Tag: 100-200

Maldonado, S.; Lopez-Vizcaino, R.; Rodrigo, M. A.; Canizares, P.; Navarro, V.; Roa, G.; Barrera, C.; Saez, C. published an article in 2021. The article was titled 《Scale-up of electrokinetic permeable reactive barriers for the removal of organochlorine herbicide from spiked soils》, and you may find the article in Journal of Hazardous Materials.Application of 98-98-6 The information in the text is summarized as follows:

This work aims to shed light on the scale-up a combined electrokinetic soil flushing process (EKSF) with permeable reactive barriers (PRB) for the treatment of soil spiked with clopyralid. To do this, remediation tests at lab (3.45 L), bench (175 L) and pilot (1400 L) scales have been carried out. The PRB selected was made of soil merged with particles of zero valent iron (ZVI) and granular activated carbon (GAC). Results show that PRB-EKSF involved electrokinetic transport and dehalogenation as the main mechanisms, while adsorption on GAC was not as relevant as initially expected. Clopyralid was not detected in the electrolyte wells and only in the pilot scale, significant amounts of clopyralid remained in the soil after 600 h of operation. Picolinic acid was the main dehalogenated product detected in the soil after treatment and mobilized by electro-osmosis, mostly to the cathodic well. The transport of volatile compounds into the atm. was promoted at pilot scale because of the larger soil surface exposed to the atm. and the elec. heating caused by ohmic losses and the larger interelectrode gap. After reading the article, we found that the author used Picolinic acid(cas: 98-98-6Application of 98-98-6)

Picolinic acid(cas: 98-98-6) is used as a chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.Application of 98-98-6

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Fujita, Shu; Yamaguchi, Sho; Yamasaki, Jun; Nakajima, Kiyotaka; Yamazoe, Seiji; Mizugaki, Tomoo; Mitsudome, Takato published an article in 2021. The article was titled 《Ni2P Nanoalloy as an Air-Stable and Versatile Hydrogenation Catalyst in Water: P-Alloying Strategy for Designing Smart Catalysts》, and you may find the article in Chemistry – A European Journal.Safety of 4-Acetylpyridine The information in the text is summarized as follows:

Non-noble metal-based hydrogenation catalysts have limited practical applications because they exhibit low activity, require harsh reaction conditions, and are unstable in air. To overcome these limitations, herein the alloying of non-noble metal nanoparticles with phosphorus as a promising strategy for developing smart catalysts that exhibit both excellent activity and air stability was proposed. A novel nickel phosphide nanoalloy (nano-Ni2P) with coordinatively unsaturated Ni active sites was synthesized. Unlike conventional air-unstable non-noble metal catalysts, nano-Ni2P retained its metallic nature in air, and exhibited a high activity for the hydrogenation of various substrates with polar functional groups, such as aldehydes, ketones, nitriles, and nitroarenes to the desired products in excellent yields in water. Furthermore, the used nano-Ni2P catalyst was easy to handle in air and could be reused without pretreatment, providing a simple and clean catalyst system for general hydrogenation reactions. In the experiment, the researchers used 4-Acetylpyridine(cas: 1122-54-9Safety of 4-Acetylpyridine)

4-Acetylpyridine(cas: 1122-54-9) belongs to pyridine. When pyridine is adsorbed on oxide surfaces or in porous materials, the following species are commonly observed: (i) pyridine coordinated to Lewis acid sites, (ii) pyridine H-bonded to weakly acidic hydroxyls, and (iii) protonated pyridine. At high coverage, physisorbed pyridine and protonated dimers can also be observed.Safety of 4-Acetylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Qin, Su; Lei, Yang; Guo, Jing; Huang, Jian-Feng; Hou, Chao-Ping; Liu, Jun-Min published an article in 2021. The article was titled 《Constructing Heterogeneous Direct Z-Scheme Photocatalysts Based on Metal-Organic Cages and Graphitic-C3N4 for High-Efficiency Photocatalytic Water Splitting》, and you may find the article in ACS Applied Materials & Interfaces.Electric Literature of C5H6BNO2 The information in the text is summarized as follows:

The development of artificial devices that mimic the highly efficient and ingenious photosystems in nature is worthy of in-depth study. A metal-organic cage (MOC) Pd2(M-4)4(BF4)4, denoted as MOC-Q1, integrating four organic photosensitized ligands M-4 and two Pd2+ catalytic centers is designed for a photochem. mol. device (PMD). MOC-Q1 is successfully immobilized on graphitic carbon nitride (g-C3N4) by hydrogen bonds to obtain a robust heterogeneous direct Z-scheme g-C3N4/MOC-Q1 photocatalyst for H2 generation under visible light. The optimized g-C3N4/MOC-Q1 (2 wt %) system shows high hydrogen evolution activity (4495 μmol g-1 h-1 based on the catalyst mass) and exhibits stable performances for 25 h (a turnover number of 19,268 based on MOC-Q1), significantly outperforming pure MOC-Q1, g-C3N4, and comparsion materials Pd/g-C3N4/M-4, which is the highest one of all reported heterogeneous MOC-based photocatalysts under visible irradiation This enhancement can be ascribed to the synergistic effects of high-efficient electron transfer, extended visible-light response region, and good protective environment for MOC-Q1 arising from an efficient direct Z-scheme heterostructure of g-C3N4/MOC-Q1. This rationally designed and synthesized MOC/g-C3N4-based heterogeneous PMD is expected to have great potential in photocatalytic water splitting. In the experiment, the researchers used many compounds, for example, Pyridin-3-ylboronic acid(cas: 1692-25-7Electric Literature of C5H6BNO2)

Pyridin-3-ylboronic acid(cas: 1692-25-7) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Electric Literature of C5H6BNO2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Lauzon, Samuel; Caron, Laurent; Ollevier, Thierry published their research in Organic Chemistry Frontiers in 2021. The article was titled 《Efficient stereoselective synthesis of chiral 3,3′-dimethyl-(2,2′-bipyridine)-diol ligand and applications in FeII-catalysis》.COA of Formula: C6H6BrN The article contains the following contents:

A seven step synthesis of a chiral 2,2′-bipyridinediol ligand with 3,3′-dimethyl substituents was achieved starting from com. available materials. The O2-mediated oxidative homocoupling reaction of a chiral pyridine N-oxide was demonstrated to be the key step to prepare the S,S enantiomer of the title ligand with excellent stereoselectivities, i.e., 99% de and >99.5% ee. An unusual heptacoordination of FeII when complexed with the chiral 2,2′-bipyridinediol ligand was highlighted from single crystal diffraction anal. Steric strain due to the 3,3′-dimethyl groups was revealed from the structural anal. of the obtained FeII complex. Asym. induction using this chiral 3,3′-dimethyl-(2,2′-bipyridine)-diol ligand was studied in the Mukaiyama aldol and thia-Michael reactions. An increase of chiral induction in the latter one was achieved using the FeII catalyst made from newly synthesized ligand vs. Bolm’s ligand. After reading the article, we found that the author used 2-Bromo-5-methylpyridine(cas: 3510-66-5COA of Formula: C6H6BrN)

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. COA of Formula: C6H6BrN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Nickel-Catalyzed Sonogashira C(sp)-C(sp2) Coupling through Visible-Light Sensitization》 was written by Zhu, Da-Liang; Xu, Ruijie; Wu, Qi; Li, Hai-Yan; Lang, Jian-Ping; Li, Hong-Xi. SDS of cas: 2510-22-7 And the article was included in Journal of Organic Chemistry in 2020. The article conveys some information:

An efficient method for visible-light-initiated, nickel-catalyzed Sonogashira C(sp)-C(sp2) coupling has been developed via an energy-transfer mode. Thioxanthen-9-one as a photosensitizer could significantly accelerate the arylation of alkynes with a wide range of (hetero)aryl halides in high yields. The cross-coupling reaction undergoes the stepwise oxidative addition of an arylhalide to nickel(0), transmetalation of the resulting aryl-Ni(II) halide species with Zn(II) acetylide into aryl-Ni(II) acetylide species, energy transfer from the excited state of thioxanthen-9-one to aryl-Ni(II) acetylide, and reductive elimination to the aryl alkyne. The experimental process involved the reaction of 4-Ethynylpyridine(cas: 2510-22-7SDS of cas: 2510-22-7)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridine derivatives lend themselves to many roles in the spirited field of supramolecular chemistry – whether as the ligand backbone of metal-organic polymers or presiding over the key electronic stations of nanodevices. In biochemistry, pyridine-containing cofactors are necessary nutrients on which our lives depend. SDS of cas: 2510-22-7

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy》 was published in Brain, Behavior, and Immunity in 2020. These research results belong to Ryan, Karen M.; Allers, Kelly A.; McLoughlin, Declan M.; Harkin, Andrew. Recommanded Product: Picolinic acid The article mentions the following:

Tryptophan and kynurenine pathway (KP) metabolites are implicated in the pathophysiol. of depression. We aimed to investigate their plasma concentrations in medicated patients with depression (n = 94) compared to age- and sex-matched healthy controls (n = 57), and in patients with depression after electroconvulsive therapy (ECT) in a real-world clin. setting, taking account of co-variables including ECT modality and heterogenous psychopathol. Depression severity was assessed using the Hamilton Depression Rating Scale (HAM-D24). Tryptophan (TRP) and kynurenine (KYN) metabolite concentrations [anthranilic acid (AA), 3-hydroxyanthranilic acid (3HAA), picolinic acid (PA), kynurenic acid (KYNA), and xanthurenic acid (XA)] and KYNA/KYN and KYNA/quinolinic acid (QUIN) ratios were lower in patients compared to controls. For the total group there was no significant change in KP metabolites post-ECT or correlations with mood ratings. However, improvements in mood score were correlated with increased KYN, 3-hydroxykynurenine (3HK), 3HAA, QUIN, and KYN/TRP in a subgroup of unipolar depressed patients. Addnl., in remitters baseline KYN, 3HK, and QUIN were associated with baseline HAM-D24 scores, and changes in 3HK and 3HAA concentrations post-ECT correlated with improvement in mood. KYN, KYNA, AA, 3HK, XA, PA, and QUIN were increased in a smaller 3-mo follow-up group (n = 19) compared to pre-ECT concentrations Overall, the results indicate that ECT mobilizes the KP, where a moderate association between selected metabolites and treatment response in unipolar depressed patients is evident. In the experiment, the researchers used Picolinic acid(cas: 98-98-6Recommanded Product: Picolinic acid)

Picolinic acid(cas: 98-98-6) is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.Recommanded Product: Picolinic acid

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Asymmetric Synthesis of Multifunctionalized 2,3-Benzodiazepines by a One-pot N-Heterocyclic Carbene/Chiral Palladium Sequential Catalysis》 was published in Journal of Organic Chemistry in 2020. These research results belong to Ding, Ya-Li; Zhao, Yun-Long; Niu, Shuang-Shuo; Wu, Pei; Cheng, Ying. Computed Properties of C6H4BrNO The article mentions the following:

The first example of the construction of chiral 2,3-benzodiazepine compounds which are of biol. and pharmaceutical relevance by asym. catalysis is reported. Catalyzed by a thiazolium derived carbene and a palladium-chiral bidentate phosphine complex in sequence, one-pot reaction between 1-(2-(2-nitrovinyl)aryl)allyl esters with azodicarboxylates took place efficiently at ambient temperature to produce 4-nitro-1-vinyl-1H-2,3-benzodiazepine-2,3-dicarboxylates I (R = Me, Et, iPr; Z = C, N; X, Y = H, Me, Cl, etc.) in good to excellent yields with an enantiomeric ratio up to 95 : 5. In the part of experimental materials, we found many familiar compounds, such as 2-Bromonicotinaldehyde(cas: 128071-75-0Computed Properties of C6H4BrNO)

2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Computed Properties of C6H4BrNO

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Iridium(III)-Catalyzed Tandem Annulation of Pyridine-Substituted Anilines and α-Cl Ketones for Obtaining 2-Arylindoles》 was published in Journal of Organic Chemistry in 2020. These research results belong to Cui, Xin-Feng; Qiao, Xin; Wang, He-Song; Huang, Guo-Sheng. Recommanded Product: 3510-66-5 The article mentions the following:

A facile and expeditious protocol for the synthesis of 2-arylindole compounds from readily available N-(2-pyridyl)anilines and com. available α-Cl ketones through iridium-catalyzed C-H activation and cyclization is reported here. As a complementary approach to the conventional strategies for indole synthesis, the transformation exhibits powerful reactivity, tolerates a large number of functional groups, and proceeds with good to excellent yields under mild conditions, providing a straightforward method to obtain structurally diverse and valuable indole scaffolds. Furthermore, the reaction could be easily scaled up to gram scale. In the part of experimental materials, we found many familiar compounds, such as 2-Bromo-5-methylpyridine(cas: 3510-66-5Recommanded Product: 3510-66-5)

2-Bromo-5-methylpyridine(cas: 3510-66-5) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Recommanded Product: 3510-66-5

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Journal of Organic Chemistry included an article by Zhang, Yu-Fang; Duan, Wen-Di; Chen, Jingjing; Hu, Youhong. Safety of 4-Ethynylpyridine. The article was titled 《Base-Promoted Cascade Reactions of 3-(1-Alkynyl)chromones with Pyridinium Ylides to Chromeno[2,3-d]azepine Derivatives》. The information in the text is summarized as follows:

A base-promoted cascade reaction of 3-(1-alkynyl)chromones with pyridinium ylides has been developed to afford a novel chromeno[2,3-d]azepine scaffold in an efficient and economic manner. This tandem process involves multiple reactions including a Michael addition/deprotonation/alkyne-allene isomerization/cyclization and the subsequent 1,2-addition under mild conditions without a transition metal catalyst. In the part of experimental materials, we found many familiar compounds, such as 4-Ethynylpyridine(cas: 2510-22-7Safety of 4-Ethynylpyridine)

4-Ethynylpyridine(cas: 2510-22-7) belongs to pyridine. Pyridines are often used as catalysts or reagents; particular notice has been paid recently to how pyridine coordinates to metal centers enabling a wide range of valuable reactions. Safety of 4-Ethynylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2019,Bioorganic Chemistry included an article by Benchekroun, Mohamed; Pachon-Angona, Irene; Luzet, Vincent; Martin, Helene; Oset-Gasque, Maria-Jesus; Marco-Contelles, Jose; Ismaili, Lhassane. SDS of cas: 128071-75-0. The article was titled 《Synthesis, antioxidant and Aβ anti-aggregation properties of new ferulic, caffeic and lipoic acid derivatives obtained by the Ugi four-component reaction》. The information in the text is summarized as follows:

We report herein the synthesis antioxidant and Aβ anti-aggregation capacity of (E)-N-benzyl-N-[2-(benzylamino)-2-oxoethyl]-3-(aryl)acrylamides and related (R)-N-benzyl-N-(2-(benzylamino)-2-oxoethyl)-5-(1,2-dithiolan-3-yl)pentanamides 1-12. These compounds have been obtained, via Ugi four-component reaction, from modest to good yields. Their antioxidant anal., using the DPPH and ORAC assays, allowed us to identify compounds 8 and 9, as potent antioxidant agents, showing also strong Aβ1-40 self-aggregation inhibition, two biol. properties of interest in pathologies linked to the oxidative stress, such as Alzheimer’s disease. In the experimental materials used by the author, we found 2-Bromonicotinaldehyde(cas: 128071-75-0SDS of cas: 128071-75-0)

2-Bromonicotinaldehyde(cas: 128071-75-0) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.SDS of cas: 128071-75-0

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem