Saha, Debasmita published the artcileIntramolecular cyclization of imidazo[1,2-a]pyridines via a silver mediated/palladium catalyzed C-H activation strategy, HPLC of Formula: 1174626-28-8, the publication is Organic Chemistry Frontiers (2019), 6(13), 2234-2239, database is CAplus.
A C-H activation reaction was developed using imidazo[1,2-a]pyridine adducts via an AgOAc-mediated, Pd catalyzed intramol. cyclization for the preparation of tetrazolylpyridoimidazo[4,5-c]quinoline derivatives I (R1 = H, 9-Me, 9-Br, etc.; R2 = t-Bu, Bn, cyclohexyl, etc.). The reaction was optimized and extensively explored using the Ugi/azide MCR as a tool to rapidly broaden substrate scope. Title compounds were screened against a cancer cell panel, and I (R1 = H; R2 = 1-phenylethyl) exhibited selective, antiproliferative activity against the MCF-7 (breast cancer) cell line. This C-H activation methodol. can be utilized to rapidly reach new chem.-space for drug discovery.
Organic Chemistry Frontiers published new progress about 1174626-28-8. 1174626-28-8 belongs to pyridine-derivatives, auxiliary class Pyridine,Amine,Benzene,Ether, name is 2-Amino-6-benzyloxypyridine, and the molecular formula is C12H12N2O, HPLC of Formula: 1174626-28-8.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem