Tag: 100-200

Synthesis and Characterization of Magnetic Functionalized Ni and Cu Nano Catalysts and Their Application in Oxidation, Oxidative Coupling and Various Multi-Component Reactions was written by Hajjami, Maryam;Sheikhaei, Shiva;Gholamian, Fatemeh;Yousofvand, Zakieh. And the article was included in Catalysis Letters in 2021.HPLC of Formula: 91-02-1 This article mentions the following:

Two magnetic nano catalysts of nickel and copper, Fe₃O₄@SiO₂@DOP-BenPyr-M(II), (M=Ni and Cu) have been synthesized. These catalysts were applied as recoverable, efficient and new heterogeneous catalysts for the high yielding and room temperature one-pot procedure of selective oxidation of sulfides to sulfoxides and oxidative coupling of thiols to disulfides. In addition, the catalytic activity of Fe₃O₄@SiO₂@DOP-BenPyr-Ni(II) was investigated as heterogeneous nanocatalyst for synthesis of 2,3-dihydroquinazolin-4(1H)-ones, 5-substituted 1H-tetrazoles and polyhydroquinolines. The synthesized catalysts were characterized by FT-IR, TGA, XRD, VSM, EDX, ICP and SEM techniques. These catalysts were recovered by an external magnet and reused several times without significant loss of catalytic efficiency. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1HPLC of Formula: 91-02-1).

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.HPLC of Formula: 91-02-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Catalytic heterocyclization of acetylenic alcohols was written by Turgunov, E.;Faizullaeva, M. F.;Sirlibaev, T. S.. And the article was included in Uzbekskii Khimicheskii Zhurnal in 1997.Name: 2-Isopropylpyridine This article mentions the following:

The reaction of some acetylenic alcs. with ammonia in the presence of oxide and fluoride-containing multicomponent catalysts, Al₂O₃/ZnO/Cr₂O₃, Al₂O₃/Cr₂O₃/ZnF₂, and Al₂O₃/ZnO/Cr₂O₃/AlF₃, has been investigated. Some derivatives of pyridine were synthesized. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Name: 2-Isopropylpyridine).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Name: 2-Isopropylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Electrochemical Reduction of Aldehydes and Ketones for the Synthesis of Alcohols and Diols under Ambient Conditions was written by Wang, Lei;Zhang, Xiao;Xia, Raymond Yang;Yang, Chao;Guo, Lin;Xia, Wujiong. And the article was included in Synlett in 2022.Category: pyridine-derivatives This article mentions the following:

A sustainable, practical, and direct strategy for the reduction of carbonyl compounds, including aldehydes and ketones, by an electrochem. pathway is presented, affording a variety of alcs. or diols as major products with decent yields. The reaction proceeds smoothly in the air at ambient temperatures with DABCO as the sacrificial reductant. Mechanistic studies revealed that direct electrochem. reduction followed by either protonation or radical-radical homocoupling is the main pathway. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1Category: pyridine-derivatives).

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of âˆ?8.7 × 10âˆ? cm3·molâˆ?.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·molâˆ? in the liquid phase and 140.4 kJ·molâˆ? in the gas phase. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Effects of Cationic Structure on Cellulose Dissolution in Ionic Liquids: A Molecular Dynamics Study was written by Zhao, Yuling;Liu, Xiaomin;Wang, Jianji;Zhang, Suojiang. And the article was included in ChemPhysChem in 2012.Recommanded Product: 125652-55-3 This article mentions the following:

In recent years, great progress has been made in the dissolution of cellulose with ionic liquids (ILs). However, the mechanism of cellulose dissolution, especially the role the IL cation played in the dissolution process, has not been clearly understood. Herein, the mixtures of cellulose with a series of imidazolium-based chloride ionic liquids and 1-butyl-3-Me pyridinium chloride ([C₄mpy]Cl) were simulated to study the effect that varying the heterocyclic structure and alkyl chain length of the IL cation has on the dissolution of cellulose. It was shown that the dissolution of cellulose in [C₄mpy]Cl is better than that in [C₄mim]Cl. For imidazolium-based ILs, the shorter the alkyl chain is, the higher the solubility will be. In addition, an all-atom force field for 1-allyl-3-Me imidazolium cation ([Amim]⁺) was developed, for the first time, to investigate the effect the electron-withdrawing group within the alkyl chain of the IL cation has on the dissolution of cellulose. It was found that the interaction energy between [Amim]⁺ and cellulose was greater than that between [C₃mim]⁺ and cellulose, indicating that the presence of electron-withdrawing group in alkyl chain of the cation enhanced the interaction between the cation and cellulose due to the increase of electronegativity of the cations. These findings are used to assess the cationic effect on the dissolution of cellulose in ILs. They are also expected to be important for rational design of novel ILs for efficient dissolution of cellulose. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3Recommanded Product: 125652-55-3).

1-Butyl-3-methylpyridinium Chloride (cas: 125652-55-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Recommanded Product: 125652-55-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Effect of structure of the catalyst and nucleophile on the efficiency of nucleophilic catalysis in S_NVin substitution reactions was written by Kravchenko, V. V.;Popov, A. F.;Kotenko, A. A.. And the article was included in Zhurnal Organicheskoi Khimii in 1992.Related Products of 644-98-4 This article mentions the following:

Rate constants for the reactions of trans-2-chlorovinyl 4-nitrophenyl sulfone with tertiary amines, e.g., trialkylamines, pyridines, imidazoles, were discussed in terms of electronic and steric factors. Depending on the catalyst and the nucleophile, general-base catalysis, nucleophilic catalysis, or nucleophilic catalysis with general-base action can be realized. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Related Products of 644-98-4).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Related Products of 644-98-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Metal-Directed Self-Assembly of {Ti₈L₂} Cluster-Based Coordination Polymers with Enhanced Photocatalytic Alcohol Oxidation Activity was written by Han, Er-Meng;Yu, Wei-Dong;Yan, Jun;Yi, Xiao-Yi;Liu, Chao. And the article was included in Inorganic Chemistry in 2022.Product Details of 91-02-1 This article mentions the following:

Cooperative assembly of the neutral cluster {Ti₈O₅(OEt)₁₈L₂} (L = pyrazine-2,3-dicarboxylic acid) with different metal units of Mn(NO₃)₂, CuCl₂, Zn(OEt)₂, Cd(NO₃)₂, Ce(NO₃)₃, Lu(NO₃)₃, and Lu(NO₃)₂(OEt), or the [Cu₂I₂] cluster, generates a family of Ti-O cluster (TOC)-based coordination polymers. These 1-dimensional (1D) linear structures contain the same {Ti₈L₂} cluster but with variable bridging metal units. The regulation of the heterometal not only affects the chain geometries of the {MTi₈} but also affects the way the 1-dimensional chains are stacked in the crystal lattice. Study of the catalytic activities toward alc. oxidation demonstrated the synergetic effect of combining the metal site and the photosensitive {Ti₈L₂} cluster in the tailored structure. Under light illumination, the {MTi₈} with dual catalytic sites shows greatly enhanced catalytic activity in the selective oxidation of alcs. to aldehydes. Because the compositions and structures of {MTi₈} are highly tunable, this work spotlights the potential of using such metal-bridged multidimensional Ti-oxo materials for cooperative photoredox catalysis for organic transformation. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1Product Details of 91-02-1).

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Product Details of 91-02-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthesis of Substituted Pyridines via Regiocontrolled [4 + 2] Cycloadditions of Oximinosulfonates was written by Renslo, Adam R.;Danheiser, Rick L.. And the article was included in Journal of Organic Chemistry in 1998.Quality Control of Methyl 3-methylpicolinate This article mentions the following:

Diels-Alder cycloadditions of 2,2-dimethyl-5-tosyloxyimino-1,3-dioxane-4,6-dione (I) with a variety of 1,3-dienes proceed with regiochem. opposite to that observed with conventional imino dienophiles, providing expeditious synthetic routes to substituted pyridines, tetrahydropyridines, and pyrrolines. I is prepared in one convenient synthetic operation from Meldrum’s acid and reacts with conjugated dienes at -78 °C in the presence of 2 equiv of dimethylaluminum chloride to afford [4 + 2] cycloadducts in good to excellent yield. Exposure of these cycloadducts to the action of NaOMe and N-chlorosuccinimide in methanol-THF at room temperature then produces substituted pyridines. The utility of this new two-step annulation protocol is demonstrated in total syntheses of the pyridine alkaloids fusaric acid and (S)-(+)-fusarinolic acid. Heating the [4 + 2] cycloadducts derived from I in a mixture of acetonitrile and pH 7 phosphate buffer induces an unusual Stieglitz-type rearrangement leading to the formation of interesting spirobicyclic pyrrolines. In the experiment, the researchers used many compounds, for example, Methyl 3-methylpicolinate (cas: 59718-84-2Quality Control of Methyl 3-methylpicolinate).

Methyl 3-methylpicolinate (cas: 59718-84-2) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Quality Control of Methyl 3-methylpicolinate

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Identification of a novel benzimidazole derivative as a highly potent NPY Y5 receptor antagonist with an anti-obesity profile was written by Tamura, Yuusuke;Hayashi, Kyouhei;Omori, Naoki;Nishiura, Yuji;Watanabe, Kana;Tanaka, Nobuyuki;Fujioka, Masahiko;Kouyama, Naoki;Yukimasa, Akira;Tanaka, Yukari;Chiba, Takeshi;Tanioka, Hideki;Nambu, Hirohide;Yukioka, Hideo;Sato, Hiroki;Okuno, Takayuki. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2013.Computed Properties of C11H9NO This article mentions the following:

Optimization of HTS hit 1 (I) for NPY Y5 receptor binding affinity, CYP450 inhibition, solubility and metabolic stability led to the identification of some orally available oxygen-linker derivatives for in vivo study. Among them, derivative 4i inhibited food intake induced by the NPY Y5 selective agonist, and chronic oral administration of 4i in DIO mice caused a dose-dependent reduction of body weight gain. In the experiment, the researchers used many compounds, for example, 5-Phenylpyridin-2-ol (cas: 76053-45-7Computed Properties of C11H9NO).

5-Phenylpyridin-2-ol (cas: 76053-45-7) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol� in pyridine vs. 150 kJ·mol� in benzene). Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Computed Properties of C11H9NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ligand Control in Selective C-H Oxidative Functionalization Using Pd-PEPPSI-Type Complexes was written by Bolbat, Ekaterina;Wendt, Ola F.. And the article was included in European Journal of Organic Chemistry in 2016.Related Products of 644-98-4 This article mentions the following:

To achieve high selectivity in directed C-H activation, an NHC ligand was introduced to a palladium catalyst. A range of Pd-PEPPSI complexes were applied in the direct acetoxylation of 2-phenylpyridine. The best catalyst is the one based on a diisopropylphenyl-substituted NHC ligand, and this was successfully used for the functionalization of sp² as well as more challenging sp³ bonds for a broad variety of substrates. The explored method showed a highly improved selectivity compared to previously reported results with up to 96% yield for the monoacetoxylated product. Kinetic studies show that sterics of the catalyst is less important in dictating conversion and selectivity; despite an induction period, the catalyst is mol. in nature. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Related Products of 644-98-4).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Related Products of 644-98-4

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Metal-Free Catalyzed Synthesis of Fluorescent Indolizine Derivatives was written by Yuan, Yu-Chang;Liu, Tian-Zhen;Zhao, Bao-Xiang. And the article was included in Journal of Organic Chemistry in 2021.Name: Phenyl(pyridin-2-yl)methanone This article mentions the following:

A mild and high efficient method to prepare indolizines such as I [R = H, Me; R¹ = Me, Ph, CH₂CH₂CO₂Et; R² = H, Me, OEt; R³ = Me, Ph, 4-ClC₆H₄; R¹R² = (CH₂)₃] by two-component reaction with the acid as the catalyst was developed. In this reaction, a new ring efficiently formed in one-step reaction. A wide range of substrates could be applied and the desired products were obtained in 8-95% yields under metal-free conditions. Different indolizine derivatives I were synthesized by general conditions and microwave irradiation conditions, and compound I [R = H, R¹ = Me, R² = H, R³ = Ph] gave the best results with an isolated yield of 95% and 82%, resp. The structures of synthesized compounds I were characterized by spectral anal., and compound I [R = H, R¹R² = (CH₂)₃, R³ = 4-ClC₆H₄] was confirmed by single crystal X-ray anal. UV-vis absorption and fluorescence properties of these compounds I were correlated with substituent groups on indolizine rings. In the experiment, the researchers used many compounds, for example, Phenyl(pyridin-2-yl)methanone (cas: 91-02-1Name: Phenyl(pyridin-2-yl)methanone).

Phenyl(pyridin-2-yl)methanone (cas: 91-02-1) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of âˆ?8.7 × 10âˆ? cm3·molâˆ?.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·molâˆ? in the liquid phase and 140.4 kJ·molâˆ? in the gas phase. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Name: Phenyl(pyridin-2-yl)methanone

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem