Tag: 100-200

Lanthanide (III) complexes of 3-(ethylthio)phenyl-substituted phthalocyanines: Synthesis and physicochemical properties was written by Dubinina, Tatiana V.;Tychinsky, Pavel I.;Borisova, Nataliya E.;Krasovskii, Vitaly I.;Ivanov, Anton S.;Savilov, Serguei V.;Maklakov, Sergey S.;Sedova, Marina V.;Tomilova, Larisa G.. And the article was included in Dyes and Pigments in 2018.Name: Pyridinehydrochloride This article mentions the following:

Novel phthalocyaninates of terbium, erbium and lutetium, bearing 3-(ethylthio)phenyl peripheral groups, were synthesized with high yields. The complexes obtained were characterized by ¹H NMR spectroscopy, FTIR spectroscopy and high-resolution mass spectrometry. Thermal stability of the lanthanide complexes was examined using TGA combined with FTIR spectroscopy. Strong upfield (up to -59.06) and downfield (up to 22.32) lanthanide-induced shifts of signals of aromatic protons were observed in NMR spectra of terbium and erbium complexes, resp. It was shown, that comparing to phenyl-substituted analogs the introduction of ethylthio-moieties in the meta-positions of Ph substituents does not affect the Q band maxima. Hybrid gold nanoparticles coated with mols. of the lutetium complex were obtained and their optical properties were studied. The formation of phthalocyanine shell and its composition were proven using at. force and TEM. Absorption cross sections of ground and the first excited states were calculated using the data of open-aperture z-scan measurements for lutetium complex and hybrid gold nanoparticles on its basis. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Name: Pyridinehydrochloride).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Name: Pyridinehydrochloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Selective synthesis of 2-substituted pyridine N-oxides via directed ortho-metalation using Grignard reagents was written by Andersson, Hans;Gustafsson, Magnus;Olsson, Roger;Almqvist, Fredrik. And the article was included in Tetrahedron Letters in 2008.Product Details of 3718-65-8 This article mentions the following:

Addition of i-PrMgCl to pyridine N-oxides in THF at -78 °C generates selectively an ortho-metalated species, which can be trapped with various electrophiles to generate 2-substituted pyridine N-oxides. Furthermore, by applying a double metal-catalyzed cross-coupling, direct arylation of the pyridine N-oxides is achieved. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Product Details of 3718-65-8).

3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Product Details of 3718-65-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Catalytic Asymmetric Hydroalkylation of α,β-Unsaturated Amides Enabled by Regio-Reversed and Enantiodifferentiating syn-Hydronickellation was written by Zhou, Fang;Zhu, Shaolin. And the article was included in ACS Catalysis in 2021.SDS of cas: 24103-75-1 This article mentions the following:

Here, an enantioselective nickel-hydride catalyzed hydroalkylation of readily accessible β-alkyl-α,β-unsaturated amides to form structurally diverse β-chiral amides e.g., I was reported. This process was proposed to proceed through an enantiodifferentiating syn-hydrometalation of nickel hydride, forming chiral alkylnickel at β-position in which regioselectivity is different than that with copper hydride. This regio-reversed hydronickellation process provided a complementary approach to access enantioenriched β-functionalization amides with a stereocenter at β-position. In the experiment, the researchers used many compounds, for example, 4-Methoxy-2-methylpyridine (cas: 24103-75-1SDS of cas: 24103-75-1).

4-Methoxy-2-methylpyridine (cas: 24103-75-1) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. SDS of cas: 24103-75-1

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Organic Semiconducting Polymer Nanoparticles for Photoacoustic Labeling and Tracking of Stem Cells in the Second Near-Infrared Window was written by Yin, Chao;Wen, Guohua;Liu, Chao;Yang, Boguang;Lin, Sien;Huang, Jiawei;Zhao, Pengchao;Wong, Siu Hong Dexter;Zhang, Kunyu;Chen, Xiaoyu;Li, Gang;Jiang, Xiaohua;Huang, Jianping;Pu, Kanyi;Wang, Lidai;Bian, Liming. And the article was included in ACS Nano in 2018.Electric Literature of C5H6ClN This article mentions the following:

Photoacoustic (PA) imaging and tracking of stem cells plays an important role in the real-time assessment of cell-based therapies. Nevertheless, the limitations of conventional inorganic PA contrast agents and the narrow range of the excitation wavelength in the first near-IR (NIR-I) window hamper the applications of PA imaging in living subjects. Herein, we report the design and synthesis of a second near-IR (NIR-II) absorptive organic semiconducting polymer (OSP)-based nanoprobe (OSPN⁺) for PA imaging and tracking of stem cells. Comparison studies in biol. tissue show that NIR-II light excited PA imaging of the OSPN⁺ has significantly higher signal-to-noise ratio than NIR-I light excited PA imaging, thereby demonstrating the superiority of the OSPN⁺ for deep tissue imaging. With good biocompatibility, appropriate size, and optimized surface property, the OSPN⁺ shows enhanced cellular uptake for highly efficient PA labeling of stem cells. In vivo investigations reveal significant NIR-II PA contrast enhancement of the transplanted OSPN⁺-labeled human mesenchymal stem cells by 40.6- and 21.7-fold in s.c. and brain imaging, resp., compared with unlabeled cases. Our work demonstrates a class of OSP-based nanomaterials for NIR-II PA stem cell imaging to facilitate a better understanding and evaluation of stem cell-based therapies. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Electric Literature of C5H6ClN).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Electric Literature of C5H6ClN

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mn^II-based MIL-53 Analogues: Synthesis Using Neutral Bridging μ₂-Ligands and Application in Liquid-Phase Adsorption and Separation of C6-C8 Aromatics was written by Xu, Guohai;Zhang, Xiaoguang;Guo, Peng;Pan, Chengling;Zhang, Hongjie;Wang, Cheng. And the article was included in Journal of the American Chemical Society in 2010.Category: pyridine-derivatives This article mentions the following:

Four Mn^II-based MIL-53 single crystals were prepared using four neutral pyridine N-oxides as bridging μ₂-ligands. In the case of 4,4′-bipyridine-N,N’-dioxide (BPNO), the infinite Mn oxide chains were further interconnected by BPNO besides BDC, which allows 1-dimensional channels to be accessible for guest mols. The liquid-phase adsorption and separation of C6-C8 aromatics using the evacuated compound as an absorbent were studied via crystal-to-crystal transformations. Both structural evolution of the compounds and selectivity of C6-C7 aromatics of one evacuated compound could be attributed to noncovalent interactions, especially π-π interaction. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Category: pyridine-derivatives).

3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Nitrogenase-mimic iron-containing chalcogels for photochemical reduction of dinitrogen to ammonia was written by Liu, Jian;Kelley, Matthew S.;Wu, Weiqiang;Banerjee, Abhishek;Douvalis, Alexios P.;Wu, Jinsong;Zhang, Yongbo;Schatz, George C.;Kanatzidis, Mercouri G.. And the article was included in Proceedings of the National Academy of Sciences of the United States of America in 2016.Quality Control of Pyridinehydrochloride This article mentions the following:

A nitrogenase-inspired biomimetic chalcogel system comprising double-cubane [Mo₂Fe₆S₈(SPh)₃] and single-cubane (Fe₄S₄) biomimetic clusters demonstrates photocatalytic N₂ fixation and conversion to NH₃ in ambient temperature and pressure conditions. Replacing the Fe₄S₄ clusters in this system with other inert ions such as Sb³⁺, Sn⁴⁺, Zn²⁺ also gave chalcogels that were photocatalytically active. Finally, molybdenum-free chalcogels containing only Fe₄S₄ clusters are also capable of accomplishing the N₂ fixation reaction with even higher efficiency than their Mo₂Fe₆S₈(SPh)₃-containing counterparts. Results suggest that redox-active iron-sulfide-containing materials can activate the N₂ mol. upon visible light excitation, which can be reduced all of the way to NH₃ using protons and sacrificial electrons in aqueous solution Evidently, whereas the Mo₂Fe₆S₈(SPh)₃ is capable of N₂ fixation, Mo itself is not necessary to carry out this process. The initial binding of N₂ with chalcogels under illumination was observed with in situ diffuse-reflectance FTIR spectroscopy (DRIFTS). ¹⁵N₂ isotope experiments confirm that the generated NH₃ derives from N₂. D. functional theory (DFT) electronic structure calculations suggest that the N₂ binding is thermodynamically favorable only with the highly reduced active clusters. The results reported herein contribute to ongoing efforts of mimicking nitrogenase in fixing nitrogen and point to a promising path in developing catalysts for the reduction of N₂ under ambient conditions. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Quality Control of Pyridinehydrochloride).

Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Quality Control of Pyridinehydrochloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Characterization of liquefied products from corn stalk in the presence of polyhydric alcohols with acid catalysis was written by Zhang, Yan;Wang, Huile;Zhao, Huifang;Liu, Zhong;Huang, Jingjun;Yang, Yujie;Chen, Yu. And the article was included in BioResources in 2022.Quality Control of 3-Amino-2,6-dimethoxypyridine This article mentions the following:

Atm. liquefaction technol. has been used widely and is an effective way of biomass component utilization. In this paper, the liquefied products obtained from corn stalk using polyhydric alcs. 1,2-propanediol (PG) mixed diethylene glycol (DEG) through acid catalysis under atm. pressure were characterized by various anal. technologies. The results indicated that 39 kinds of organic compounds were present in bio-oil, among which alcs. were the most, phenols were the second, and their relative contents were 70.7% and 25.6%, resp. There were also some organic acids, ethers, esters, and ketones. More than 80% of these compounds had a carbon number less than 25. Carbon NMR spectra (13C-NMR) showed that different chem. shifts δ (ppm) corresponded to various carbon types. The chem. composition of the residue from liquefaction was complex and contained a certain amount of large mol. substances that were difficult to degrade. It required more severe pyrolysis conditions than those of corn stalk. Results from X-Ray Diffraction (XRD) indicated the destruction of crystalline structure of carbohydrates and the cellulose mols. were cracked, indicating that the cellulose was degraded and the degree of liquefaction was high. In the experiment, the researchers used many compounds, for example, 3-Amino-2,6-dimethoxypyridine (cas: 28020-37-3Quality Control of 3-Amino-2,6-dimethoxypyridine).

3-Amino-2,6-dimethoxypyridine (cas: 28020-37-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Quality Control of 3-Amino-2,6-dimethoxypyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

A structure-activity relationship study of the toxicity of ionic liquids using an adapted Ferreira-Kiralj hydrophobicity parameter was written by Melo, Eduardo Borges de. And the article was included in Physical Chemistry Chemical Physics in 2015.Computed Properties of C7H7ClN2 This article mentions the following:

The Ferreira-Kiralj hydrophobicity parameter W_c is a number fraction of hydrophobic carbon atoms and can be regarded as a constitutional descriptor since its calculation depends only on the number of polar and nonpolar carbons in a compound Hydrophobicity is important to the toxicity of ionic liquids (ILs), which are salts by nature. Herein, a descriptor for this property was calculated using a simple adaptation of the type of polar carbon atoms included (W_cAdap) to explore the possibility of its use in quant. structure-activity relationship (QSAR) studies of ILs. The resulting model was tested using a database of ILs with toxicity against the Leukemia rat cell line IPC-81. Two other models were constructed using Crippen log P and Mannhold log P descriptors, which are both available in the free program PaDEL. The use of W_cAdap led to a better and more indicative model. Thus, W_cAdap may be a suitable mol. descriptor for the hydrophobicity of ILs in QSAR studies. In the experiment, the researchers used many compounds, for example, 1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3Computed Properties of C7H7ClN2).

1-(Cyanomethyl)pyridin-1-ium chloride (cas: 17281-59-3) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Computed Properties of C7H7ClN2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

QSTR study on aquatic toxicity against Poecilia reticulata and Tetrahymena pyriformis using topological indices was written by Costescu, Adina;Diudea, Mircea V.. And the article was included in Internet Electronic Journal of Molecular Design in 2006.SDS of cas: 15128-90-2 This article mentions the following:

Motivation: Considering the importance of quant. structure-toxicity relationship (QSTR) studies in the field of aquatic toxicol. from the viewpoint of ecol. safety assessment, fish and algae toxicity of various aromatic compounds has been modeled by the multiple regression technique. Topol. indexes are used to relate the chem. structures to their toxic activity against aquatic organisms. In our experiment we do not look for the best model for a property on a given set of mols., but for the best set of descriptors modeling a given functional group. Method: Correlation anal. and Multiple Linear Regression (MLR) have been carried out to derive the best QSAR models, giving important information on functional groups by topol. descriptors. The models belonging to benzene derivative toxicity against Poecilia reticulata were validated with an external validation set, and the indexes in the best models were used to predict the toxicity for other two sets of aromatic compounds against Tetrahymena pyriformis. The robustness and prediction power of each model was evaluated by a leave-half-out (LHO) procedure. Results: The classification performance of topol. descriptor models generated with multiple regressions show that the statistical results depend strongly on the functional groups description. The basic set, toxicity data of 92 diverse aromatic compounds against Poecilia reticulata, provided very good results witch were validated more then 93%. For the both prediction sets against Tetrahymena pyriformis the best models are: R = 0.98; R² = 0.96; Q² = 0.94; F = 188.36; s = 0.13 (the set with 37 nitrobenzene derivatives) and R = 0.92; R² = 0.84; Q² = 0.82; F = 198.64; s = 0.2 (for 167 aromatic compounds). Conclusions: Our statistical study demonstrated that topol. indexes based on Cluj matrixes show a good predictive ability of the aquatic toxicity against Poecilia reticulata and Tetrahymena pyriformis. These indexes account for mol. bulk, halogen, nitro and amino substitutions in the benzene ring. The four descriptors that describe the equation of nitrobenzene derivative are very useful to predict the activity of other compounds containing the nitro functional group. It appears that topol. descriptors have significant potential in QSTR studies, which warrants extensive evaluation. This procedure can be used to approach the aquatic toxicity and to select the appropriate model for new chem. compounds In the experiment, the researchers used many compounds, for example, 3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2SDS of cas: 15128-90-2).

3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2) belongs to pyridine derivatives. Pyridine has a dipole moment and a weaker resonant stabilization than benzene (resonance energy 117 kJ·mol−1 in pyridine vs. 150 kJ·mol−1 in benzene). Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.SDS of cas: 15128-90-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Catalytic Fast Pyrolysis of Sewage Sludge over HZSM-5: A Study of Light Aromatics, Coke, and Nitrogen Migration under Different Atmospheres was written by Gu, Bo;Cao, Jing-Pei;Shan, Yi-Fu;Wei, Fu;Zhao, Ming;Zhao, Yun-Peng;Zhao, Xiao-Yan;Wei, Xian-Yong. And the article was included in Industrial & Engineering Chemistry Research in 2020.Recommanded Product: 2-Isopropylpyridine This article mentions the following:

catalytic fast pyrolysis of wastewater sludge was conducted to assess pyrolysis temperature and atm., and catalysts effect on C and N distribution in a fixed-bed reactor. a H₂ atmosphere had the lowest C selectivity of solid products and the highest gaseous product yield over HZSM-5 (HZ) at the same temperature vs. Ar and steam atmospheres. higher temperature led to increased C selectivity of gaseous products and decreased C selectivity of solids. H₂ increased the C yield of light aromatics (LA); steam reduced generation of LA. over 0.5 Ni-HZ, H₂ had the highest LA C yield (11.4%) vs. 1.6% from non-catalytic fast pyrolysis of sludge. higher temperatures, H₂ and steam atmospheres, and metal-loaded HZ promoted N transfer to gaseous products. the highest N yield (i.e., NH₃) of 55.6% was obtained from sludge pyrolysis over HZ at 700° in a H₂ atmosphere. In the experiment, the researchers used many compounds, for example, 2-Isopropylpyridine (cas: 644-98-4Recommanded Product: 2-Isopropylpyridine).

2-Isopropylpyridine (cas: 644-98-4) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Recommanded Product: 2-Isopropylpyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem