In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 70411-83-5, name is 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile, the common compound, a new synthetic route is introduced below. name: 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbonitrile
[0151] To a stirred solution of compound 11(1.67 g; 11.9 mmol; 1 eq) in methanol (80 mL) was added concentrated HC1 (1 mL) followed by 10% Pd/C (1.6 g) and the resulting mixture was stirred under hydrogen atmosphere at a pressure of 50 psi for 4 h in a Parr autoclave. The mixture was filtered through a Celite bed, washed with methanol and solvent of the filtrate was removed in vacuo to obtain the title compound (2 g, 92%). 1H NMR (DMSO-d6) oe 8.55 (brs, iH), 7.72 (d, iH, J= 7Hz), 6.46 (s, iH), 6.31 (dd, iH, J= 2,7 Hz,), 3.86 (m, 2H), 3.40 (s, 3H).
The synthetic route of 70411-83-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ASANA BIOSCIENCES, LLC; THOMPSON, Scott; VENKATESAN, Aranapakam; PRIESTLEY, Tony; KUNDU, Mrinal; SAHA, Ashis; WO2015/95128; (2015); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem