Tag: M.W=100-150

Looga, A. M.; Ambassa, P.; Kamga, J.; Hortense, GK.; Ngadjui, B. T.; Ngameni, B. published the artcile< Synthesis and evaluation of antimicrobial properties of some novel indole pyridine based chalcones>, SDS of cas: 350-03-8, the main research area is chalcone indole pyridine diastereoselective preparation antibacterial antifungal; indolyl pyridinyl propenone preparation diastereoselective antibacterial antifungal activity.

A series of novel substituted indolylchalcone derivatives (E)-I (R = H, Me, Ar = pyridin-3-yl, pyridin-4-yl) were synthesized via Claisen-Schmidt condensation between indole-3-carbaldehyde and N-methylindole-3-carbaldehyde and 3- and 4-pyridinylacetophenones. All the compounds were screened for their antibacterial and antifungal activity against six different bacterial strains – Escherichia coli ATCC 25922, Klebsiella pneumonia ATCC 700603, Staphylococcus aureus ATCC 25923, Proteus mirabilis, Salmonella typhi, Pseudomonas aeruginosa – and against one fungal strain, Candida albicans. The results reveal that all the compounds exhibited moderate to good antibacterial and antifungal activities.

Austin Journal of Analytical and Pharmaceutical Chemistry published new progress about Antibacterial agents. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, SDS of cas: 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Duong, Thi-Mai Huong; Nobusue, Shunpei; Tada, Hirokazu published the artcile< Preparation of perovskite-derived one dimensional single crystals based on edge-shared octahedrons with pyridine derivatives>, HPLC of Formula: 3731-53-1, the main research area is lead pyridine derivative iodo complex perovskite preparation crystal structure; optical band gap lead pyridine derivative iodo complex perovskite.

Single crystals of hybrid materials based on 1D lead iodide perovskite networks with 2 pyridine (Py) derivatives, 4-Et (4Et)Py and 4-aminomethyl (4AM)Py, were prepared The compounds assembled into edge-shared lead iodide chains that formed needle-shaped crystals with lengths >1 cm. The crystal containing (4Et)Py formed in the triclinic system with P1 symmetry. The mols. were stacked along with the novel triple chain of 1D perovskite-derived networks. The crystal containing 4AMPy formed in the monoclinic system with P21/a symmetry. The amino group formed H bonds to I-. The optical band gaps for the 4EtPy-based and 4AMPy-based crystals are 2.73 eV and 2.64 eV, resp. The slight difference between the functional groups of the 2 mols. governed their crystal structures and hence optical properties.

Journal of Crystal Growth published new progress about Crystal structure. 3731-53-1 belongs to class pyridine-derivatives, and the molecular formula is C6H8N2, HPLC of Formula: 3731-53-1.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Zhang, Guoqi; Cheng, Jessica; Davis, Kezia; Bonifacio, Mary Grace; Zajaczkowski, Cynthia published the artcile< Practical and selective hydroboration of aldehydes and ketones in air catalysed by an iron(II) coordination polymer>, Product Details of C7H7NO, the main research area is hydroboration aldehyde ketone green chem iron coordination polymer catalyst.

The in air catalytic hydroboration of ketones and aldehydes with pinacolborane by an iron(II) coordination polymer (CP) is carried out under mild and solvent-free conditions. The precatalyst is highly active towards a wide range of substrates including functionalized ketones and aldehydes in the presence of KOtBu as an activator, achieving a high turnover number (TON) of up to 9500. Excellent chemoselectivity to aldehydes over ketones was also revealed, which is in sharp contrast with the results obtained under inert atm. using the same catalyst system. This catalyst observed here is not only highly efficient but also recyclable for reuse for at least 5 times without losing its effectiveness.

Green Chemistry published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Product Details of C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Pitre, Spencer P.; Muuronen, Mikko; Fishman, Dmitry A.; Overman, Larry E. published the artcile< Tertiary Alcohols as Radical Precursors for the Introduction of Tertiary Substituents into Heteroarenes>, Computed Properties of 93-60-7, the main research area is tertiary alkyl substituted heterocycle preparation; heterocycle tertiary alc oxalate radical alkylation photocatalyst.

Despite many recent advances in the radical alkylation of electron-deficient heteroarenes since the seminal reports by Minisci and co-workers, methods for the direct incorporation of tertiary alkyl substituents into nitrogen heteroarenes are limited. This report describes the use of tert-alkyl oxalate salts, derived from tertiary alcs., to introduce tertiary substituents into a variety of heterocyclic substrates. This reaction has reasonably broad scope, proceeds rapidly under mild conditions, and is initiated by either photochem. or thermal activation. Insights into the underlying mechanism of the higher yielding visible-light initiated process were obtained by flash photolysis studies, whereas computational studies provided insight into the reaction scope.

ACS Catalysis published new progress about Computational chemistry. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Computed Properties of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Gautam, Varsha; Kumar, Avshish; Kumar, Ramesh; Husain, Mushahid; Jain, Vinod Kumar; Nagpal, Suman published the artcile< Ultrafast trace-level detection of methyl nicotinate biomarker using TiO2/SiNWs nanocomposite-based sensing platform>, Product Details of C7H7NO2, the main research area is titanium dioxide silicon nanowire nanocomposite methyl nicotinate biomarker detection.

The reported work presents an ultrafast and ultrasensitive sensing platform for the precise and reliable trace-level detection of Me nicotinate (MN) leading to early stage diagnosis of Tuberculosis (TB). The design and fabrication of the sensor was done using silicon nanowires (SiNWs) and titanium dioxide (TiO2) nanoparticles-based nanocomposite. The structural morphol. and elemental anal. of the fabricated sensor were done using various characterization tools such as SEM (SEM), transmission electron microscopy (TEM), Fourier transform IR spectroscopy (FTIR), energy dispersive X-ray spectroscopy (EDX), Energy Dispersive X-Ray Analyzer (EDA) and X-ray diffraction (XRD). With a very precise limit of detection (LOD) (10 ppb), the sensor response was observed to be 1.02. The fabricated TiO2/SiNWs sensor demonstrates good accuracy and reproducibility along with very fast response and recovery time, i.e., 20s and 30s, resp. Hence, the results reported in the present work and the developed sensing platform using TiO2/SiNWs nanocomposite could be utilized for reliable and precise identification of TB at an early stage.

Journal of Materials Science: Materials in Electronics published new progress about Adsorption. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Product Details of C7H7NO2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Li, Wendian; Yang, Hailong; Li, Ruihao; Lv, Hui; Zhang, Xumu published the artcile< Kinetic Resolution of Racemic 3,4-Disubstituted 1,4,5,6-Tetrahydropyridine and 3,4-Disubstituted 1,4- Dihydropyridines via Rh-Catalyzed Asymmetric Hydrogenation>, Application In Synthesis of 93-60-7, the main research area is piperidine tetrahydropyridine preparation; tetrahydropyridine dihydropyridine asym hydrogenation rhodium catalyst.

Kinetic resolution of racemic 3,4-disubstituted 1,4,5,6-tetrahydropyridines and 3,4-disubstituted 1,4-dihydropyridines was developed by Rh-catalyzed asym. hydrogenation, affording chiral 3,4-disubstituted piperidines and chiral 3,4-disubstituted 1,4,5,6-tetrahydropyridines with high selectivity factors (s = up to 1057). Remarkably, all four stereoisomers of 3,4-disubstituted piperidine can be easily prepared using this method. Furthermore, the synthetic utility of this methodol. was demonstrated by efficient synthesis of antidepressant drug (-)-paroxetine.

ACS Catalysis published new progress about Diastereoselective synthesis. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Application In Synthesis of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Mondal, Rakesh; Chakraborty, Gargi; Guin, Amit Kumar; Pal, Subhasree; Paul, Nanda D. published the artcile< Iron catalyzed metal-ligand cooperative approaches towards sustainable synthesis of quinolines and quinazolin-4(3H)-ones>, Quality Control of 350-03-8, the main research area is quinoline quinazolinone preparation; alc ketone aminobenzamide dehydrogenative coupling iron catalyst metal ligand.

Herein authors report simple, efficient, and economically affordable metal-ligand cooperative strategies for synthesizing quinolines and quinazolin-4(3H)-ones via dehydrogenative functionalization of alcs. Various polysubstituted quinolines and quinazolin-4(3H)-ones were prepared in good yields via dehydrogenative coupling of readily available alcs. with ketones and 2-aminobenzamides, resp. under air using a well-defined Fe(II)-catalyst, ([FeL1Cl2]) bearing a redox-active azo-aromatic pincer 2-((4-chlorophenyl), (diazenyl)-1,10-phenanthroline) (L1). Control experiments and mechanistic investigation disclose that the one-electron reduced mono-anionic species [1]- bearing an iron-stabilized azo-anion radical ligand catalyzes these reactions. Both iron and the redox-active arylazo ligand participate synergistically during the different steps of these catalytic reactions.

Tetrahedron published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Quality Control of 350-03-8.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Nicholson, William I.; Barreteau, Fabien; Leitch, Jamie A.; Payne, Riley; Priestley, Ian; Godineau, Edouard; Battilocchio, Claudio; Browne, Duncan L. published the artcile< Direct Amidation of Esters by Ball Milling>, Quality Control of 93-60-7, the main research area is amide preparation ball milling; amine ester mechanochem amidation; ester amine hydrochloride mechanochem amidation; amidation; amides; ball milling; esters; sustainable chemistry.

The direct mechanochem. amidation of esters RC(O)OR1 (R = Cy, Ph, pyridin-2-yl, etc.; R1 = Me, Et) by ball milling is described. The operationally simple procedure requires an ester, amines R2NHR3 (R2 = H, Me, Et; R3 = i-Pr, Ph, 2,4,6-trimethylphenyl, etc.; R2R3 = -(CH2)2O(CH2)2-, -(CH2)5-, -(CH2)6-, etc.) and 1,2,3,4-tetrahydroquinoline, and substoichiometric KOtBu, and was used to prepare a large and diverse library of 78 amide structures RC(O)N(R2)R3 and (3,4-dihydroquinolin-1(2H)-yl)(phenyl)methanone with modest to excellent efficiency. Heteroaromatic and heterocyclic components are specifically shown to be amenable to this mechanochem. protocol. This direct synthesis platform has been applied to the synthesis of active pharmaceutical ingredients (APIs) and agrochems. as well as the gram-scale synthesis of an active pharmaceutical, all in the absence of a reaction solvent.

Angewandte Chemie, International Edition published new progress about Amidation. 93-60-7 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO2, Quality Control of 93-60-7.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Li, Bin; Yan, Qing-Qing; Yong, Guo-Ping published the artcile< Crystal structures and properties of four coordination polymers based on a new asymmetric ligand: Tuning structure/dimensionality by various organic solvents>, COA of Formula: C7H7NO, the main research area is cobalt nickel zinc cadmium bipyridinediyldibenzoato complex preparation crystal structure; photoluminescence magnesium cobalt nickel zinc cadmium bipyridinediyldibenzoato complex.

An asym. ligand, 4,4′-([2,3′-bipyridine]-4,6-diyl)dibenzoic acid (H2L) was successfully used to construct four new coordination polymers, [M(HL)2]n (M = Cd (1), Co (2), Zn (3)) and [Ni(L)(H2O)2]n·H2O (4), which were solvothermally synthesized and structurally characterized. In coordination polymers 1-4, two ligands bridge two metal centers through carboxylate oxygen atoms and pyridyl nitrogen atoms to form a rhombic grid motif. Amongst, each rhombic grid connects to adjacent ones through the metal nodes to construct spirolike 1-dimensional chain of 1-3 with the partially deprotonated 2-connected HL- ligands, whereas, the completely deprotonated 3- connected L2- ligands make rhombic grids construct 2-dimensional network of 4. The various structure/dimensionality of 1-4 essentially originates from the types of organic solvents, because dipolar DMF solvent results in complete deprotonated L2- in 4, conversely, polar NMP and MeCN only cause partial deprotonation of ligand in 1-3. An enhanced luminescence appears in 1 and 3, compared to H2L ligand, while 2 and 4 reveal antiferromagnetic behaviors. Also, the sensing experiments indicate that 1 and 3 possess luminescent quenching effects on sensing nitrobenzene. This work provides a promising approach to design and construct new coordination polymers with tunable structure/dimensionality by using different organic solvents.

Inorganica Chimica Acta published new progress about Antiferromagnetic exchange. 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, COA of Formula: C7H7NO.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem

Ding, Weijie; Sheng, Jie; Li, Jin; Cheng, Xu published the artcile< Electroreductive 4-pyridylation of unsaturated compounds using gaseous ammonia as a hydrogen source>, Safety of 1-(Pyridin-3-yl)ethanone, the main research area is unsaturated compound cyanopyridine electrochem reductive pyridinylation; alkylpyridine preparation.

Electrochem. radical-cross-coupling with ammonia as a terminal reductant was reported in the reactions of α-Keto esters, β-keto esters, α,β-unsaturated esters, and α,β-unsaturated ketones with 4-CN pyridine. More than 50 corresponding pyridylation products were synthesized under constant current conditions using thiourea as an essential promoter to activate the intermediate derived from 4-CN pyridine.

Organic Chemistry Frontiers published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 350-03-8 belongs to class pyridine-derivatives, and the molecular formula is C7H7NO, Safety of 1-(Pyridin-3-yl)ethanone.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem