Sep-21 News A new synthetic route of 209328-55-2

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 209328-55-2, 5-Fluoropyridin-3-ol.

Reference of 209328-55-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 209328-55-2, name is 5-Fluoropyridin-3-ol. This compound has unique chemical properties. The synthetic route is as follows.

Nitric acid (0.25 mL, 5.0 mmol) was added over 1 min to a solution of 5-fluoropyridin-3-ol (0.25 g, 2.2 mmol) and sulfuric acid (3 mL) at 70 C. After 20 min, a second aliquot (0.25 mL) of nitric acid was added over 1 min. After an additional 40 min, the reaction was cooled to 0 C. Water (25 mL) was added followed by slow addition of 10 N NAOH (13 mL) at 0 C. The solution was neutralized with 1 N HCI and concentrated to give 5-FLUORO-2-NITROPYRIDIN-3-OL. MS (ESI): 158. 8 (M+H).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 209328-55-2, 5-Fluoropyridin-3-ol.

Reference:
Patent; MERCK & CO., INC.; WO2005/21529; (2005); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem