Tag: 100-200

Tomas, Federico M. A.; Peyrot, Analia M.; Fagalde, Florencia published their research in Polyhedron in 2021. The article was titled 《Synthesis, spectroscopic characterization and theoretical studies of polypyridine homoleptic Cu (I) complexes》.Computed Properties of C12H12N2 The article contains the following contents:

The authors focus on the synthesis and physicochem. characterization of four mononuclear copper(I) complexes with π-conjugated ligands substituted by Me groups of formulas [CuL2]+ with L = dmb, dmp, tmp and phen (dmb = 4,4′-dimethyl-2,2′-bipyridine; dmp = 5,6-dimethyl-1,10- phenanthroline; tmp = 3,4,7,8-tetramethyl-1,10-phenanthroline and phen = 1,10-phenanthroline). By TD-DFT it was possible to discuss and rationalize the geometry of the complexes and the origin of metal-to-ligand charge transfer in a square-planar distortion state. In the part of experimental materials, we found many familiar compounds, such as 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Computed Properties of C12H12N2)

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.Computed Properties of C12H12N2 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ponpao, Nipaphorn; Senapak, Warapong; Saeeng, Rungnapha; Jaratjaroonphong, Jaray; Sirion, Uthaiwan published their research in RSC Advances in 2021. The article was titled 《Metal- and solvent-free synthesis of aniline- and phenol-based triarylmethanes via Bronsted acidic ionic liquid catalyzed Friedel-Crafts reaction》.Synthetic Route of C6H4BrNO The article contains the following contents:

A beneficial, scalable and efficient methodol. for the synthesis of aniline-based triarylmethanes was established through the double Friedel-Crafts reaction of com. aldehydes and primary, secondary or tertiary anilines using Bronsted acidic ionic liquid as a powerful catalyst, namely [bsmim][NTf2] (4-sulfono-1-butylmethylimidazolium trifluoromethanesulfonimide). This protocol was successfully performed under metal- and solvent-free conditions with a broad range of substrates, giving the corresponding aniline-based triarylmethane products in good to excellent yields (up to 99%). In addition, alternative aromatic nucleophiles such as phenols and electron-rich arenes were also studied using this useful approach to achieve a diversity of triarylmethane derivatives in high to excellent yields. The results came from multiple reactions, including the reaction of 2-Bromonicotinaldehyde(cas: 128071-75-0Synthetic Route of C6H4BrNO)

2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Synthetic Route of C6H4BrNO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Aza-Henry Reaction: Synthesis of Nitronaphthylamines from 2-(Alkynyl)benzonitriles》 was written by Verma, Shalini; Kumar, Manoj; Verma, Akhilesh K.. Reference of 2-Bromonicotinaldehyde And the article was included in Organic Letters in 2020. The article conveys some information:

A transition-metal-free approach for construction of nitronaphthylamines has been developed for the first time through aza-henry, chemoselective, and regioselective annulation of 2-alkynylbenzonitriles with nitromethane. In addition, the strategy provides an elegant, operationally simple and atom-economical route for the synthesis of nitroamino substituted heterocyclic scaffolds, featuring a range of sensitive functional groups. The reaction could also devise acetonitrile and acetophenone as nucleophile. The protocol has been successfully implemented for late-stage modification of bioactive mols.2-Bromonicotinaldehyde(cas: 128071-75-0Reference of 2-Bromonicotinaldehyde) was used in this study.

2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Reference of 2-Bromonicotinaldehyde

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Synthetic Route of C7H5NIn 2019 ,《Water as a Hydrogenating Agent: Stereodivergent Pd-Catalyzed Semihydrogenation of Alkynes》 was published in Organic Letters. The article was written by Zhao, Chuan-Qi; Chen, Yue-Gang; Qiu, Hui; Wei, Lei; Fang, Ping; Mei, Tian-Sheng. The article contains the following contents:

Palladium-catalyzed transfer semihydrogenation of alkynes using H2O as the hydrogen source and Mn as the reducing reagent is developed, affording cis- and trans-alkenes selectively under mild conditions. In addition, this method provides an efficient way to access various cis-1,2-dideuterioalkenes and trans-1,2-dideuterioalkenes by using D2O instead of H2O. After reading the article, we found that the author used 4-Ethynylpyridine(cas: 2510-22-7Synthetic Route of C7H5N)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. Synthetic Route of C7H5N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Electric Literature of C6H4N2In 2022 ,《Strongly Bound π-Hole Tetrel Bonded Complexes between H2SiO and Substituted Pyridines. Influence of Substituents》 was published in ChemPhysChem. The article was written by Bhattarai, Sumitra; Sutradhar, Dipankar; Chandra, Asit K.. The article contains the following contents:

Ab initio calculation at the MP2/aug-cc-pVTZ level has been performed on the π-hole based N…Si tetrel bonded complexes between substituted pyridines and H2SiO. The primary aim of the study is to find out the effect of substitution on the strength and nature of this tetrel bond, and its similarity/difference with the N…C tetrel bond. Correlation between the strength of the N…Si bond and several mol. properties of the Lewis acid (H2SiO) and base (pyridines) are explored. The properties of the tetrel bond are analyzed using AIM, NBO, and symmetry-adapted perturbation theory calculations The complexes are characterized with short N…Si intermol. distances and high binding energies ranging between -142.72 and -115.37 kJ/mol. The high value of deformation energy indicates significant geometrical distortion of the monomer units. The AIM and NBO anal. reveal significant coordinate covalent bond character of the N…Si π-hole bond. Sharp differences are also noticed in the orbital interactions present in the N…Si and N…C tetrel bonds. In the experimental materials used by the author, we found 4-Cyanopyridine(cas: 100-48-1Electric Literature of C6H4N2)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine and pyridine-derived structures are privileged pharmacophores in medicinal chemistry and an essential functionality for organic chemists. As the prototypical π-deficient heterocycle, pyridine illustrates distinctive chemistry as both substrate and reagent. Electric Literature of C6H4N2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Recommanded Product: 1539-42-0In 2019 ,《Ruthenium(II)-Polypyridyl-Based Sensor Bearing a DPA Unit for Selective Detection of Cu(II) Ion in Aqueous Medium》 was published in ChemistrySelect. The article was written by Arora, Aayushi; Kaushal, Jolly; Kumar, Arun; Kumar, Pramod; Kumar, Sushil. The article contains the following contents:

Ruthenium(II) polypyridyl linked di-(2-picolyl)amine (DPA) based chemosensor [Ru(bpy)2(bpmpip)](PF6)2 (Ru-L) has been developed for the selective detection of Cu(II) ion in purely aqueous medium. The change in absorbance and emission spectra of chemosensor Ru-L was observable upon addition of Cu2+ ion. Competitive binding studies, detection limit (18.9 nM) and binding constants illustrate significant sensing ability of chemosensor Ru-L. Spectral behavior of chemosensor Ru-L at different pH was also investigated in absence and presence of Cu2+ ion. Binding of Cu2+ to Ru-L occurs in 1:1 stoichiometry, in good agreement with the results obatined from ESI-mass spectrometry, Job’s plot experiment and spectroscopic titrations The emission intensity of Ru-L was selectively quenched by Cu2+ ion and an obvious color change from red orange to yellow in aqueous solution as well as on paper strips was observed under UV light. The reversibility cycles for the detection of Cu2+ ion were achieved by EDTA and corresponding logic gate was also developed. The water solubility, reversibility and optical visualization of the present chemosensor make it ideal for practical applications on real samples. After reading the article, we found that the author used Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0Recommanded Product: 1539-42-0)

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry.Recommanded Product: 1539-42-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Recommanded Product: Picolinic acidIn 2020 ,《Characterization of a Mixed-Valence Ru(II)/Ru(III) Ion-Pair Complex. Unexpected High-Frequency Electron Paramagnetic Resonance Evidence for Ru(III)-Ru(III) Dimer Coupling》 was published in Inorganic Chemistry. The article was written by Impert, Olga; Kozakiewicz, Anna; Wrzeszcz, Grzegorz; Katafias, Anna; Bienko, Alina; van Eldik, Rudi; Ozarowski, Andrew. The article contains the following contents:

In this contribution, we report the synthesis and full characterization of the first mixed-valence Ru(II)/Ru(III) ion-pair complex, [RuII(bipy)2(pic)]+[cis-RuIIICl2(pic)2]-, in the solid state and in aqueous solution, where bipy = 2,2′-bipyridine and pic- = picolinate. In addition, unexpected high-frequency ESR evidence for interactions between two neighboring Ru(III) ions, resulting in a triplet state, S = 1, was found.Picolinic acid(cas: 98-98-6Recommanded Product: Picolinic acid) was used in this study.

Picolinic acid(cas: 98-98-6) is used as a chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.Recommanded Product: Picolinic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

SDS of cas: 1539-42-0In 2020 ,《A red-emitting luminescent probe for sequentially detecting Cu2+ and cysteine/histidine in aqueous solution and its imaging application in living zebrafish》 appeared in Dyes and Pigments. The author of the article were Yang, Yutong; Li, Yibin; Zhi, Xiaomin; Xu, Yingjun; Li, Minna. The article conveys some information:

A unique red-emissive luminescent probe based on dipicolyl amine (DPA) tethered ruthenium(II) tris(bipyridine) derivative (Ru-DPA) has been developed for the sequential and specific detection of Cu2+ and cysteine (Cys)/histidine (His) in pure aqueous medium. The probe Ru-DPA displayed an ′on-off′ luminescence response at 610 nm specifically toward Cu2+, accompanied by a distinct naked-eye luminescence color change from orange-red to colorless. Also, Ru-DPA enabled anal. of Cu2+ with a detection of limit as low as 0.04 μM. Addnl., the in situ generated Ru-DPA-Cu ensemble detected specifically Cys/His based on the strong affinity for Cu2+ to Cys and His, giving rise to a significant increase in the MLCT-based luminescence of Ru(II) complex and a relevant chromogenic change from colorless to orange-red. This copper (II) ion competitive-displacement detection strategy offered a good linearity with a low detection limit for Cys at 0.24 μM and His at 1.4 μM under pure aqueous medium. Moreover, Ru-DPA exhibited extremely low cytotoxicity (>90% viability at a concentration range from 20 to 100 μM), excellent membrane permeability and was successfully applied to the luminescence imaging of Cu2+ and Cys/His both in living bone mesenchymal stem cells (BMSCs) and zebrafish. The results demonstrated the great potential of Ru-DPA for monitoring Cu2+ and Cys/His in environmental and biol. systems. In the experimental materials used by the author, we found Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0SDS of cas: 1539-42-0)

Bis(pyridin-2-ylmethyl)amine(cas: 1539-42-0) is a secondary amine with two picolyl substituents. The compound is a tridentate ligand in coordination chemistry and commonly used to produce Zn-based chemosensors/probes, such as Zinpry.SDS of cas: 1539-42-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Application of 2510-22-7In 2020 ,《Synthesis and Optical Properties of Quadrupolar Pyridinium Salt and Its Application as Bioimaging Agent》 appeared in Chemistry Letters. The author of the article were Hoshi, Keita; Sanagawa, Yohei; Umebayashi, Ryuta; Tabata, Atsushi; Nagamune, Hideaki; Hase, Eiji; Minamikawa, Takeo; Yasui, Takeshi; Yoshida, Yasushi; Minagawa, Keiji; Kawamura, Yasuhiko; Imada, Yasushi; Yagishita, Fumitoshi. The article conveys some information:

We have synthesized and characterized an acceptor-π-donor-π-acceptor type pyridinium salt. The salt exhibited yellow emission with large Stokes shift in solution and was successfully excited by NIR irradiation via two-photon absorption process. In addition, it was found that the usage of the salt as a bioimaging agent for HeLa cells visualizes cell death. The combined use of the salt and a com. available green fluorescent dye for the detection of live cell viability realized the one-shot fluorescence imaging of live and dead HeLa cells under the single blue excitation. In the experiment, the researchers used many compounds, for example, 4-Ethynylpyridine(cas: 2510-22-7Application of 2510-22-7)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Application of 2510-22-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

COA of Formula: C5H7N3In 2019 ,《A new class of meta-pyridine-urea oligomers for selective identification of mercury(II) ions》 appeared in Tetrahedron Letters. The author of the article were Liu, Yajing; Chi, Chenjing; Wu, Renbo; Huang, Yong; Liu, Song; Sun, Mingyue; Sun, Yuli; Yang, Zequn; Chen, HuaLong; Wu, Zehui. The article conveys some information:

A series of new pyridine-urea oligomers were synthesized and tested for their ability to recognize ions in PBS or Ac buffer solution by fluorescence. The ability of oligourea urea to selectively recognize Hg2+ was gradually enhanced with the increase of chain, which was further proved by DFT calculation The 1:2 stoichiometry was established for the L7-Hg2+ complex on the basis of Job’s plot. The binding constant (KB) and the lowest detection limit for Hg2+ were also determined DFT calculations were used to optimize the structures of L2-7 and its Hg2+ complexes. Highly sensitive and selective probes for the recognition of Hg2+ based on this report are expected to be developed and used for in vivo detection. The results came from multiple reactions, including the reaction of 2,6-Diaminopyridine(cas: 141-86-6COA of Formula: C5H7N3)

2,6-Diaminopyridine(cas: 141-86-6) belongs to pyridine. Pyridine and its simple derivatives are stable and relatively unreactive liquids, with strong penetrating odours that are unpleasant.COA of Formula: C5H7N3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem