Tag: 100-200

Tanaka, Katsumasa; Hattori, Hiroshi; Yabe, Ryota; Nishimura, Takahiro published an article in 2022, the title of the article was Ir-Catalyzed cyclization of α,ω-dienes with an N-methyl group via two C-H activation steps.Related Products of 156267-13-9 And the article contains the following content:

Iridium-catalyzed sp3 C-H alkylation of an N-Me group with 1,5- and 1,6-dienes proceeded to give five- and six-membered carbocyclic compounds, resp., in high yields. The reaction involved intermol. alkylation of the N-Me group with a vinyl moiety and subsequent intramol. cyclization at the β-position of the initially formed alkylated intermediate. The reaction using a chiral bidentate phosphine ligand enabled the asym. synthesis of the cyclic compounds The experimental process involved the reaction of N,3-Dimethylpyridin-2-amine(cas: 156267-13-9).Related Products of 156267-13-9

The Article related to methylpyridinamine diene iridium catalyst regioselective bond activation alkylation cyclization, cycloalkylmethylpyridinamine enantioselective preparation, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Related Products of 156267-13-9

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On June 28, 2007, Glatthar, Ralf; Orain, David; Spanka, Carsten published a patent.SDS of cas: 85614-89-7 The title of the patent was Preparation of nicotinic acid derivatives as modulators of mGluR5 metabotropic glutamate receptors. And the patent contained the following:

Title compounds [I; R1 = (substituted) alkyl, PhCH2; R2 = H, (substituted) alkyl, PhCH2; R1R2N = (substituted) heterocyclyl; R3, R4 = halo, OH, alkyl, alkoxy, amino, alkylamino, dialkylamino; Q, V, W = CH, CR4, N; X = CH, N; Y = CH, CR3, N; Z = CR6aR6b, NR5, O; R5 = H, OH; R6a, R6b = H, halo, OH, amino, alkyl, alkoxy, haloalkyl; provided that Q, V, W are not all N], were prepared Thus, 6-chloro-N,N-diethylnicotinamide (preparation given) and 4-chloroaniline were heated in aqueous HOAc in a sealed vial at 100° overnight to give after chromatog. 6-(4-chlorophenylamino)-N,N-diethylnicotinamide hydrochloride. The latter at 10 μM gave 95% inhibition of mGluR5 activity. The experimental process involved the reaction of Ethyl 5-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate(cas: 85614-89-7).SDS of cas: 85614-89-7

The Article related to nicotinic acid derivative preparation mglur5 metabotropic glutamate receptor modulator, gastrointestinal nervous system urinary tract disorder treatment, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.SDS of cas: 85614-89-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On September 20, 2019, Yu, Miao; Strotman, Neil A.; Savage, Scott A.; Leung, Simon; Ramirez, Antonio published an article.Reference of Pyridine-3-sulfonic acid The title of the article was A Practical and Robust Multistep Continuous Process for Manufacturing 5-Bromo-N-(tert-butyl)pyridine-3-sulfonamide. And the article contained the following:

A multistep continuous flow process involving (1) magnesium-halogen exchange, (2) sulfonylation with sulfuryl chloride, and (3) reaction with tert-butylamine was developed for the synthesis of an arylsulfonamide pharmaceutical intermediate in the synthesis of BMS-919373. The process was successfully implemented, including a robust control strategy to manage the levels of several process impurities, to produce 76 kg of 5-bromo-N-(tert-butyl)pyridine-3-sulfonamide (I). As the instability of the reactive intermediates and existence of strong exotherms made a batch process unsuitable for production beyond a 1 kg scale, the alternative continuous process led to a practical and robust manufacturing route to the active pharmaceutical ingredient. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Reference of Pyridine-3-sulfonic acid

The Article related to bromo tertbutyl pyridine sulfonamide preparation multistep continuous process, magnesium halogen exchange sulfonylation amination continuous flow, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Reference of Pyridine-3-sulfonic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 31, 2014, Zhao, Chongjian; Li, Chuwen; Shen, Moyuan; Huang, Lanfen; Li, Qianhong; Hu, Mingyuan; Deng, Hong published an article.Electric Literature of 636-73-7 The title of the article was Syntheses, structures and photoluminescence of Cd(II) coordination polymers based on in situ synthesized bifunctional ligands. And the article contained the following:

By employing Cd(II) salt, NaN3, and CN-(CH2)n-NC (n = 1, 2) and with the absence or presence of secondary ligands, four new cadmium coordination frameworks, named, {[Cd4(btm)4(H2O)2]·3H2O}n (1); [Cd2(btm)2(H2O)]n (2); [Cd2(bte)(PMA)0.5(H2O)]n (3); and [Cd(tzp)(2,2′-bipy)]n (4) (H2btm = bis(tetrazole) methane: H2bte = 1,2-bis(tetrazole-5-yl)ethane; H2tzp = 1H-tetrazolate-5-propionic acid; bipy = bipyridine; PMA = 1,2,4,5-benzenetetracarboxylic acid) were synthesized via in situ hydrothermal reaction. Single crystal x-ray diffraction reveals that compounds 1-3 are all three-dimensional (3D) frameworks. Compound 1 is constructed by Cd1- and Cd3-btm2- layers and large bridging metalloligands. Compound 2 exhibits a 3D framework with two-dimensional (2D) Cd-btm2- (adopting μ6:κN1, N1′: κN2: κN3: κN4: κN3′: κN4’coordination mode) layers pillared by μ3:κN1, N1′: κN2: κN4′ btm2-. Compound 3 is built up by the Cd-bte2- layers and the linker PMA, with left- and right-handed helical chains arranged alternately. It is notable that btm2- takes on six different coordination modes in 1 and 2. Compound 4 represents a 2D layered framework, which can be simplified into a Shubnikov plane net (4.82̂) topol. network with 3-connected T shape linker tzp2- ligands. In addition, the research results show that compounds 1-4 exhibit different fluorescent behaviors and thermal stabilities. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Electric Literature of 636-73-7

The Article related to luminescence cadmium tetrazole coordination polymer, crystal structure cadmium tetrazole coordination polymer preparation, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Electric Literature of 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On August 31, 2002, Rice, Craig R.; Onions, Stuart; Vidal, Natalia; Wallis, John D.; Senna, Maria-Cristina; Pilkington, Melanie; Stoeckli-Evans, Helen published an article.Recommanded Product: [2,2′-Bipyridine]-3,3′-diamine The title of the article was The coordination chemistry of 3,3′-diamino-2,2′-bipyridine and its dication: Exploring the role of the amino groups by X-ray crystallography. And the article contained the following:

The synthesis and structural chem. of new divalent transition metal complexes of the bis-bidentate ligand 3,3′-diamino-2,2′-bipyridine (L1) and its dication L1H2 are described. Ligand L1 reacts with salts of divalent transition metals (Cu(II), Mn(II) and Zn) to afford the (1:1) metal-ligand complexes (2a-2d) as well as the tris complexes (3a-3f). All complexes were fully characterized by spectroscopic methods and the following compounds [Cu(L1)Cl2]2 (2a), [Cu(L1)(OAc)2] (2b), [Zn(L1)3][OTf]2 (3a), and [Zn(L1)3][ZnCl4] (3e and 3f) were structurally characterized. Results from single crystal x-ray diffraction measurements indicate that formation of an intramol. H bond between the two amino groups allows the ligand to coordinate divalent metal ions through their diimine binding sites. Also, the structure of compound 2a reveals that it crystallizes as a dimer in which each Cu ion is bound to two pyridine N atoms and two chloride ions in a distorted square planar arrangement, with a long axial contact from a neighboring amino group completing the approx. square-pyramidal geometry at CuII. Complexation of this ligand in acidic conditions afforded [Cu(L1H2)Cl4] (4), as well as the two salts [L1H2][CuCl4] (5a) and [L1H2][ZnCl4] (5b). All three compounds were structurally characterized and the dication (L1H2) displays a different coordination preference for the chelation of metal ions. In all three cases, both of the heterocyclic N atoms of the ligand are protonated, thus preventing chelation to the metal ion, although for compound 4 crystallog. studies reveal that the two amino functionalities coordinate the Cu(II) ion. The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Recommanded Product: [2,2′-Bipyridine]-3,3′-diamine

The Article related to transition metal aminobipyridine preparation structure, crystal structure transition metal aminobipyridine, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Recommanded Product: [2,2′-Bipyridine]-3,3′-diamine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On January 31, 2011, Guo, Peng; Wang, Jing; Wang, Gang; Li, Shen-jie; Huang, Wen-zhi; Lin, Yu-han; Xu, Guo-hai; Pan, Dao-cheng published an article.Safety of Pyridine-3-sulfonic acid The title of the article was Two three-dimensional pillar-layer AgI-frameworks with helical arrays containing hexamine. And the article contained the following:

Two three-dimensional pillar-layer AgI-frameworks with helical arrays were synthesized at room temperature Compound 1, {[Ag2(H2O)(L2)2L1]·H2O}n (L1 = hexamethylenetetramine, HL2 = 3-pyridinesulfonic acid), is constructed from two-dimensional (6,3) layers which are braced by helical arrays; compound 2, {[Ag3(L1)2(L3)]·6H2O}n (H3L3 = citric acid), is created by two-dimensional layers which are made up of the mix-helical arrays and further pillared by L3 anions and Ag ions. Compounds 1 and 2 were characterized by single-crystal x-ray structure determination, powder X-ray diffraction, IR and TGA. Also, the water and methanol adsorption isotherms for compound 1 were studied. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Safety of Pyridine-3-sulfonic acid

The Article related to silver hexamethylenetetramine pyridinesulfonate citrate polymeric complex preparation crystal structure, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Safety of Pyridine-3-sulfonic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On July 25, 1994, Hurh, Byungserk; Tamane, Tsuneo; Nagasawa, Toru published an article.Product Details of 636-73-7 The title of the article was Purification and characterization of nicotinic acid dehydrogenase from Pseudomonas fluorescens TN5. And the article contained the following:

Membrane-bound nicotinic acid dehydrogenase, an enzyme that catalyzes the formation of 6-hydroxynicotinic acid from nicotinic acid, was solubilized with Triton X-100, and then purified 126-fold with an 11.1% overall recovery from nicotinic acid-induced cells of Pseudomonas fluorescens TN5. The purified enzyme appeared to be homogeneous from anal. by polyacrylamide gel electrophoresis. The enzyme had a mol. mass of approx. 80 kDa and consisted of one subunit. Some electron acceptors, such as phenazine methosulfate, K3Fe(CN)6 and nitro blue tetrazolium, acted as electron acceptors. The purified enzyme catalyzed the hydroxylation of nicotinic acid to 6-hydroxynicotinic acid at a rate of 672 μmol min-1 mg-1 of protein at 35°. It also catalyzed the hydroxylation of pyrazinecarboxylic acid, 3-pyridinesulfonic acid, and 3-cyanopyridine. The purified enzyme exhibited an optimum pH of 8.3, and was sensitive to thiol reagents such as HgCl2 and p-chloromercuribenzoate. A reduction in the amount of the cytochrome c-like component in the respiratory particles was observed during the hydroxylation reaction of nicotinic acid. Thus, nicotinic acid dehydrogenase appeared to be linked to the cytochrome respiratory chain in the cells of P. fluorescens TN5. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Product Details of 636-73-7

The Article related to pseudomonas nicotinate dehydrogenase, respiratory chain coupling nicotinate dehydrogenase pseudomonas, Enzymes: Separation-Purification-General Characterization and other aspects.Product Details of 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Jia, Jing-jing; Zhang, Ling-kai; Li, Shi-xiong; Jiang, Yi-min; Pei, Luo; Yin, Xiu-ju; Liao, Bei-ling published an article in 2017, the title of the article was Synthesis, structure and magnetic analysis of the cobalt polymer based on N-[(3-pyridine)-sulfonyl]aspartate.Recommanded Product: Pyridine-3-sulfonic acid And the article contains the following content:

One new cobalt polymer [Co(L)·3H2O]n (1, H2L = N-[(3-pyridine)-sulfonyl]aspartate) has been synthesized and characterized by single-crystal x-ray diffraction and elemental anal. Polymer 1 belongs to the monoclinic system, space group P21/n with a = 11.479(2), b = 7.3180(15), c = 16.424(3) Å, β = 109.56(3) °, V = 1300.1(5) Å3, Mr = 385.22, Z = 12, F(000) = 790, S = 1.054, R = 0.0670, wR = 0.1147,(Δρ)max = 1.158 and (Δρ)min = -0.754 e/Å3. TGA showed that the polymer first lost one coordinated water mol. and then another two coordinated water mols. The values of the Curie and Curie-Weiss constants of polymer 1 are Cm = 2.67 cm3 mol-1 K and θ = -21.66 K. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Recommanded Product: Pyridine-3-sulfonic acid

The Article related to cobalt pyridinesulfonylaspartate coordination polymer preparation crystal mol structure magnetic, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Recommanded Product: Pyridine-3-sulfonic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Hurley, Nicholas J.; Rawson, Jeremy M.; Pilkington, Melanie published an article in 2015, the title of the article was 3,3′-Di(pyrazinamoyl)-2,2′-bipyridine: rational ligand design for the self-assembly of a 1-D coordination polymer.Recommanded Product: 75449-26-2 And the article contains the following content:

A new ligand, 3,3′-di(pyrazinamoyl)-2,2′-bipyridine, L3H2 was prepared and is comprised of distinct binding domains capable of facilitating the formation of coordination polymers. Reaction of L3H2 with [Cu2(OAc)4(H2O)2] in the presence of Et3N·HCl affords {[Cu3(L3)(Cl)(OAc)3]·H2O·MeOH}n (1) in which the [L3]2- anion binds two unique copper ions in a bis-tridentate fashion via amide and pyridyl N atoms. This bimetallic unit is linked to an equivalent unit via a pair of 1,3-acetato and μ-chloro bridges to afford a tetrameric [Cu4(L3)2Cl2(OAc)2] core. Coordination of one of the pyrazole substituents from each ligand to a third copper center of a rigid paddlewheel [Cu2(OAc)4] unit leads to a unique 1-dimensional polymeric structure. Magnetic studies of 1 reveal that the magnetism can be described in terms of two sets of exchange interactions; strong antiferromagnetic interactions between the two copper centers within the paddle-wheel (J/k = -190 K) and a combination of weaker ferro- and antiferro-magnetic interactions within the tetrameric core (J’/k = -5.7 K and J”/k = +2.1 K). The experimental process involved the reaction of [2,2′-Bipyridine]-3,3′-diamine(cas: 75449-26-2).Recommanded Product: 75449-26-2

The Article related to copper bipyridinebisamidopyrazine acetato complex preparation crystal structure magnetism, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Recommanded Product: 75449-26-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

On October 31, 1992, Cotton, F. Albert; Daniels, Lee M.; Murillo, Carlos A. published an article.Synthetic Route of 636-73-7 The title of the article was Synthesis and x-ray structure of two relatively air-stable chromium(II) 3-pyridinesulfonate compounds. And the article contained the following:

[Cr(pySO3)2(H2O)2]n (I; pySO3H = 3-pyridinesulfonic acid) and Cr(pySO3)2(py)4 (II) were prepared and crystal structures determined I crystallizes as monoclinic, space group P21/c in an extended structure, a 7.723(1), b 12.995(4), c 7.276(3) Å, β 100.24(2)°, Z = 2, R = 0.032, Rw = 0.046. II possesses a mol. structure and crystallizes as monoclinic, space group C2/c, a 17.084(4), b 11.031(3), c 17.828(7) Å, β 112.02(2)°, Z = 4, R = 0.031, Rw = 0.043. The coordination about the Cr atoms is, in both cases, highly distorted. Both compounds are relatively stable towards O in the solid state, especially I. The experimental process involved the reaction of Pyridine-3-sulfonic acid(cas: 636-73-7).Synthetic Route of 636-73-7

The Article related to crystal structure chromium pyridinesulfonato complex, sulfonato pyridine chromium complex, Inorganic Chemicals and Reactions: Coordination Compounds and other aspects.Synthetic Route of 636-73-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem