Adding a certain compound to certain chemical reactions, such as: 1190862-70-4, Ethyl 5-bromo-6-methylnicotinate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 1190862-70-4, blongs to pyridine-derivatives compound. Formula: C9H10BrNO2
2M Aqueous sodium hydroxide solution (1.91 mL, 3.8 mmol) was added to a stirred solution of ethyl 5-bromo-6-methylnicotinate (preparation 47c, 0.41 g, 1.7 mmol) in ethanol (14 mL) at room temperature. After 3 hours, the solvent was evaporated and water was added to the residue. The pH was adjusted to 4-5 with concentrated hydrochloric acid and the mixture was extracted with ethyl acetate. The organic layer was washed with water, dried (MgSO4) and evaporated to give the title compound (0.16 g, 43%) as a white solid. LRMS (m/z): 216/218 (M+1)+.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,1190862-70-4, its application will become more common.
Reference:
Patent; Laboratorios Almirall, S.A.; EP2108641; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem