Tag: 200-300

In 2016,Popowski, Yanay; Goldberg, Israel; Kol, Moshe published 《The stereoselectivity of bipyrrolidine-based sequential polydentate ligands around Ru(II)》.Chemical Communications (Cambridge, United Kingdom) published the findings.Product Details of 31106-82-8 The information in the text is summarized as follows:

The Ru(II) coordination chem. of the sequential hexadentate, tetradentate and the novel hybrid pentadentate ligands assembled around the chiral bipyrrolidine core and including bipyridyl and pyridyl periphery units is described. The bipyridine group exhibited priority in binding over the bipyrrolidine group, which led to a diastereomer mixture in the case of the hexadentate ligand (R,R)-bis(bipyridinylmethyl)-2,2′-bipyrrolidine (1). Employing only monopyridyl or a combination of monopyridyl (3) and bipyridyl (4) peripheral groups restored the chiral induction ability to the bipyrrolidine core resulting in predetermined chiral-at-metal complexes. In addition to this study using 2-(Bromomethyl)pyridine hydrobromide, there are many other studies that have used 2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8Product Details of 31106-82-8) was used in this study.

2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Product Details of 31106-82-8

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Siddique, Rashid G.; Arachchige, Kasun S. A.; AL-Fayaad, Hydar A.; Brock, Aidan J.; Micallef, Aaron S.; Luis, Ena T.; Thoburn, John D.; McMurtrie, John C.; Clegg, Jack K. published an article in 2021. The article was titled 《The kinetics and mechanism of interconversion within a system of [Fe2L3]4+ helicates and [Fe4L6]8+ cages》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Recommanded Product: 624-28-2 The information in the text is summarized as follows:

Nature builds simple mols. into highly complex assemblies, which are involved in all fundamental processes of life. Some of the most intriguing biol. assemblies are those that can be precisely reconfigured to achieve different functions using the same building blocks. Understanding the reconfiguration of synthetic self-assembled systems will allow us to better understand the complexity of proteins and design useful artificial chem. systems. Here the authors prepared a relatively simple system in which two distinct self-assembled structures, a [Fe2L3]4+ helicate and a [Fe4L6]8+ cage that are formed from the same precursors, coexist at equilibrium, L is bisbipyrinyldiethynylbenzene. The authors measured the rates of interconversion of these two species and propose a mechanism for the transformation. The results came from multiple reactions, including the reaction of 2,5-Dibromopyridine(cas: 624-28-2Recommanded Product: 624-28-2)

2,5-Dibromopyridine(cas: 624-28-2) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.Recommanded Product: 624-28-2

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2012,Delcamp, Jared H.; Yella, Aswani; Nazeeruddin, Mohammad K.; Graetzel, Michael published 《Modulating dye E(S+/S*) with efficient heterocyclic nitrogen containing acceptors for DSCs》.Chemical Communications (Cambridge, United Kingdom) published the findings.Category: pyridine-derivatives The information in the text is summarized as follows:

Acceptor motifs based on nitrogen containing heterocycles have been synthesized for use in dye-sensitized solar cells (DSCs). Through the selective addition of nitrogen atoms and increased conjugation of the nitrogen containing heterocycles the excited-state oxidation potential, E(S+/S*), may be conveniently tuned with minimal effect on the ground-state oxidation potential, E(S+/S), of the dye. The experimental process involved the reaction of Methyl 5-bromopicolinate(cas: 29682-15-3Category: pyridine-derivatives)

Methyl 5-bromopicolinate(cas: 29682-15-3) belongs to pyridine. Pyridine is very deactivated towards electrophilic substitution with respect to benzene. For this reason classical formylation, using methods such as the Gattermann or Vilsmeier reactions, are not generally successful. Category: pyridine-derivatives

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

The author of 《A boron-centered radical: a potassium-crown ether stabilized boryl radical anion》 were Yuan, Ningning; Wang, Wenqing; Wu, Ziye; Chen, Sheng; Tan, Gengwen; Sui, Yunxia; Wang, Xinping; Jiang, Jun; Power, Philip P.. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2016. Safety of 4-Bromo-3,5-dimethylpyridine hydrochloride The author mentioned the following in the article:

A boron radical contact ion-pair Mes2B{4-(3,5-dimethylpyridinyl)}K(18-crown-6)(THF) (1K) was isolated and characterized by ESR spectroscopy, UV-visible absorption spectroscopy and single crystal x-ray diffraction. The geometry, bonding and spin d. distribution are affected by the N···K interaction. The unpaired electron resides mainly on the boron atom and falls between those of triarylboron radical anions and neutral boron radicals. The work provides a novel boron-centered radical intermediate, connecting anionic and neutral boryl radicals. The experimental part of the paper was very detailed, including the reaction process of 4-Bromo-3,5-dimethylpyridine hydrochloride(cas: 1794738-16-1Safety of 4-Bromo-3,5-dimethylpyridine hydrochloride)

4-Bromo-3,5-dimethylpyridine hydrochloride(cas: 1794738-16-1) belongs to pyridine. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year.Safety of 4-Bromo-3,5-dimethylpyridine hydrochloride

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Zirconium bistriazolylpyridine phosphonate materials for efficient, selective An(III)/Ln(III) separations》 was written by Veliscek-Carolan, Jessica; Rawal, Aditya. Electric Literature of C5H3Br2NThis research focused onzirconium triazolylpyridinephosphonate complex preparation porosity adsorption surface structure. The article conveys some information:

Direct synthesis of ZrCl4 and bistriazolylpyridine phosphonate has produced novel sorbent materials that, for the first time, demonstrate selective extraction of Am(III) in the presence of excess Eu(III). Further, the high ligand content of these materials affords them high extraction efficiencies. In the part of experimental materials, we found many familiar compounds, such as 2,6-Dibromopyridine(cas: 626-05-1Electric Literature of C5H3Br2N)

2,6-Dibromopyridine(cas: 626-05-1) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Electric Literature of C5H3Br2N

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《Synthesis, characterization and introduction of a new ion-coordinating ruthenium sensitizer dye in quasi-solid state TiO2 solar cells》 was published in Journal of Photochemistry and Photobiology, A: Chemistry in 2011. These research results belong to White, Ryan C.; Benedetti, Joao E.; Goncalves, Agnaldo D.; Romao, Wanderson; Vaz, Boniek G.; Eberlin, Marcos N.; Correia, Carlos R. D.; De Paoli, Marco A.; Nogueira, Ana F.. Application of 138219-98-4 The article mentions the following:

A new ion-coordinating heteroleptic ruthenium(II) dye was synthesized by attaching two crown ether moieties in the 4,4′ positions of one of the bipyridine ligands. This new dye (named as RC730) was characterized by UV-Vis spectroscopy, CHN elemental anal., NMR and electrospray ionization Fourier transform-ion cyclotron resonance mass spectrometry (ESI FT-ICR MS). In order to investigate the properties of these ion-coordinating species, dye-sensitized solar cells were assembled with a gel polymer electrolyte based on two different cations: lithium and sodium. The devices were characterized by J-V curves under 100 mW cm-2, incident photon to current conversion efficiency spectra (IPCE) and photovoltage decay transients under open-circuit conditions. The solar cells based on the new heteroleptic dye provided higher photocurrent and photovoltage when lithium was used in the electrolyte instead of sodium cations, reaching overall conversion efficiencies up to 2%. This behavior might be related to the ability of the ion-coordinating RC730 dye to trap Li ions, minimizing the conduction band edge shift. When the polymer electrolyte based on lithium is used, the IPCE spectra show a maximum efficiency of 31% at the maximum absorption peak of the RC730 dye (ca. 530 nm). After reading the article, we found that the author used 4,4′-Bis(chloromethyl)-2,2′-bipyridine(cas: 138219-98-4Application of 138219-98-4)

4,4′-Bis(chloromethyl)-2,2′-bipyridine(cas: 138219-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. Application of 138219-98-4 Pyridine has a conjugated system of six π electrons that are delocalized over the ring.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

HPLC of Formula: 138219-98-4On November 25, 2013 ,《Structure-Activity Relationships and Identification of Optmized CC-Chemokine Receptor CCR1, 5, and 8 Metal-Ion Chelators》 appeared in Journal of Chemical Information and Modeling. The author of the article were Chalikiopoulos, Alexander; Thiele, Stefanie; Malmgaard-Clausen, Mikkel; Rydberg, Patrik; Isberg, Vignir; Ulven, Trond; Frimurer, Thomas M.; Rosenkilde, Mette M.; Gloriam, David E.. The article conveys some information:

Chemokine receptors are involved in trafficking of leukocytes and represent targets for autoimmune conditions, inflammatory diseases, viral infections, and cancer. We recently published CCR1, CCR8, and CCR5 agonists and pos. modulators based on a three metal-ion chelator series: 2,2′-bipyridine, 1,10-phenanthroline, and 2,2′;6′,2”-terpyridine. Here, we have performed an in-depth structure-activity relationship study and tested eight new optimized analogs. Using d. functional theory calculations we demonstrate that the chelator zinc affinities depend on how electron-donating and -withdrawing substituents modulate the partial charges of chelating nitrogens. The zinc affinity was found to constitute the major factor for receptor potency, although the activity of some chelators deviate suggesting favorable or unfavorable interactions. Hydrophobic and halogen substituents are generally better accommodated in the receptors than polar groups. The new analog brominated terpyridine (29) resulted in the highest chelator potencies observed so far CCR1 (EC50: 0.49 μM) and CCR8 (EC50: 0.28 μM). Furthermore, we identified the first selective CCR5 agonist chelator, meta dithiomethylated bipyridine (23). The structure-activity relationships contribute to small-mol. drug development, and the novel chelators constitute valuable tools for studies of structural mechanisms for chemokine receptor activation. The results came from multiple reactions, including the reaction of 4,4′-Bis(chloromethyl)-2,2′-bipyridine(cas: 138219-98-4HPLC of Formula: 138219-98-4)

4,4′-Bis(chloromethyl)-2,2′-bipyridine(cas: 138219-98-4) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. HPLC of Formula: 138219-98-4 Pyridine has a conjugated system of six π electrons that are delocalized over the ring.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

《H3PW12O40: an efficient and green catalyst for the facile and selective oxidation of sulfides to sulfoxides, applied to the last step of the synthesis of omeprazole》 was published in Iranian Journal of Chemistry & Chemical Engineering in 2017. These research results belong to Esfandyari, Maryam; Heravi, Majid; Oskooie, Hossein; Fotouhi, Lida; Tajbakhsh, Mahmood; Bamoharram, Fatemeh. Name: 2-(Chloromethyl)-3,5-dimethyl-4-nitropyridine The article mentions the following:

Omeprazole, (6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzimidazole) is a well-established prescribed drug, exhibits proton pump inhibitor activity. In this work, a novel, facile, economical and selective oxidation approach using H3PW12O40 as Keggin type heteropolyacids along with H2O2 in the last step of the conventional synthesis of this compound as well as its derivatives under environmental-benign conditions, is reported. This protocol can be well adopted for pilot plant scale giving a high pure pharmacopeia grade material. Our synthetic route involves the use of various heteropolyacids as heterogeneous catalysts. Due to the obtained results, it was concluded that Keggin type heteropolyacid , is an effective catalyst for this purpose. The optimized condition for the last step of this synthesis was applied to the synthesis of lansoprazole, pantoprazole, and rabeprazole. The experimental part of the paper was very detailed, including the reaction process of 2-(Chloromethyl)-3,5-dimethyl-4-nitropyridine(cas: 153476-68-7Name: 2-(Chloromethyl)-3,5-dimethyl-4-nitropyridine)

2-(Chloromethyl)-3,5-dimethyl-4-nitropyridine(cas: 153476-68-7) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Name: 2-(Chloromethyl)-3,5-dimethyl-4-nitropyridine

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

In 2017,Liu, Boao; Dang, Feifan; Feng, Zhao; Tian, Zhuanzhuan; Zhao, Jiang; Wu, Yong; Yang, Xiaolong; Zhou, Guijiang; Wu, Zhaoxin; Wong, Wai-Yeung published 《Novel iridium(III) complexes bearing dimesitylboron groups with nearly 100% phosphorescent quantum yields for highly efficient organic light-emitting diodes》.Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published the findings.SDS of cas: 29682-15-3 The information in the text is summarized as follows:

A series of cyclometalated iridium (III) complexes, Ir-B-1, Ir-B-2, Ir-B-3, and Ir-B-4, were synthesized with the 2-phenylpyridine (ppy) type main ligand possessing a dimesitylboron group and the auxiliary ligand containing other main-group element units showing unique charge injection/transporting features. Their thermal stability, photophys. and electrochem. properties, and electroluminescent (EL) performances have been characterized. Time-dependent d. functional theory (TD-DFT) calculations were carried out to study the photophys. properties of these complexes. All these complexes can emit intense orange phosphorescence with extremely high quantum yields of nearly 100% measured in neat films at room temperature Moreover, the solution-processed organic light-emitting devices (OLEDs) using these complexes as orange emitters can show very high EL efficiencies with the maximum luminance efficiency (ηL) of 85.1 cd A-1, corresponding to a power efficiency (ηP) of 69.7 lm W-1 and an external quantum efficiency (ηext) of 28.1%. In the part of experimental materials, we found many familiar compounds, such as Methyl 5-bromopicolinate(cas: 29682-15-3SDS of cas: 29682-15-3)

Methyl 5-bromopicolinate(cas: 29682-15-3) belongs to pyridine. Pyridine is a relatively complex molecule and exhibits a number of different bands in IR spectra. Among others, the bands characterizing the ν8a and ν19b modes have been found to be sensitive to the coordination or protonation of the molecule. Note that the band that is diagnostic for the PyH+ ion at about 1545 cm− 1 (ν19b mode) does not overlap with any of the other bands.SDS of cas: 29682-15-3

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Safety of 2-(Bromomethyl)pyridine hydrobromideIn 2017 ,《Pyridine-antipyrine appended indole derivative for selective recognition of Fe3+: Concentration dependent coloration》 appeared in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy. The author of the article were Ta, Sabyasachi; Nandi, Sandip; Ghosh, Milan; Banerjee, Somenath; Das, Debasis. The article conveys some information:

Combination of pyridine, antipyrine and indole in a single mol. (L2) allows selective recognition of Fe3 + colorimetrically in CH3CN. The structure of L2 is confirmed from single crystal x-ray diffraction anal. The probe displays two different visible bands at 541 nm and 715 nm in the presence of Fe3 +, associated with two different colors, viz. green and pink-violet allowing determination of unknown Fe3 + concentration Removal of 2-picolyl group from indole N-center of L2 generates L3 that behaves similarly at low Fe3 + concentration (> 0 to 1.1 mM) but differently at higher Fe3 + concentration (> 1.1 mM), indicating involvement of pyridyl-N donor towards Fe3 +, and hence different coordination environment around Fe3 + at higher concentration In the experiment, the researchers used 2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8Safety of 2-(Bromomethyl)pyridine hydrobromide)

2-(Bromomethyl)pyridine hydrobromide(cas: 31106-82-8) belongs to pyridine. The basicity and metallophilic high donor number of these π-deficient systems has long favored them as ligands in metal catalysis. The last decade saw pyridine assume a stronger role as functional group for directed C–H oxidation/activation.Safety of 2-(Bromomethyl)pyridine hydrobromide

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem