Tag: 100-200

Zhang, Ya-Qi; Hou, Lin; Bi, Hao-Xue; Fang, Xiao-Xue; Ma, Yuan-Yuan; Han, Zhan-Gang published an article in 2021. The article was titled 《Organic moiety-regulated Photocatalytic Performance of Phosphomolybdate hybrids for hexavalent chromium reduction》, and you may find the article in Chemistry – An Asian Journal.Formula: C12H12N2 The information in the text is summarized as follows:

Visible-light-driven photocatalytic Cr(VI) reduction is a promising pathway to moderate environmental pollution, in which the development of photocatalysts is pivotal. Herein, three hourglass-type phosphomolybdate-based hybrids with the formula of: (H2bpe)3[Zn(H2PO4)][Zn(bpe)(H2O)2]H{Zn[P4Mo6O31H6]2}·6H2O (1) Na6[H2bz]2[ZnNa4(H2O)5]{Zn [P4Mo6O31H3]2}·2H2O (2) and (H2mbpy) {[Zn(mbpy)(H2O)]2[Zn(H2O)]2}{Zn[P4Mo6O31H6]2}·10H2O (3) (bpe = trans-1,2-bi(4-pyridyl)-ethylene; bz = 4,4′-diaminobiphenyl; mbpy = 4,4′-dimethyl-2,2′bipyridine) were synthesized under the guidance of the functional organic moiety modification strategy. Structural anal. showed that hybrids 1-3 have similar 2D layer-like spatial arrangements constructed by {Zn[P4Mo6]2} clusters and organic components with different conjugated degree. With excellent redox properties and wide visible-light absorption capacities, hybrids 1-3 display favorable photocatalytic activity for Cr(VI) reduction with 79%, 70% and 64% reduction rates, which are superior to that of only inorganic {Zn[P4Mo6]2} itself (21%). The investigation of organic components on photocatalytic performance of hybrids 1-3 suggested that the organic counter cations (bpe, bz and mbpy) can effectively affect the visible-light absorption, as well as the recombination of photogenerated carriers stemmed from {Zn[P4Mo6]2} clusters, further promoting their photocatalytic performances towards Cr(VI) reduction This work provides an exptl. basis for the design of functionalized photocatalysts via the modification of organic species. In the part of experimental materials, we found many familiar compounds, such as 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Formula: C12H12N2)

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.Formula: C12H12N2 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Heydari, Somayyeh; Habibi, Davood; Reza Faraji, Ali; Keypour, Hassan; Mahmoudabadi, Masoumeh published their research in Inorganica Chimica Acta in 2021. The article was titled 《An overview on the progress and development on the palladium catalyzed direct cyanation》.Formula: C5H6BNO2 The article contains the following contents:

The simultaneous use of the new Pd nano-catalyst as well as the three types of the N-arylsulfonyl cyanamides 4-ClC6H4N(CN)S(O)2C6H4(4-X) (X = CH3, Br, NO2) as potent reagents for the in situ generation of the pos. CN ion for the direct cyanation of phenylboronic acids ArB(OH)2 [Ar = 4-ClC6H4, pyridin-3-yl, 2-(dihydroxyboranyl)phenyl, etc.] in acetonitrile at reflux conditions has been described. The experimental part of the paper was very detailed, including the reaction process of Pyridin-3-ylboronic acid(cas: 1692-25-7Formula: C5H6BNO2)

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Formula: C5H6BNO2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Heteroleptic copper(II) complexes with 2-bromo-5-methylpyridine: Structures, features of non-covalent interactions and magnetic behavior》 was written by Adonin, Sergey A.; Novikov, Alexander S.; Chernova, Katerina V.; Vinnik, Denis A.; Taskaev, Sergey V.; Korolkov, Ilya V.; Ilyina, Ekaterina V.; Pavlov, Alexander A.; Novikov, Valentin V.; Sokolov, Maxim N.; Fedin, Vladimir P.. Reference of 2-Bromo-5-methylpyridine And the article was included in Inorganica Chimica Acta in 2020. The article conveys some information:

Isostructural [Cu(2-Br-5-MePy)2X2] (2-Br-5-MePy = 2-bromo-5-methylpyridine, X = Cl 1, Br 2) were prepared and structurally characterized. Magnetic measurements reveal that both complexes demonstrate paramagnetic behavior. The results came from multiple reactions, including the reaction of 2-Bromo-5-methylpyridine(cas: 3510-66-5Reference of 2-Bromo-5-methylpyridine)

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridines form stable salts with strong acids. Pyridine itself is often used to neutralize acid formed in a reaction and as a basic solvent. Reference of 2-Bromo-5-methylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Regioisomeric monopyridine-functionalized triarylethene: small AIEgens with isomeric effect and an efficient platform for the selective and sensitive detection of Pd2+ and Fe3+》 was written by Mukherjee, Atasi; Chakravarty, Manab. Application of 1692-25-7 And the article was included in New Journal of Chemistry in 2020. The article conveys some information:

Previously, pyridine-functionalized tetraarylethenes have been established as potential AIEgens (aggregation-induced emission-active fluorogens) for numerous applications, whereas monopyridyl-linked triarylethene has been reported as a non-AIEgen. In this study, we afforded AIE-active monopyridine-functionalized unsym. substituted triarylethene in which naphthyl, biphenyl, and 4-phenylpyridine rotors were attached to an alkene stator. Moreover, two regioisomeric pyridyl compounds were synthesized to study the isomeric effect on AIE properties. Both regioisomeric compounds were found to be AIE-active with slight variation. The reasons behind the AIE properties of these compounds were substantiated by SEM studies, lifetime measurements, and mol. packing studies in a single crystal. The relatively large number of non-covalent interactions in the 4-pyridyl isomer were slightly unfavorable for the emission of fluorescence in the aggregate state; however, these interactions were beneficial for the emission of strong fluorescence in the solid state. Both compounds were individually utilized for the naked eye detection and identification of Fe3+ and Pd2+ based on the extent of fluorescence quenching in the solution state (~10-9 M detection limit) and the solid state (10-3 M for Pd2+ and 10-2 M for Fe3+). The quenching mechanism was found to involve the static and dynamic complexation of pyridyl N-atom with the metal ion. This fact was further proved by 1H NMR titration In the part of experimental materials, we found many familiar compounds, such as Pyridin-3-ylboronic acid(cas: 1692-25-7Application of 1692-25-7)

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Application of 1692-25-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Water-soluble copper(II) complexes with 4,5-dichloro-isothiazole-3-carboxylic acid and heterocyclic N-donor ligands: Synthesis, crystal structures, cytotoxicity, and DNA binding study》 was published in Inorganica Chimica Acta in 2020. These research results belong to Eremina, Julia A.; Lider, Elizaveta V.; Sukhikh, Taisiya S.; Klyushova, Lyubov S.; Perepechaeva, Maria L.; Sheven’, Dmitriy G.; Berezin, Alexey S.; Grishanova, Alevtina Y.; Potkin, Vladimir I.. Product Details of 1134-35-6 The article mentions the following:

Mixed-ligand copper(II) complexes based on 1,10-phenanthroline and related compounds are of interest to scientists due to their promising anticancer properties. In this study, four new water-soluble copper(II) complexes [Cu(dmbipy)L2], [Cu(phen)(H2O)L2], [Cu(dmphen)L2] and [Cu2(bipy)2L4], where HL – 4,5-dichloro-isothiazole-3-carboxylic acid, bipy = 2,2′-bipyridine, dmbipy = 2,2′-bi-4-picoline, phen = 1,10-phenanthroline, dmphen = 4,7-dimethyl-1,10-phenanthroline are reported. All complexes have been characterized by elemental and powder x-ray diffraction anal., EPR and IR-spectroscopy. Mol. structures of the reported complexes have been determined by single crystal x-ray diffraction. Copper(II) ion, HL and heterocyclic N-donor ligands have been found to form 1:2:1 complexes that possess square bipyramid or square pyramidal geometry. The UV-vis spectroscopy and mass spectrometry have been applied to show the behavior of the compounds in solution All complexes have been screened in vitro for their cytotoxic activity against Hep-2 and MCF-7 cell lines. They exhibit significant dose-dependent cytotoxic effect and [Cu(dmphen)L2] is the most cytotoxic (IC50 = 0.97 ± 0.03μM when compared to IC50 = 9.2 ± 0.5μM for control, cisplatin – Hep-2 cell line). The investigation of DNA binding ability by UV-vis titration technique indicates that complexes obtained exhibit moderate binding affinity toward calf thymus DNA. Effect of [Cu(dmbipy)L2] and [Cu(dmphen)L2] on activity of drug-metabolizing enzymes cytochromes P 450 has also been investigated. The addition of complexes to the hepatic microsomes of 3-MC or PB-treated rat, lead to a dose-dependent decrease of CYP’s activities. The data obtained indicate that [Cu(dmphen)L2] and [Cu(phen)(H2O)L2] can be potential anticancer agents. The experimental process involved the reaction of 4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6Product Details of 1134-35-6)

4,4′-Dimethyl-2,2′-bipyridine(cas: 1134-35-6) is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.Product Details of 1134-35-6 Furthermore, 4,4′-Dimethyl-2,2′-bipyridine is used in the synthesis of a series of o-phenanthroline-substituted ruthenium(II) complexes.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Synthesis of 2-Arylpyridines and 2-Arylbipyridines via Photoredox-Induced Meerwein Arylation with in Situ Diazotization of Anilines》 was published in Journal of Organic Chemistry in 2020. These research results belong to Hagui, Wided; Soule, Jean-Francois. Computed Properties of C7H7NO The article mentions the following:

Herein a sustainable method for the preparation of 2-arylpyridines through C-H arylation of pyridines using in situ formed diazonium salts (from com. available aromatic amines) in the presence of a photoredox catalyst under blue light-emitting diode (LED) irradiation The reaction is tolerant to a wide range of functional groups (e.g., halogen, nitrile, formyl, acetyl, ester). Applications to the C-H bond arylation of bipyridine ligands is also presented. The experimental part of the paper was very detailed, including the reaction process of 4-Acetylpyridine(cas: 1122-54-9Computed Properties of C7H7NO)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Computed Properties of C7H7NO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Copper-Catalyzed C-4 Carboxylation of 1-Naphthylamide Derivatives with CBr4/MeOH》 were Sahoo, Tapan; Sen, Chiranjit; Singh, Harshvardhan; Suresh, E.; Ghosh, Subhash Chandra. And the article was published in Advanced Synthesis & Catalysis in 2019. Recommanded Product: Picolinic acid The author mentioned the following in the article:

A copper catalyzed C-4 carboxylation reaction of 1-naphthylamide derivatives using carbon tetra bromide and methanol was reported to get corresponding ester derivatives e.g., I. Picolinamide and its derivatives were used as a bidentate directing group for the distal C4-H functionalization. Various substituted naphthylamide derivatives, and anilides were employed for the carboxylation and proceeds in good yields under mild condition. From the outcome of exptl. results, it was proposed that C4-H carboxylation reaction of 1-naphthylamides might proceed through a single electron transfer pathway. In the experimental materials used by the author, we found Picolinic acid(cas: 98-98-6Recommanded Product: Picolinic acid)

Picolinic acid(cas: 98-98-6) is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.Recommanded Product: Picolinic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《Mechanochemistry, an Easy Technique to Boost the Synthesis of CuI Pyrazine Coordination Polymers》 were Cappuccino, Chiara; Farinella, Francesco; Braga, Dario; Maini, Lucia. And the article was published in Crystal Growth & Design in 2019. SDS of cas: 100-48-1 The author mentioned the following in the article:

Depending on the exptl. conditions, the solid-state reactions of CuI with pyrazine (pyz) yield three distinct coordination polymers (CPs): a double chain polymer [Cu2I2(pyz)]n (yellow powder) and a single strand [CuI(pyz)]n (red powder) and its new isomeric compound [(CuI)2(pyz)2]n (orange powder), which present dimers of CuI bridged by the pyrazine ligands. The conversions among the three CPs were studied: by heating to 110°, [CuI(pyz)]n or [(CuI)2(pyz)2]n convert into [Cu2I2(pyz)]n, which reverts to the starting compounds upon kneading or grinding in the presence of pyrazine. The orange isomer [(CuI)2(pyz)2]n is obtained only when the solid-state reaction is performed with neat grinding or by direct melting of the pyrazine; it is unstable in the presence of solvent or vapor, and it readily transforms into the red isomer. The structure of [(CuI)2(pyz)2]n was determined by x-ray powder diffraction. [Cu2I2(pyz)]n reacts also with 4-cyanopyrazine to yield the mixed ligand compound [(CuI)(4CN-py)2 py]n, which, when heated, decomposes into [Cu2I2(pyz)]n and [(CuI)4(4CN-py)5]n. In the experiment, the researchers used 4-Cyanopyridine(cas: 100-48-1SDS of cas: 100-48-1)

4-Cyanopyridine(cas: 100-48-1) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.SDS of cas: 100-48-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Journal of Medicinal Chemistry included an article by Zhao, Chao; Huang, Dane; Li, Ruyue; Xu, Yida; Su, Shimin; Gu, Qiong; Xu, Jun. Recommanded Product: 2510-22-7. The article was titled 《Identifying Novel Anti-Osteoporosis Leads with a Chemotype-Assembly Approach》. The information in the text is summarized as follows:

In this paper, we applied a chemotype-assembly approach for ligand-based drug discovery (LBDD) to discover novel anti-osteoporosis leads. With this new approach, we identified 12 chemotypes and derived 18 major chemotype assembly rules from 245 known anti-osteoporosis compounds Then, we selected 19 compounds from an inhouse compound library using chemotype-assembly approach for anti-osteoporosis assays, which resulted in 13 hits. Based on structural features in these 13 compounds, we synthesized 50 possible anti-osteoporosis compounds from the anti-osteoporosis chemotypes by means of click chem. techniques and discovered a compound (10a, IC50 = 2 nM) with nanomolar activity. Compound 10a was then proved to be an anti-osteoporosis lead since it can prevent bone loss in vivo. After reading the article, we found that the author used 4-Ethynylpyridine(cas: 2510-22-7Recommanded Product: 2510-22-7)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Recommanded Product: 2510-22-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2018,Mikhailine, Alexandre A.; Grasa Mannino, Gabriela A.; Colacot, Thomas J. published 《Catalyst-Directed Chemoselective Double Amination of Bromo-chloro(hetero)arenes: A Synthetic Route toward Advanced Amino-aniline Intermediates》.Organic Letters published the findings.COA of Formula: C5H3BrClN The information in the text is summarized as follows:

A chemoselective sequential one-pot coupling protocol was developed for preparing several amino-anilines in high yield as building blocks for active pharmaceutical ingredients (APIs). Site (Cl vs Br on electrophile) and nucleophile (amine vs imine) selectivity is dictated by the catalyst employed. A Pd-crotyl(t-BuXPhos) precatalyst selectively coupled the Ar-Br of the polyhaloarene with benzophenone imine, even in the presence of a secondary amine, while Pd-based RuPhos or (BINAP)Pd(allyl)Cl coupled the Ar-Cl site with secondary amines. In the experimental materials used by the author, we found 5-Bromo-2-chloropyridine(cas: 53939-30-3COA of Formula: C5H3BrClN)

5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.COA of Formula: C5H3BrClN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem