Tag: 100-200

Han, Ming; Liu, Yuwei; Qian, Dong-Jin; Lee, Yong-Ill; Liu, Hong-Guo published an article in 2021. The article was titled 《Large-Area Assembly of Metal-Organic Layered Ultrathin Films at the Liquid/Liquid Interface》, and you may find the article in Langmuir.Electric Literature of C12H12N2 The information in the text is summarized as follows:

Two-dimensional functional metal-organic frameworks and coordination polymers have attracted much attention and have been successfully prepared in solutions and at interfaces through the coordination of ligands to metal ions. However, the preparation of large-area ultrathin ordered films is still a challenge. Here, a modified liquid/liquid interfacial epitaxial growth method has been developed. A planar liquid/liquid interface between a chloroform solution of bipyridine derivatives and pure water was constructed first, and then an aqueous solution of Eu3+ or Cu2+ ions was added dropwise into the water phase. A layered ultrathin film with the size of several hundreds of square micrometers appeared at the liquid/liquid interface after a certain time. The monitoring results showed that the formation of ultrathin films was a result of continuous epitaxial growth of the adsorbed species due to the synergistic effects of hydrophobic effects of the alkyl chains, coordination bonds between the ligands and metal ions, π-π interactions between the ligands, and the restriction of the interface on the vertical growth. This offers a way to fabricate more large-area thin films of amphiphilic mols. In addition to this study using 4,4′-Dimethyl-2,2′-bipyridine, there are many other studies that have used 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Electric Literature of C12H12N2) was used in this study.

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.Electric Literature of C12H12N2 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Sheng, Min; Fujita, Shu; Yamaguchi, Sho; Yamasaki, Jun; Nakajima, Kiyotaka; Yamazoe, Seiji; Mizugaki, Tomoo; Mitsudome, Takato published their research in JACS Au in 2021. The article was titled 《Single-Crystal Cobalt Phosphide Nanorods as a High-Performance Catalyst for Reductive Amination of Carbonyl Compounds》.Related Products of 1122-54-9 The article contains the following contents:

Herein, the successful synthesis of single-crystal cobalt phosphide nanorods (Co2P NRs) containing coordinatively unsaturated Co-Co active sites, which serve as a new class of air-stable, highly active, and reusable heterogeneous catalysts for the reductive amination of carbonyl compounds was reported. The Co2P NR catalyst showed high activity for the transformation of a broad range of carbonyl compounds to their corresponding primary amines using an aqueous ammonia solution or ammonium acetate as a green amination reagent at 1 bar of H2 pressure; these conditions were far milder than previously reported. The air stability and high activity of the Co2P NRs was noteworthy, as conventional Co catalysts were air-sensitive (pyrophorous) and show no activity for this transformation under mild conditions. P-alloying was therefore of considerable importance for nanoengineering air-stable and highly active non-noble-metal catalysts for organic synthesis. After reading the article, we found that the author used 4-Acetylpyridine(cas: 1122-54-9Related Products of 1122-54-9)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Related Products of 1122-54-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Poly(amidoamine) Dendrimer-Coordinated Copper(II) Complexes as a Theranostic Nanoplatform for the Radiotherapy-Enhanced Magnetic Resonance Imaging and Chemotherapy of Tumors and Tumor Metastasis》 were Fan, Yu; Zhang, Jiulong; Shi, Menghan; Li, Dan; Lu, Chunhua; Cao, Xueyan; Peng, Chen; Mignani, Serge; Majoral, Jean-Pierre; Shi, Xiangyang. And the article was published in Nano Letters in 2019. Product Details of 98-98-6 The author mentioned the following in the article:

The development of a powerful nanoplatform to realize the simultaneous therapy and diagnosis of cancer using a similar element for theranostics remains a critical challenge. Herein, we report such a theranostic nanoplatform based on pyridine (Pyr)-functionalized generation 5 (G5) poly(amidoamine) dendrimers complexed with copper(II) (Cu(II)) for radiotherapy-enhanced T1-weighted magnetic resonance (MR) imaging and the synergistic radio-chemotherapy of both tumors and tumor metastasis. In this study, amine-terminated G5 dendrimers were covalently linked with 2-pyridinecarboxylic acid, acetylated to neutralize their remaining terminal amines, and complexed with Cu(II) through both the internal tertiary amines and the surface Pyr groups to form the G5.NHAc-Pyr/Cu(II) complexes. We show that the complexes are able to inhibit the proliferation of different cancer cell lines with half-maximal inhibitory concentrations ranging from 4 to 10μM and induce significant cancer cell apoptosis. Due to the presence of Cu(II), the G5.NHAc-Pyr/Cu(II) complexes display an r1 relaxivity of 0.7024 mM-1 s-1, enabling effective in vivo MR imaging of tumor xenografts and lung metastatic nodules. Further, under radiotherapy (RT) conditions, the tumor MR imaging sensitivity can be significantly enhanced, and the G5.NHAc-Pyr/Cu(II) complexes enable the enhanced chemotherapy of both a xenografted tumor model and a blood-vessel metastasis model. With the demonstrated theranostic potential of the dendrimer-Cu(II) nanocomplexes without addnl. agents or elements for RT-enhanced MR imaging and chemotherapy of tumor and tumor metastasis, this novel Cu(II)-based nanohybrids may hold great promise for the theranostics of different cancer types and metastases. After reading the article, we found that the author used Picolinic acid(cas: 98-98-6Product Details of 98-98-6)

Picolinic acid(cas: 98-98-6) is used as a chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.Product Details of 98-98-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Iridium Single-Atom Catalyst Performing a Quasi-homogeneous Hydrogenation Transformation of CO2 to Formate》 were Shao, Xianzhao; Yang, Xiaofeng; Xu, Jinming; Liu, Song; Miao, Shu; Liu, Xiaoyan; Su, Xiong; Duan, Hongmin; Huang, Yanqiang; Zhang, Tao. And the article was published in Chem in 2019. Application In Synthesis of 2,6-Diaminopyridine The author mentioned the following in the article:

Heterogeneous single-atom catalysts (SACs) with atomically dispersed active metal centers represent an intermediary between heterogeneous and homogeneous catalysis. In this work, a porous organic polymer with aminopyridine functionalities was designed to fabricate a stable, atomically dispersed Ir catalyst. This Ir-based SAC exhibits excellent catalytic activity during the liquid-phase hydrogenation of CO2 to formate. The associated turnover number is as high as 25,135, representing the best performance yet for a heterogeneous conversion of CO2 to formate. Spectral characterization and d. functional theory modeling demonstrate that the chem. structure of the Ir single-atom active site is analogous to that of a homogeneous mononuclear Ir pincer complex catalyst. As a result, a catalytic mechanism similar to that over a homogeneous Ir catalyst occurs during CO2 hydrogenation with this quasi-homogeneous Ir-based SAC. This work suggests a promising basis for the design of efficient SACs for the once-dominant homogeneous catalytic processes. In the experimental materials used by the author, we found 2,6-Diaminopyridine(cas: 141-86-6Application In Synthesis of 2,6-Diaminopyridine)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Application In Synthesis of 2,6-Diaminopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 2510-22-7In 2020 ,《Confinement Self-Assembly of Metal-Organic Cages within Mesoporous Carbon for One-Pot Sequential Reactions》 appeared in Chem. The author of the article were Zhu, Fan-Fan; Chen, Li-Jun; Chen, Shangjun; Wu, Gui-Yuan; Jiang, Wei-Ling; Shen, Ji-Chuang; Qin, Yi; Xu, Lin; Yang, Hai-Bo. The article conveys some information:

Herein, the first successful confinement self-assembly of (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO)-containing metal-organic cages within amino-functionalized mesoporous carbon to realize a new family of bifunctional heterogeneous catalyst (Cage@FDU-ED) for one-pot sequential oxidation/Knoevenagel condensation reactions of alcs. RCH2OH (R = 4-nitrophenyl, naphthalen-1-yl, cyclohexylmethyl, etc.) was presented. The orthogonal features of the isolated catalytically active sites within the obtained bifunctional catalyst lead to enhanced catalytic activities, selectivity, and recyclability with the overall transformation yielding up to 96% conversion. These results demonstrate that continuous chem. transformation with high efficiency is possible through careful design of catalytic sites in both metal-organic cages and mesoporous matrix isolatedly. This study paves a new way toward metal-organic cages as a promising platform for heterogeneous sequential reactions. In the experimental materials used by the author, we found 4-Ethynylpyridine(cas: 2510-22-7Application of 2510-22-7)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Application of 2510-22-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Dhiman, Nisha; Pradhan, Debabrata; Mohanty, Paritosh published an article in Fuel. The title of the article was 《Heteroatom (N and P) enriched nanoporous carbon as an efficient electrocatalyst for hydrazine oxidation reaction》.Category: pyridine-derivatives The author mentioned the following in the article:

An efficient heteroatom enriched electrocatalyst (HPHMC900) with high sp. surface area (SABET) of 1634 m2 g-1 was synthesized by calcination of heteroatom enriched inorganic-organic hybrid material (HPHM) with low SABET of 16 m2 g-1. A 100-fold increase in the SABET was observed in this heteroatom enriched carbon, which was used to investigate the catalytic activity for hydrazine oxidation reaction. The HPHMC900 showed low onset potential of 0.25 V vs R. H. E. The maximum c.d. of 96 mA cm-2 was achieved at 0.9 mV. The HPHMC900 performance was further compared with the parent material HPHM as well as other synthesized electrocatalysts, HPHMC500 and HPHMC700. These materials have shown onset potential of 0.5 V (HPHM), 0.48 V (HPHMC500) and 0.45 V (HPHMC700) vs R. H. E. Also, the performance of HPHMC900 was compared with the best performing com. 20% Pt/C electrocatalyst. The specimen has a min. Tafel slope of 14 mV dec-1 and 100% stability for 12 h without any loss of activity. The high SABET with exposed heteroatoms/active sites has contributed for the superior activity of HPHMC900 compared to other electrocatalysts investigated in this research. In the experimental materials used by the author, we found 2,6-Diaminopyridine(cas: 141-86-6Category: pyridine-derivatives)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Feng, Chao; Wuren, Qiqige; Zhang, Xinyu; Sun, Xiaoying; Na, Qin published their research in PLoS One in 2021. The article was titled 《Effects of dietary chromium picolinate supplementation on broiler growth performance: A meta-analysis》.Recommanded Product: Picolinic acid The article contains the following contents:

A meta-anal. was conducted to assess the effects of dietary chromium picolinate (CrPic) supplementation on broiler growth performance and to determine whether such effects are regulated by broiler strains, sex, environmental stress, or contextual factors including study area and years. Eligible studies were identified by searching the Web of Science, Springer, Elsevier, ScienceDirect, Taylor & Francis Online databases. Weighted average differences with corresponding 95% confidence intervals were computed with a random-effects model. We performed subgroup anal. stratified by study area, published years, broiler strains and sex, and environmental stress. Publication bias was assessed with Egger’s test method. A total of 15 studies eligible for inclusion. The results indicated that CrPic supplementation significantly improved broiler growth performance and subgroup anal. confirmed this conclusion. We also found that Ross 308 or male broilers might be more sensitive to CrPic supplementation and showed better growth performance. A model was used to obtain the amount of chromium addition under the optimal growth performance, which suggested that the maximum value of average daily gain (ADG) was reached when chromium addition was 1810μg/kg. The results of the sensitivity anal. showed low sensitivity and high stability of the meta-anal. CrPic supplementation had a pos. effect on the growth performance of broilers, and this meta-anal. provides a more accurate value of chromium addition, which may be beneficial for the practice of the broiler industry. After reading the article, we found that the author used Picolinic acid(cas: 98-98-6Recommanded Product: Picolinic acid)

Picolinic acid(cas: 98-98-6) is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.Recommanded Product: Picolinic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2018,Zeng, Yu; Zheng, Hao-liang; Yang, Zhao; Liu, Cheng-Kou; Fang, Zheng; Guo, Kai published 《Copper(I) Iodide-Catalyzed (Het)arylation of Diethyl Malonate with (Het)aryl Bromides by Using 1,3-Benzoxazole as a Ligand》.Synlett published the findings.Computed Properties of C5H3BrClN The information in the text is summarized as follows:

An efficient Ullmann-type coupling of aryl bromides with di-Et malonate in the presence of copper(I) iodide and 1,3-benzoxazole is presented. This method has a broad substrate scope (heterocyclic and Ph bromides) and good functional-group tolerance (OMe, Me, Ac, CN, NO2, F, and Cl). Moreover, less time is needed to reach full conversion (3-9 h). In the experiment, the researchers used many compounds, for example, 5-Bromo-2-chloropyridine(cas: 53939-30-3Computed Properties of C5H3BrClN)

5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Computed Properties of C5H3BrClN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Gui, Fukang; Jin, Qiu; Xiao, Dongdong; Xu, Xiaobin; Tan, Qinggang; Yang, Daijun; Li, Bing; Ming, Pingwen; Zhang, Cunman; Chen, Zheng; Siahrostami, Samira; Xiao, Qiangfeng published an article in Small. The title of the article was 《High-Performance Zinc-Air Batteries Based on Bifunctional Hierarchically Porous Nitrogen-Doped Carbon》.Application In Synthesis of 2,6-Diaminopyridine The author mentioned the following in the article:

Active and durable bifunctional electrocatalysts for the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) on the cathode are required for high-performance rechargeable metal-air batteries. Herein, the synthesis of hierarchically porous nitrogen-doped carbon (HPNC) with bifunctional oxygen electrocatalysis for Zn-air batteries is reported. The HPNC catalyst possesses a large surface area of 1459 m2 g-1 and exhibits superior electrocatalytic activity toward ORR and OER simultaneously with a low OER/ORR overpotential of 0.62 V, taking the difference between the potential at 10 mA cm-2 for OER and half-wave potential for ORR in 0.1 M KOH. Adopting HPNC as the air cathode, primary and rechargeable Zn-air batteries are fabricated. The primary batteries demonstrate a high open-circuit potential of 1.616 V, a specific capacity of 782.7 mAh gZn-1 and a superb peak power d. of 201 mW cm-2. The rechargeable batteries can be cycled stably for over 360 cycles or 120 h at the c.d. of 5 mA cm-2. As elucidated by d. functional theory, N-doping is preferred on defective sites with pentagon configuration and on the edge in the form of pyridinic-N-type. The high content of these two motifs in HPNC leads to the superior ORR and OER activities, resp. In the experiment, the researchers used 2,6-Diaminopyridine(cas: 141-86-6Application In Synthesis of 2,6-Diaminopyridine)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.Application In Synthesis of 2,6-Diaminopyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2022,Jia, Kai; Ma, Wenchao; Yan, Yintao; Zhang, Chenming; Jiang, Chao published an article in Synlett. The title of the article was 《A Mild and Efficient Synthesis of Pyrazolo[1,5-a]pyridines Mediated by Triphenylphosphine/Diiodine》.Application In Synthesis of 2-Bromo-5-methylpyridine The author mentioned the following in the article:

A synthesis of 2,3-diaryl-substituted pyrazolo[1,5-a]pyridines in moderate to good yields under metal-free and mild conditions was described. The intramol. cyclization of the oxime substrates was mediated by PPh3/I2, which led directly to pyrazolo[1,5-a]pyridines without the formation of a 2H-azirine intermediate. Various substituents on the aryl rings were compatible with the method.2-Bromo-5-methylpyridine(cas: 3510-66-5Application In Synthesis of 2-Bromo-5-methylpyridine) was used in this study.

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Application In Synthesis of 2-Bromo-5-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem