Microwave-promoted syntheses of pyridine carboxamides and tert-carboximides from novel 6-acetylpyridine-2-carboxylic acid was written by Su, Biyun;Zhao, Jianshe;Zhang, Qunzheng;Qin, Wenlong. And the article was included in Synthetic Communications in 2009.Recommanded Product: 122637-39-2 This article mentions the following:
A novel 6-acetylpyridine-2-carboxylic acid was obtained during the synthesis of Et 6-acetylpyridine-2-carboxylate from 2,6-dipicolinic acid. 6-Acetylpyridine-2-carboxylic acid reaction with one or two equivalent of aromatic amines under microwave irradiation resulting in pyridine carboxamides and pyridine carboximides, resp. In the experiment, the researchers used many compounds, for example, 6-Acetylpicolinic acid (cas: 122637-39-2Recommanded Product: 122637-39-2).
6-Acetylpicolinic acid (cas: 122637-39-2) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Recommanded Product: 122637-39-2