Simler, Thomas’s team published research in Organometallics in 35 | CAS: 338800-13-8

Organometallics published new progress about 338800-13-8. 338800-13-8 belongs to pyridine-derivatives, auxiliary class Bis-phosphine Ligands, name is 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, and the molecular formula is C3H9ClOS, Product Details of C23H43NP2.

Simler, Thomas published the artcilePotassium and Lithium Complexes with Monodeprotonated, Dearomatized PNP and PNCNHC Pincer-Type Ligands, Product Details of C23H43NP2, the publication is Organometallics (2016), 35(6), 903-912, database is CAplus.

The reaction of 2,6-bis(di-tert-butylphosphinomethyl)pyridine (tBuPNtBuP) with 1 molar equiv of KCH2C6H5 or LiCH2SiMe3 gave M(tBuP*NatBuP) (M = K, Li; P* = vinylic P donor, tBuP = PtBu2, Na = anionic amido N donor) after monodeprotonation of the α-lutidinyl-CH2 and concomitant dearomatization of the heterocycle. Evidence is provided that the anion tBuP*NatBuP may exist as Z- and E-isomers, interconvertible by rotation about the Cα-N-Cα-P exocyclic formal double bond. Thus, the two isomers of K(tBuP*NatBuP), i.e., [K{(Z)-(tBuP*NatBuP-κP*,κNa,κP)}(THF)], 1-Z·(THF), and [K{(E)-(tBuP*NatBuP-κNa,κP)}(THF)], 1-E·(THF), cocrystd. from THF in a 4:1 ratio. However, in the presence of DME, the isomerically pure [K{(E)-(tBuP*NatBuP-κNa,κP)}(DME)2], 1-E·2(DME), was crystallized The α-picolinyl-CH2 moiety in RPNCNHC (N = substituted 2-picoline, RP = PCy2, R = Cy; RP = PtBu2, R = tBu; CNHC = N-heterocyclic carbene) was similarly deprotonated with concomitant dearomatization using LiN(SiMe3)2. This afforded the complexes Li(RP*NaCNHC), which were crystallized as the Z- or E-isomers, [Li{(E)-(tBuP*NaCNHC-κNa,κCNHC)}(Et2O)2], 3tBu-E·2(Et2O), [Li{(Z)-(CyP*NaCNHC-κP*,κNa,κCNHC)}(Et2O)], 3Cy-Z·(Et2O), and [Li{(Z)-(tBuP*NaCNHC-κP*,κNa,κCNHC)}(Et2O)], 3tBu-Z·(Et2O). The Z- and E-isomers reversibly interconvert in solution as shown by 31P{1H} and 7Li NMR spectroscopy. The acidity of the α-picolinyl-CH2 in RPNCNHC is higher than in the known tBuPNtBuP (ca. by 6 pKa units).

Organometallics published new progress about 338800-13-8. 338800-13-8 belongs to pyridine-derivatives, auxiliary class Bis-phosphine Ligands, name is 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, and the molecular formula is C3H9ClOS, Product Details of C23H43NP2.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem