Robinett, R. Graham published the artcileThe discovery of substituted 4-(3-hydroxyanilino)-quinolines as potent RET kinase inhibitors, Computed Properties of 197958-29-5, the publication is Bioorganic & Medicinal Chemistry Letters (2007), 17(21), 5886-5893, database is CAplus and MEDLINE.
Substituted 4-(3-hydroxyanilino)-quinoline compounds, initially identified as small-mol. inhibitors of src family kinases, have been evaluated as potential inhibitors of RET kinase. Three compounds, 38, 31, and 40, had Ki‘s of 3, 25, and 50 nM in an in vitro kinase assay; while a cell based kinase assay showed Ki‘s of 300, 100, and 45 nM, resp. These compounds represent potential new leads for the treatment of medullary and papillary thyroid cancer.
Bioorganic & Medicinal Chemistry Letters published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Computed Properties of 197958-29-5.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem