Synthesis and characterization of anti-[2.2](1,6)azulenophane was written by Rudolf, Klaus;Koenig, T.. And the article was included in Tetrahedron Letters in 1985.Safety of 1-Butyl-4-methylpyridin-1-ium bromide This article mentions the following:
Two synthetic pathways afforded anti-[2.2](1,6)azulenophane (I) via fluoride induced 1,8-elimination from trimethylsilyl-tetraalkylammonium salts II (R = Me3SiCH2, R1 = Me3N+CH2.I–; R = Et2MeN+CH2.I–, R1 = Me3SiCH2). Spectral data for the title compound are also reported. In the experiment, the researchers used many compounds, for example, 1-Butyl-4-methylpyridin-1-ium bromide (cas: 65350-59-6Safety of 1-Butyl-4-methylpyridin-1-ium bromide).
1-Butyl-4-methylpyridin-1-ium bromide (cas: 65350-59-6) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Safety of 1-Butyl-4-methylpyridin-1-ium bromide