Tag: M.W=100-150

Forlani, Luciano; Cristoni, Giampiero; Boga, Carla; Todesco, Paolo E.; Del Vecchio, Erminia; Selva, Simona; Monari, Magda published the artcile< Reinvestigation of the tautomerism of some substituted 2-hydroxypyridines>, Formula: C5H4ClNO, the main research area is UV NMR spectrometry tautomerism substituted hydroxypyridines LFER; crystallog nitropyridinone.

The tautomerism of some substituted 2-hydroxypyridines is investigated by UV/Vis- and 1H-, and 13C-NMR spectroscopic methods, with the aid of the N-Me and O-Me fixed parents. NMR spectroscopic data do not allow discrimination between the two tautomeric forms (with the exception of the unsubstituted 2-hydroxypyridine), while UV/Vis-data permit the quant. determination, in different solvents, of the amounts of the two forms. The electronic substituent effect and the change of solvent are discussed. An X-Ray diffraction study carried out on a crystal of 2-hydroxy-5-nitropyridine (7) reveals that this compound, in the solid state, is in the oxo-form.

ARKIVOC (Gainesville, FL, United States) [online computer file] published new progress about Crystal structure. 73018-09-4 belongs to class pyridine-derivatives, and the molecular formula is C5H4ClNO, Formula: C5H4ClNO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Proctor, Rupert S. J.; Chuentragool, Padon; Colgan, Avene C.; Phipps, Robert J. published the artcile< Hydrogen Atom Transfer-Driven Enantioselective Minisci Reaction of Amides>, Quality Control of 93-60-7, the main research area is amide heteroarene chiral phosphoric acid diacetyl light Minisci reaction; heteroarenyl alkyl amide stereoselective preparation.

Minisci-type reactions constitute one of the most powerful methods for building up complexity around basic heteroarenes. The most desirable variants involve formal oxidative coupling of a C-H bond on each partner, leading back to the simplest possible starting materials. We herein disclose a method that enables such a coupling of linear amides and heteroarenes with full control of enantioselectivity at the newly formed stereocenter as well as site selectivity on both the heteroarene and the amide. This is achieved by the use of a chiral phosphoric acid catalyst in conjunction with diacetyl as a combined hydrogen atom transfer reagent and oxidant. Diacetyl is directly photoexcitable, and thus, no extraneous photocatalyst is required: an added feature that contributes to the simplicity and practicality of the protocol.

Journal of the American Chemical Society published new progress about Amides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Quality Control of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Akporji, Nnamdi; Thakore, Ruchita R.; Cortes-Clerget, Margery; Andersen, Joel; Landstrom, Evan; Aue, Donald H.; Gallou, Fabrice; Lipshutz, Bruce H. published the artcile< N2Phos - an easily made, highly effective ligand designed for ppm level Pd-catalyzed Suzuki-Miyaura cross couplings in water>, Electric Literature of 13472-84-9, the main research area is phosphine biaryl ligand preparation crystal structure mol; biaryl preparation; aryl halide arylboronic acid Suzuki Miyaura palladium catalyst.

A new biaryl phosphine-containing ligand from an active palladium catalyst for ppm level Suzuki-Miyaura couplings to afford biaryls, was enabled by an aqueous micellar reaction medium. A wide array of functionalized substrates including aryl/heteroaryl bromides were amenable, as were, notably, chlorides. The catalytic system was both general and highly effective at low palladium loadings (1000-2500 ppm or 0.10-0.25 mol%). D. functional theory calculations suggested that greater steric congestion in N2Phos induced increased steric crowding around the Pd center, helping to destabilize the 2 : 1 ligand-Pd(0) complex more for N2Phos than for EvanPhos (and less bulky ligands), and thereby favoring formation of the 1 : 1 ligand-Pdo complex that is more reactive in oxidative addition to aryl chlorides.

Chemical Science published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 13472-84-9 belongs to class pyridine-derivatives, and the molecular formula is C6H6ClNO, Electric Literature of 13472-84-9.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Kumar, Ajay; Sahoo, Subash Chandra; Mehta, Surinder Kumar; Soni, Parmod; Sharma, Vishal; Kataria, Ramesh published the artcile< A luminescent Zn-MOF for the detection of explosives and development of fingerprints>, Related Products of 3731-53-1, the main research area is zinc metal organic framework explosive detection fingerprint.

A luminescent 3D metal-organic framework [Zn(NDA)(AMP)] = PUC1 (where, NDA = naphthalene-2,6-dicarboxylic acid and AMP = 4-aminomethyl pyridine) was synthesized under solvothermal conditions. The synthesized 3D framework was fully characterized with the help of different anal. techniques such as SCXRD, FTIR, TGA, PXRD, SEM, BET, etc. PUC1 exhibited a strong emission peak at 371 nm when excited at 290 nm and the resulting emission was efficiently quenched in the presence of various organic explosive substances like pentaerythritol tetranitrate (PETN), 2,4,6-trinitrophenyl-N-methylnitramine (Tetryl), trinitrotoluene (TNT), 1,3,5-trinitroperhydro-1,3,5-triazine (RDX), and 1,3,5,7-tetranitro-1,3,5,7-tetrazoctane (HMX). PUC1 revealed highly sensitive and selective detection of PETN and Tetryl with high quenching constant values of 0.1 x 106 and 0.12 x 105 M-1 and low detection limits of 0.315 and 0.404 μM resp. The strong luminescent properties of PUC1 lead to its successful application in the development of latent fingermarks on different non-porous surfaces using the powder dusting method. The accuracy and applicability of the synthesized material were determined by developing fingerprints by using secretions from eccrine and apocrine glands on a glass slide and various other surfaces, followed by dusting the surfaces. The results so obtained were found to be very accurate and promising.

Analytical Methods published new progress about Crystallinity. 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Related Products of 3731-53-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Nallagonda, Rajender; Karimov, Rashad R. published the artcile< Copper-Catalyzed Regio- and Diastereoselective Additions of Boron-Stabilized Carbanions to Heteroarenium Salts: Synthesis of Azaheterocycles Containing Contiguous Stereocenters>, Recommanded Product: 3-(Methoxycarbonyl)pyridine, the main research area is nonaromatic nitrogen heterocycle preparation diastereoselective addition boron carbanion heteroarenium.

Nucleophilic addition of diborylalkyl reagents to N-alkyl or N-acylpyridinium and related heteroarenium salts has been developed as a key step for the synthesis of nonaromatic nitrogen heterocycles that contain contiguous stereogenic centers. Derivatization of the dihydropyridine products for the synthesis of tetrahydropyridines and piperidines have also been described.

ACS Catalysis published new progress about Boranes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (alkyl). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Recommanded Product: 3-(Methoxycarbonyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Phuan, P.-W.; Kozlowski, M. C. published the artcile< Product class 8: naphthyridines>, Product Details of C6H6N2O, the main research area is review naphthyridine cyclization ring transformation.

A review of synthetic methods to prepare naphthyridines which include cyclization and ring transformations.

Science of Synthesis published new progress about 55279-29-3. 55279-29-3 belongs to class pyridine-derivatives, and the molecular formula is C6H6N2O, Product Details of C6H6N2O.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Sharma, Rahul; Mondal, Avijit; Samanta, Arup; Biswas, Nandita; Das, Babulal; Srimani, Dipankar published the artcile< Well-Defined Ni-SNS Complex Catalyzed Borrowing Hydrogenative α-Alkylation of Ketones and Dehydrogenative Synthesis of Quinolines>, Product Details of C7H7NO, the main research area is nickel catalyst preparation crystal structure; acetophenone alc nickel catalyst alkylation; aryl alkyl ketone preparation green chem; ketone aminophenyl methanol nickel catalyst alkylation; quinoline preparation green chem.

Here presented a synthesis of non-phosphine, easily accessible and bench stable SNS-Ni complexes. The Ni-catalyst was successfully applied for the C-alkylation of ketone enolates to α-alkylated ketones. Primary alc. with different functional groups and various heteroaromatic alcs. were well tolerated. The present catalyst system was efficiently applied to gram scale synthesis and also the green chem. metrics of the reaction were calculated The present protocol was also extended successfully for the synthesis of biol. important quinoline moieties. Finally, various control experiments and deuterium labeled experiments suggested that the reaction proceeds via borrowing hydrogen pathway.

Advanced Synthesis & Catalysis published new progress about Alkylation. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Product Details of C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mkrtchyan, Satenik; Jakubczyk, Michal; Lanka, Suneel; Yar, Muhammad; Ayub, Khurshid; Shkoor, Mohanad; Pittelkow, Michael; Iaroshenko, Viktor O. published the artcile< Mechanochemical Transformation of CF3 Group: Synthesis of Amides and Schiff Bases>, Recommanded Product: 3-(Trifluoromethyl)pyridine, the main research area is trifluoromethyl group nitro compound ytterbium catalyst mechanochem coupling transformation; amide preparation; methanimine preparation; indole preparation.

Two mild, solvent-free mechanochem. coupling transformations of CF3 group with nitro compounds into amides or Schiff bases employing Ytterbia as a catalyst were reported. This process proceeded via C-F bond activation, accompanied with utilization of Si-based reductants/oxygen scavengers – reductants of the nitro group. The scope and limitations of the disclosed methodologies were thoroughly studied. To the best of author knowledge, this work was the first example of mech. energy promoted transformation of the inert CF3 group into other functionalities.

Advanced Synthesis & Catalysis published new progress about Amides Role: SPN (Synthetic Preparation), PREP (Preparation). 3796-23-4 belongs to class pyridine-derivatives, and the molecular formula is C6H4F3N, Recommanded Product: 3-(Trifluoromethyl)pyridine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zhou, Changjian; Sun, Rong; Zhang, Yuting; Xiong, Biao; Dai, Hui; Dai, Yong published the artcile< Co-N-Si/AC Catalyst for Aerobic Oxidation of Benzyl Alcohols to Esters under Mild Conditions>, Reference of 93-60-7, the main research area is ester preparation green chem; benzyl alc aerobic oxidative esterification cobalt catalyst; aerobic oxidation; benzyl alcohols; heterogeneous cobalt.

A stable, earth-abundant, reusable cobalt-based heterogeneous catalyst is developed for the oxidative esterification of alcs. RCH2OH (R = Ph, naphthalen-1-yl, thiophen-2-yl, etc.) under ambient conditions, featuring broad substrate scope, providing good to excellent product yields. This protocol enables easy recyclability of the catalyst, measured up to five times without significant loss of efficiency. The active sites of Co-N-Si/AC are proposed to be Co-N species.

Molecules published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Reference of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Nie, Xufeng; Zheng, Yanling; Ji, Li; Fu, Haiyan; Chen, Hua; Li, Ruixiang published the artcile< Acceptorless dehydrogenation of amines to nitriles catalyzed by N-heterocyclic carbene-nitrogen-phosphine chelated bimetallic ruthenium (II) complex>, Name: Pyridin-4-ylmethanamine, the main research area is heterocyclic carbene nitrogen phosphine chelate bimetallic ruthenium complex preparation; amine ruthenium complex catalyst dehydrogenation green chem; nitrile preparation.

A clean, atom-economical and environmentally friendly route for acceptorless dehydrogenation of amines to nitriles by combining a new dual N-heterocyclic carbene-nitrogen-phosphine ligand R(CNP)2 (R = o-xylyl) with a ruthenium precursor [RuCl2(η6-C6H6)]2 was developed. In this system, the electronic and steric factors of amines had a negligible influence on the reaction and a broad range of functional groups were well tolerated. All of the investigated amines was converted to nitriles in good yield of up to 99% with excellent selectivity. The unprecedented catalytic performance of this system was attributed to the synergistic effect of two ruthenium centers chelated by R(CNP)2 and a plausible reaction mechanism was proposed according to the active species found via in-situ NMR and HRMS.

Journal of Catalysis published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, Name: Pyridin-4-ylmethanamine.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem