Cl, Br, I; R⁵ = H, 4-Cl, 3-OMe, etc.], 8-chlorocaffeine, haloquinolines in up to 96% yields. The gram-scale synthesis, wide substrate scope, functional group tolerance, control experiments and application to further derivatization/functionalization for C-C bond formation further highlights the versatility of the developed methodol. as well as the compatibility of the new catalyst. The combination of Lewis acid (AlX₃) as a halogen source and TBHP (oxidant) as a halogenating reagent system was the first account for the direct regioselective halogenation of several fused bi-/tri-cyclic hetero-aromatic congenersviaC_(sp²) -H bond functionalization.

Name: 2-Amino-5-methylpyridine, 2-Amino-5-methylpyridine, also known as 2-Amino-5-methylpyridine, is a useful research compound. Its molecular formula is C6H8N2 and its molecular weight is 108.14 g/mol. The purity is usually 95%.
2-Amino-5-methylpyridine is a chemical compound that belongs to the group of methyl ketones. It has a nitrogen atom and an oxygen atom in its structure, which allows it to form hydrogen bonds with other molecules. 2-Amino-5-methylpyridine can be obtained by reacting hydrochloric acid and xanthone in the presence of a base. The compound is highly reactive and has been shown to have antiinflammatory properties. This can be attributed to its ability to inhibit prostaglandin synthesis. 2-Amino-5-methylpyridine also has fluorescence properties that are sensitive to pH changes and can be used as a probe for metal ions. 2-Amino-5-methylpyridine is an organic compound that contains a methyl group, two nitrogen atoms, and one oxygen atom in its chemical structure. This molecule can form hydrogen bonds with other molecules due to its nitrogen atoms and oxygen atom,, 1603-41-4.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine is colorless, but older or impure samples can appear yellow. 31181-90-5, formula is C6H4BrNO, Name is 5-Bromopicolinaldehyde. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Historically, pyridine was produced from coal tar. Quality Control of 31181-90-5.

Xue, Si-tu;Wang, Ya-li;Han, Xiao-wan;Yi, Hong;Jiang, Wei;Si, Shu-yi;Guo, Hui-fang;Li, Zhuo-rong research published 《 Novel cathepsin K inhibitors block osteoclasts in vitro and increase spinal bone density in zebrafish》, the research content is summarized as follows. Cathepsin K (Cat K) is a predominant cysteine protease and highly potent collagenase expressed in osteoclasts. Cat K inhibitors are anti-resorptive agents to treat osteoporosis. A novel scaffold of cathepsin K inhibitors, exemplified by lead compound 1x, was used as the template for designing and synthesizing a total of 61 derivatives that have not been reported before. An exploratory structure-activity relationship anal. identified the potent Cat K inhibitor A22, which displayed an IC₅₀ value of 0.44μM against Cat K. A22 was very specific for Cat K and caused a significantly higher in vitro inhibition of the enzyme as compared to that of lead compound 1x. A surface plasmon resonance anal. confirmed in vitro binding of A22 to Cat K. Mol. docking studies indicated several favorable interaction sites for A22 within the active pocket of Cat K. Furthermore, A22 also blocked active osteoclasts in vitro and increased spinal bone d. in zebrafish, in which it showed an activity that was higher than that of the marketed therapeutic bone metabolizer etidronate disodium. A22 represents a very promising lead compound for the development of novel antiresorptive agents functioning as orthosteric inhibitors of Cat K.

Quality Control of 31181-90-5, 5-Bromopyridine-2-carbaldehyde is a useful research compound. Its molecular formula is C6H4BrNO and its molecular weight is 186.01 g/mol. The purity is usually 95%.

5-Bromopyridine-2-carbaldehyde is a water soluble organic molecule that has been shown to inhibit the mitochondrial respiratory chain. It is a structural analog of the natural substrate for mitochondrial cytochrome c oxidase, 5-aminolevulinic acid. This compound has been shown to be selective against cancer cells and has anti-viral properties. The photophysical properties of 5-bromopyridine-2-carbaldehyde have been studied extensively. The fluorescence quantum yield of this molecule in aqueous solution is 0.06%., 31181-90-5.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pyridine has a conjugated system of six π electrons that are delocalized over the ring. 5315-25-3, formula is C6H6BrN, Name is 2-Bromo-6-methylpyridine. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Related Products of 5315-25-3.

Xu, Pengcheng;Qian, Bo;Qi, Zaojuan;Gao, Bao;Hu, Bin;Huang, Hanmin research published 《 Palladium-catalyzed dearomative cyclocarbonylation of allyl alcohol for the synthesis of quinolizinones》, the research content is summarized as follows. An approach for the synthesis of quinolizinone I (R = H, 6-Me, 7-F, etc.; R¹ = H, Me, Ph; R² = H, Me, pentyl; R³ = H, Me; X = N, CH) with potential bioactivity has been developed via palladium-catalytic dearomative cyclocarbonylation of allyl alc. R⁴C(R¹)=C(R²)CH(R³)OH (R⁴ = pyridin-2-yl, 5-fluoropyridin-2-yl, pyrazin-2-yl, etc.). Diverse quinolizinone compounds I could be attained with good efficiencies. A feasible reaction pathway could be a successive procedure of allylation, dearomatization, CO insertion and the Heck reaction.

5315-25-3, 2-Bromo-6-methylpyridine (2BMPy) is a bromopyridine derivative. It is formed when 2-chloro-6-methylpyridine is heated with bromotrimethylsilane. Its synthesis from various methods have been reported.
2-Bromo-6-methylpyridine is a building block in the preparation of nitrogen containing heterocyclic compounds.
2-Bromo-6-methylpyridine is an organic compound that belongs to the group of pyridinium halides. It is soluble in common solvents such as water, ethanol, and acetone. 2BMPy has been shown to act as a glutamate receptor antagonist and has been used in the study of glutamate receptors, including their subtypes. This chemical has also been shown to have antioxidant properties and can be used in the prevention of atherosclerosis., Related Products of 5315-25-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem